Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50002406
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022041(CHEMBL56608 | {1-[1-{1-Cyclohexylmethyl-3-[1-(3-gu...)
Affinity DataIC50:  0.590nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022036(CHEMBL298615 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  0.990nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022033(CHEMBL418305 | {1-[1-{3-[1-(3-Aminomethyl-benzylca...)
Affinity DataIC50:  1nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022036(CHEMBL298615 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022042(CHEMBL299892 | {3-[(2-{4-[2-(2-tert-Butoxycarbonyl...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022042(CHEMBL299892 | {3-[(2-{4-[2-(2-tert-Butoxycarbonyl...)
Affinity DataIC50:  1.40nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022041(CHEMBL56608 | {1-[1-{1-Cyclohexylmethyl-3-[1-(3-gu...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022033(CHEMBL418305 | {1-[1-{3-[1-(3-Aminomethyl-benzylca...)
Affinity DataIC50:  3.30nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022036(CHEMBL298615 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022034(CHEMBL293094 | {3-[(2-{4-[2-(2-tert-Butoxycarbonyl...)
Affinity DataIC50:  6.80nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022033(CHEMBL418305 | {1-[1-{3-[1-(3-Aminomethyl-benzylca...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022041(CHEMBL56608 | {1-[1-{1-Cyclohexylmethyl-3-[1-(3-gu...)
Affinity DataIC50:  9nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022044(CHEMBL294160 | {1-[1-(1-{2-[1-(3-Aminomethyl-benzy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022030(CHEMBL291900 | {1-[1-(1-{2-[1-(3-Guanidinomethyl-b...)
Affinity DataIC50:  9nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022034(CHEMBL293094 | {3-[(2-{4-[2-(2-tert-Butoxycarbonyl...)
Affinity DataIC50:  14nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)
Affinity DataIC50:  16nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022030(CHEMBL291900 | {1-[1-(1-{2-[1-(3-Guanidinomethyl-b...)
Affinity DataIC50:  20nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022039(CHEMBL293351 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[...)
Affinity DataIC50:  20nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)
Affinity DataIC50:  25nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)
Affinity DataIC50:  26nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022034(CHEMBL293094 | {3-[(2-{4-[2-(2-tert-Butoxycarbonyl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022030(CHEMBL291900 | {1-[1-(1-{2-[1-(3-Guanidinomethyl-b...)
Affinity DataIC50:  44nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022032(CHEMBL57352 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[(...)
Affinity DataIC50:  50nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022039(CHEMBL293351 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[...)
Affinity DataIC50:  51nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022044(CHEMBL294160 | {1-[1-(1-{2-[1-(3-Aminomethyl-benzy...)
Affinity DataIC50:  54nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022040(CHEMBL3085571 | {1-[1-(1-{2-[1-(1-Carbamoyl-2-phen...)
Affinity DataIC50:  63nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022040(CHEMBL3085571 | {1-[1-(1-{2-[1-(1-Carbamoyl-2-phen...)
Affinity DataIC50:  63nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022047(CHEMBL293093 | {1-[1-(1-{2-[1-(2-Guanidino-ethylca...)
Affinity DataIC50:  64nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022032(CHEMBL57352 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[(...)
Affinity DataIC50:  92nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022031(2-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-phenyl-pr...)
Affinity DataIC50:  92nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022038(CHEMBL57268 | {1-[1-(1-{2-[1-(2-Amino-2-pyridin-2-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022044(CHEMBL294160 | {1-[1-(1-{2-[1-(3-Aminomethyl-benzy...)
Affinity DataIC50:  110nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022045(CHEMBL56703 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[(...)
Affinity DataIC50:  120nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022045(CHEMBL56703 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[(...)
Affinity DataIC50:  120nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022037(CHEMBL57627 | {1-[1-(1-{2-[1-(4-Benzyl-piperazine-...)
Affinity DataIC50:  127nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022035(CHEMBL58270 | {1-[1-(1-{2-[1-(2-Amino-ethylcarbamo...)
Affinity DataIC50:  140nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022046(CHEMBL57455 | {1-[1-{1-[2-(1-{3-[Bis-(2-hydroxy-et...)
Affinity DataIC50:  170nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022039(CHEMBL293351 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[...)
Affinity DataIC50:  210nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022032(CHEMBL57352 | {1-[1-[1-(1-Hydroxy-2-{3-methyl-1-[(...)
Affinity DataIC50:  240nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022037(CHEMBL57627 | {1-[1-(1-{2-[1-(4-Benzyl-piperazine-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022040(CHEMBL3085571 | {1-[1-(1-{2-[1-(1-Carbamoyl-2-phen...)
Affinity DataIC50:  290nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022037(CHEMBL57627 | {1-[1-(1-{2-[1-(4-Benzyl-piperazine-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022031(2-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-phenyl-pr...)
Affinity DataIC50:  350nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022047(CHEMBL293093 | {1-[1-(1-{2-[1-(2-Guanidino-ethylca...)
Affinity DataIC50:  710nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022048(3-(3-Aminomethyl-phenyl)-2-(2-{4-[2-(2-tert-butoxy...)
Affinity DataIC50:  880nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022038(CHEMBL57268 | {1-[1-(1-{2-[1-(2-Amino-2-pyridin-2-...)
Affinity DataIC50:  940nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022038(CHEMBL57268 | {1-[1-(1-{2-[1-(2-Amino-2-pyridin-2-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed