Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50009632
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085853(CHEMBL173251 | Sodium; [2-cyano-5-(pyridin-4-ylmet...)
Affinity DataIC50:  5nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085859((2-Chloro-phenyl)-[2-cyano-5-(pyridin-4-ylmethoxy)...)
Affinity DataIC50:  6nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085845(CHEMBL174235 | [5-(Benzooxazol-6-ylmethoxy)-2-cyan...)
Affinity DataIC50:  6nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085833(CHEMBL172144 | Sodium; [5-(benzo[1,3]dioxol-5-ylme...)
Affinity DataIC50:  7nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085831(CHEMBL174092 | [2-Cyano-5-(pyridin-4-ylmethoxy)-ph...)
Affinity DataIC50:  9nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085861(CHEMBL170681 | [5-(Benzooxazol-6-ylmethoxy)-2-cyan...)
Affinity DataIC50:  9nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085830(CHEMBL173792 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)
Affinity DataIC50:  12nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085838(CHEMBL352536 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)
Affinity DataIC50:  14nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085855(CHEMBL170202 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)
Affinity DataIC50:  16nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085840((2-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy...)
Affinity DataIC50:  17nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085835(CHEMBL427294 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  20nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085854(CHEMBL171638 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  22nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085832(CHEMBL171513 | [2-Cyano-5-(2-fluoro-pyridin-4-ylme...)
Affinity DataIC50:  23nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085839(CHEMBL170348 | [2-Cyano-5-(pyridin-3-ylmethoxy)-ph...)
Affinity DataIC50:  30nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085864(CHEMBL354740 | [2-Cyano-5-(thiazol-5-ylmethoxy)-ph...)
Affinity DataIC50:  30nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085856(CHEMBL355413 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)
Affinity DataIC50:  41nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085858((2-Chloro-phenyl)-[2-cyano-5-(pyridazin-4-ylmethox...)
Affinity DataIC50:  44nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085860((5-Benzyloxy-2-cyano-phenoxy)-o-tolyl-acetic acid ...)
Affinity DataIC50:  49nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085844((2-Bromo-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy)...)
Affinity DataIC50:  51nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085837(CHEMBL170715 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  53nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085836(CHEMBL172412 | [2-Cyano-5-(furan-3-ylmethoxy)-phen...)
Affinity DataIC50:  68nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085852(CHEMBL174229 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  70nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085843(CHEMBL173444 | [5-(Benzooxazol-5-ylmethoxy)-2-cyan...)
Affinity DataIC50:  75nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085863((3-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy...)
Affinity DataIC50:  98nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085862(CHEMBL366788 | [2-Cyano-5-(isothiazol-3-ylmethoxy)...)
Affinity DataIC50:  220nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085841((4-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy...)
Affinity DataIC50:  504nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085848(CHEMBL172164 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  529nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085850(CHEMBL172879 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  630nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085846(CHEMBL173054 | [2-Cyano-5-(2,6-dimethyl-benzyloxy)...)
Affinity DataIC50:  857nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085847(CHEMBL171702 | [2-Cyano-5-(2,3-dihydro-benzo[1,4]d...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085849(CHEMBL172880 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085842(CHEMBL173565 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)
Affinity DataIC50:  2.85E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085834(CHEMBL172691 | [5-(Benzo[1,3]dioxol-4-ylmethoxy)-2...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085851(CHEMBL171760 | [2-Cyano-5-(3,4,5-trimethoxy-benzyl...)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085857(CHEMBL173431 | [2-Cyano-5-(pyridin-2-ylmethoxy)-ph...)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed