Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50000489
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004413(CHEMBL433291 | tert-butyl 3-[1-(1-cyclohexylmethyl...)
Affinity DataIC50:  31nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006421(CHEMBL67542 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  32nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006418(CHEMBL67431 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  33nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006440(CHEMBL67500 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  37nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006438(CHEMBL305761 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  39nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006431(CHEMBL304121 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  39nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006429(CHEMBL302984 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  41nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006436(CHEMBL66684 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  81nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006433(CHEMBL406475 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  124nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006430(CHEMBL65206 | {1-[1-{1-Cyclohexylmethyl-3-[1-(2-di...)
Affinity DataIC50:  145nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006425(CHEMBL303322 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  198nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006437(CHEMBL63965 | {1-[1-[3-(4-Allyl-5-trifluoromethyl-...)
Affinity DataIC50:  206nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006419((5-{3-[2-(2-tert-Butoxycarbonylamino-3-phenyl-prop...)
Affinity DataIC50:  207nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006427(CHEMBL68229 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  240nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006422(CHEMBL309127 | {1-[1-(1-Cyclohexylmethyl-3-cyclohe...)
Affinity DataIC50:  289nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006428(CHEMBL68464 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  314nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006439(CHEMBL309128 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  359nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006424(CHEMBL63434 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  392nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006435((5-{3-[2-(2-tert-Butoxycarbonylamino-3-phenyl-prop...)
Affinity DataIC50:  396nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006432(CHEMBL308658 | {1-[1-[3-(1-Carbamoylmethyl-1H-tetr...)
Affinity DataIC50:  448nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006434(4-[2-(5-{3-[2-(2-tert-Butoxycarbonylamino-3-phenyl...)
Affinity DataIC50:  678nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006420(CHEMBL63826 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  708nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006423(CHEMBL303699 | {1-[1-(1-Cyclohexylmethyl-3-{1-[(2-...)
Affinity DataIC50:  1.29E+3nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006426(CHEMBL302255 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  3.31E+3nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed