Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50017714
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185601(CHEMBL380059)
Affinity DataIC50:  24nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185595((E)-2-(N-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185585((E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185590((2-{[(2E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185596((E)-5-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185604((E)-2-((4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-di...)
Affinity DataIC50:  132nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185603((E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)
Affinity DataIC50:  168nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185599((E)-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  246nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185587(7-hydroxy-5-methoxy-4-methyl-6-(3-methylbut-2-enyl...)
Affinity DataIC50:  254nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185594((E)-7-hydroxy-5-methoxy-6-(4-methoxy-3-methylbut-2...)
Affinity DataIC50:  273nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185588((E)-dimethyl 4-(4-hydroxy-6-methoxy-7-methyl-3-oxo...)
Affinity DataIC50:  289nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185598((2-{[(E)-4-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3...)
Affinity DataIC50:  498nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185602((E)-2-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-d...)
Affinity DataIC50:  499nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185600((1E,3E)-5-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-...)
Affinity DataIC50:  506nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185597((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50:  749nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185583((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50:  785nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185593((E)-diethyl 2-(4-(4-hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185591((E)-2-((4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50185584((E)-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed