Compile Data Set for Download or QSAR
maximum 50k data
Found 57 Enz. Inhib. hit(s) with all data for entry = 50014159
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138858(CHEMBL154579 | [(S)-1-(4-Phenyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  0.210nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138853(CHEMBL157072 | [(S)-1-(4-Bromo-1H-pyrazol-3-ylamin...)
Affinity DataIC50:  0.240nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138876(CHEMBL345569 | [(S)-1-(4-Fluoro-1H-indazol-3-ylami...)
Affinity DataIC50:  0.260nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138866(CHEMBL156764 | [(S)-1-(1-Methyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  0.410nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138869(CHEMBL154959 | [(S)-1-(4-Methyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  0.470nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138879(CHEMBL345982 | [(S)-1-(5-Phenyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  0.650nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138871(CHEMBL154818 | [(S)-1-(5-Methyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  0.710nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138868(CHEMBL154862 | [(S)-1-(1H-Pyrazol-3-ylaminooxalyl)...)
Affinity DataIC50:  0.770nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138870(CHEMBL347004 | [(S)-1-(4-Cyano-1H-pyrazol-3-ylamin...)
Affinity DataIC50:  0.910nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138846(3-[(S)-3-(1-Isopropyl-2-methyl-propoxycarbonylamin...)
Affinity DataIC50:  1.70nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138858(CHEMBL154579 | [(S)-1-(4-Phenyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842(2,4-dimethylpentan-3-yl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  2.54nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138864(CHEMBL351111 | [(S)-1-(Isoquinolin-3-ylaminooxalyl...)
Affinity DataIC50:  4.80nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138852(CHEMBL356378 | [(S)-1-(Isoxazol-3-ylaminooxalyl)-p...)
Affinity DataIC50:  5.10nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138869(CHEMBL154959 | [(S)-1-(4-Methyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138878(CHEMBL422686 | [(S)-1-(Thiophen-2-ylmethyl)-aminoo...)
Affinity DataIC50:  9.20nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138866(CHEMBL156764 | [(S)-1-(1-Methyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  11nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138879(CHEMBL345982 | [(S)-1-(5-Phenyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  12nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138868(CHEMBL154862 | [(S)-1-(1H-Pyrazol-3-ylaminooxalyl)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138843(CHEMBL351552 | {(S)-1-Cyclohexylmethyl-2-oxo-2-[(t...)
Affinity DataIC50:  14nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138865(CHEMBL155148 | [(S)-1-(2-Cyclobutyl-2H-pyrazol-3-y...)
Affinity DataIC50:  15nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138854(CHEMBL345356 | [(S)-1-(2-Phenyl-2H-pyrazol-3-ylami...)
Affinity DataIC50:  15nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138849(CHEMBL157224 | [(S)-1-(2-Isopropyl-2H-pyrazol-3-yl...)
Affinity DataIC50:  17nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138847(CHEMBL155123 | [(S)-1-(2-Cyclopentyl-2H-pyrazol-3-...)
Affinity DataIC50:  20nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138877(CHEMBL346102 | [(S)-1-(2-Cyclohexyl-2H-pyrazol-3-y...)
Affinity DataIC50:  22nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138859(CHEMBL157430 | [(S)-3-Methyl-1-(thiophen-2-ylmethy...)
Affinity DataIC50:  24nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138867(CHEMBL157911 | [(S)-1-(2-Pyridin-4-yl-2H-pyrazol-3...)
Affinity DataIC50:  25nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138855(CHEMBL345136 | [(S)-1-(2-Ethyl-2H-pyrazol-3-ylamin...)
Affinity DataIC50:  26nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138848(CHEMBL155592 | [(S)-1-(2-Cyclopropylmethyl-2H-pyra...)
Affinity DataIC50:  27nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138875(CHEMBL152634 | {(S)-1-Benzyl-2-oxo-2-[(thiophen-2-...)
Affinity DataIC50:  27nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138851(CHEMBL152633 | [(S)-1-(2-Methyl-2H-pyrazol-3-ylami...)
Affinity DataIC50:  32nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138841(CHEMBL154584 | [(S)-1-(Pyridin-2-ylaminooxalyl)-pe...)
Affinity DataIC50:  32nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138872(CHEMBL346739 | [(S)-1-(2-Isobutyl-2H-pyrazol-3-yla...)
Affinity DataIC50:  39nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138874(CHEMBL156497 | [(S)-1-(Thiazol-2-ylaminooxalyl)-pe...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138860(CHEMBL156832 | [(S)-2-Methyl-1-(thiophen-2-ylmethy...)
Affinity DataIC50:  47nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50137790(((S)-1-Formyl-pentyl)-carbamic acid tert-butyl est...)
Affinity DataIC50:  51nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138845(CHEMBL154173 | [(S)-1-(Pyrazin-2-ylaminooxalyl)-pe...)
Affinity DataIC50:  52nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138844(CHEMBL155183 | {(S)-1-[2-(3,3-Dimethyl-butyl)-2H-p...)
Affinity DataIC50:  62nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138850(CHEMBL155297 | [(S)-1-(2-Pyridin-2-yl-2H-pyrazol-3...)
Affinity DataIC50:  62nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138861(CHEMBL156496 | [(S)-1-([1,3,4]Thiadiazol-2-ylamino...)
Affinity DataIC50:  83nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138857(CHEMBL347137 | [(S)-2-Methyl-1-(thiophen-2-ylmethy...)
Affinity DataIC50:  87nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138863(CHEMBL156677 | [(S)-1-(Pyridin-3-ylaminooxalyl)-pe...)
Affinity DataIC50:  95nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138862(CHEMBL153943 | [(S)-1-(Quinolin-2-ylaminooxalyl)-p...)
Affinity DataIC50:  250nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138873(CHEMBL433890 | {(S)-1-Methyl-2-oxo-2-[(thiophen-2-...)
Affinity DataIC50:  360nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138867(CHEMBL157911 | [(S)-1-(2-Pyridin-4-yl-2H-pyrazol-3...)
Affinity DataIC50:  470nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138854(CHEMBL345356 | [(S)-1-(2-Phenyl-2H-pyrazol-3-ylami...)
Affinity DataIC50:  790nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138849(CHEMBL157224 | [(S)-1-(2-Isopropyl-2H-pyrazol-3-yl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138847(CHEMBL155123 | [(S)-1-(2-Cyclopentyl-2H-pyrazol-3-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138865(CHEMBL155148 | [(S)-1-(2-Cyclobutyl-2H-pyrazol-3-y...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138877(CHEMBL346102 | [(S)-1-(2-Cyclohexyl-2H-pyrazol-3-y...)
Affinity DataIC50: >1.20E+3nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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