Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50018335
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194539(4-(3-(2-fluorophenyl)propanamido)-N,N-diisopropyl-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194512(CHEMBL216955 | N,N-diisopropyl-3-phenyl-4-(3-pheny...)
Affinity DataIC50:  94nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194549(CHEMBL217222 | N,N-diisopropyl-3-phenyl-4-(3-pheny...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194510(CHEMBL386441 | methyl 5-(diisopropylamino)-3-(3-(3...)
Affinity DataIC50:  113nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194540(CHEMBL217011 | methyl 3-(3-bromophenyl)-5-(diisopr...)
Affinity DataIC50:  137nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194514(CHEMBL217921 | methyl 4-(3-bromophenyl)-5-(diisopr...)
Affinity DataIC50:  147nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194527(4-(3-(2-fluorobenzyl)ureido)-N,N-diisopropyl-3-phe...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194517(CHEMBL385737 | methyl 3-(3-cyanophenyl)-5-(diisopr...)
Affinity DataIC50:  184nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194528(CHEMBL411970 | methyl 3-(4-cyanophenyl)-5-(diisopr...)
Affinity DataIC50:  215nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194524(CHEMBL217291 | N,N-diisopropyl-4-(3-(4-methylbenzy...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194544(CHEMBL218128 | N1,N1-diisopropyl-3-phenyl-N5-(1-ph...)
Affinity DataIC50:  249nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194516(CHEMBL217684 | N,N-diisopropyl-3-phenyl-4-(4-pheny...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194547(CHEMBL384780 | N,N-diisopropyl-4-(3-(3-methylbenzy...)
Affinity DataIC50:  252nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194531(CHEMBL216086 | methyl 5-(diisopropylamino)-5-oxo-3...)
Affinity DataIC50:  252nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194513(CHEMBL384095 | N,N-diisopropyl-4-(3-(4-methoxybenz...)
Affinity DataIC50:  256nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194530((3R,4S)-methyl 5-(diisopropylamino)-5-oxo-3-phenyl...)
Affinity DataIC50:  265nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194546(CHEMBL384974 | methyl 5-(diisopropylamino)-5-oxo-4...)
Affinity DataIC50:  266nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194535(CHEMBL216436 | N,N-diisopropyl-3-phenyl-4-(3-((R)-...)
Affinity DataIC50:  283nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194541(CHEMBL385960 | N,N-diisopropyl-4-(3-phenethylureid...)
Affinity DataIC50:  298nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194521(CHEMBL386226 | methyl 4-(3-cyanophenyl)-5-(diisopr...)
Affinity DataIC50:  326nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194526(4-(3-(3-fluorobenzyl)ureido)-N,N-diisopropyl-3-phe...)
Affinity DataIC50:  341nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194523(4-(3-(4-fluorobenzyl)ureido)-N,N-diisopropyl-3-phe...)
Affinity DataIC50:  353nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194536(4-(3-(4-bromobenzyl)ureido)-N,N-diisopropyl-3-phen...)
Affinity DataIC50:  362nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194543(CHEMBL384706 | N1,N1-diisopropyl-N5-phenethyl-3-ph...)
Affinity DataIC50:  410nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194548(CHEMBL217251 | N5-(2-fluorobenzyl)-N1,N1-diisoprop...)
Affinity DataIC50:  432nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194529(CHEMBL216254 | N,N-diisopropyl-3-phenyl-4-(3-((S)-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194533(4-(3-(2-chlorophenyl)propanamido)-N,N-diisopropyl-...)
Affinity DataIC50:  498nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194545(CHEMBL439539 | N1,N1-diisopropyl-3-phenyl-N5-(3-ph...)
Affinity DataIC50:  589nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194538(CHEMBL216310 | methyl 5-(diisopropylamino)-5-oxo-3...)
Affinity DataIC50:  708nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194515(4-(3-(2-chlorobenzyl)ureido)-N,N-diisopropyl-3-phe...)
Affinity DataIC50:  757nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194509(4-(2-amino-3-(2-fluorophenyl)propanamido)-N,N-diis...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194534(CHEMBL216338 | N5-(2-(tert-butylthio)ethyl)-N1,N1-...)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194519(CHEMBL436956 | methyl 3-(2-cyanophenyl)-5-(diisopr...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194537(CHEMBL217473 | N1,N1-diisopropyl-N5-methyl-3-pheny...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194520(CHEMBL385920 | N1,N1-diisopropyl-3-phenyl-N5-((4-p...)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194511((3S,4S)-methyl 5-(diisopropylamino)-5-oxo-3-phenyl...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194532(CHEMBL386899 | methyl 5-(diisopropylamino)-5-oxo-4...)
Affinity DataIC50:  3.84E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194542(CHEMBL216255 | methyl 5-(diisopropylamino)-5-oxo-4...)
Affinity DataIC50:  5.32E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194522(CHEMBL385460 | methyl 5-(diisopropylamino)-5-oxo-4...)
Affinity DataIC50:  6.35E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194518(CHEMBL216309 | methyl 5-(diisopropylamino)-5-oxo-3...)
Affinity DataIC50:  6.87E+3nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194525(CHEMBL384309 | methyl 5-(diisopropylamino)-5-oxo-3...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of Kv1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed