Compile Data Set for Download or QSAR
maximum 50k data
Found 77 Enz. Inhib. hit(s) with all data for entry = 50014038
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137488(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137475(1-Cyclohexyl-2-(1-methyl-1H-pyrrol-2-yl)-1H-benzoi...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137467(1-Cyclohexyl-2-thiophen-2-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137504(1-Cyclohexyl-2-furan-2-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137480(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137462(1-Cyclohexyl-2-thiazol-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137458(1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137490(1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50:  6.33E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137468(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137479(1-Cyclohexyl-2-phenyl-1H-benzoimidazole-5-carboxyl...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137481(1-Cyclohexyl-2-(1H-imidazol-2-yl)-1H-benzoimidazol...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137464(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137487(1-Cyclopentyl-2-pyridin-2-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137493(1-Cyclohexyl-2-{4-[(3-dimethylamino-propylcarbamoy...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137499(1-(2-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimi...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137476(1-Cyclohexyl-2-{4-[(3-dimethylamino-propylcarbamoy...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137473(1-Cyclohexyl-2-pyridin-4-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137484(1-Cyclohexyl-2-(2-methyl-propenyl)-1H-benzoimidazo...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137460(1,2-Dicyclohexyl-1H-benzoimidazole-5-carboxylic ac...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137492(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137503(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137472(1-Cyclohexyl-2-pyridin-3-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137463(2-(5-Carboxy-furan-2-yl)-1-cyclohexyl-1H-benzoimid...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137459(2-(5-Bromo-furan-2-yl)-1-cyclohexyl-1H-benzoimidaz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137483(1-Cyclohexyl-2-(3-phenyl-1H-pyrazol-4-yl)-1H-benzo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137470(1-Cyclohexyl-2-(5-ethyl-furan-2-yl)-1H-benzoimidaz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137465(1-Cyclohexyl-2-(5-ethyl-thiophen-2-yl)-1H-benzoimi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137477(1-Cyclohexyl-2-(5-methyl-3H-imidazol-4-yl)-1H-benz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137482(1-Cyclohexyl-2-(4,5-dimethyl-furan-2-yl)-1H-benzoi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137498(1-Cyclohexyl-2-(5-hydroxymethyl-furan-2-yl)-1H-ben...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137471(2-(5-Carboxy-thiophen-2-yl)-1-cyclohexyl-1H-benzoi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137495(1-Cyclohexyl-2-(6-methyl-pyridin-2-yl)-1H-benzoimi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137496(1-Cyclohexyl-2-quinolin-2-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137501(1-Cyclohexyl-2-(5-methyl-thiophen-2-yl)-1H-benzoim...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137500(1-Cyclohexyl-2-(3-methyl-1H-indol-2-yl)-1H-benzoim...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137485(2-[5-(4-Chloro-phenyl)-furan-2-yl]-1-cyclohexyl-1H...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137469(2-Benzoyl-1-cyclohexyl-1H-benzoimidazole-5-carboxy...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137502(1-Cycloheptyl-2-pyridin-2-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137491(1-(4-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimi...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137486(2-Benzofuran-2-yl-1-cyclohexyl-1H-benzoimidazole-5...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137478(1-Cyclohexyl-1H-benzoimidazole-2,5-dicarboxylic ac...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137461(1-Cyclobutyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137494(1-Cyclohexyl-2-(2,4,6-trimethyl-phenyl)-1H-benzoim...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137505(1-(1-Ethyl-propyl)-2-pyridin-2-yl-1H-benzoimidazol...)
Affinity DataIC50:  1.39E+5nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137497(1-Cyclohexyl-1H-benzoimidazole-5-carboxylic acid |...)
Affinity DataIC50:  1.86E+5nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137488(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137472(1-Cyclohexyl-2-pyridin-3-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137467(1-Cyclohexyl-2-thiophen-2-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137481(1-Cyclohexyl-2-(1H-imidazol-2-yl)-1H-benzoimidazol...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137490(1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-c...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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