Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50006443
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049168((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity of the compound against L1210 Thymidylate synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049159((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity of the compound against L1210 Thymidylate synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049159((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049168((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049170((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049172((R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[(2-methyl-4-ox...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049175((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049176((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049164((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049165((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049167((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049158((R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[methyl-(2-meth...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049162((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049162((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049161((S)-4-((R)-1-Carboxy-ethylcarbamoyl)-2-{4-[(2-meth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049160((S)-4-((S)-1-Carboxy-ethylcarbamoyl)-2-{4-[(2-meth...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049166((R)-2-((S)-4-Carboxy-4-{4-[ethyl-(2-methyl-4-oxo-3...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049173((S)-4-((S)-1-Carboxy-2-phenyl-ethylcarbamoyl)-2-{4...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037303((R)-2-((R)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049171(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049169((R)-2-((S)-4-Carboxy-4-{4-[methyl-(2-methyl-4-oxo-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049164((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  37nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed