Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50028313
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50128164(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particles in presence of buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50128164(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276348((2R, aS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroetho...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human plasma-derived CETP activity by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276347((+/-)-1,1,1-trifluoro-3-(2-(3-(1,1,2,2-tetrafluoro...)
Affinity DataIC50:  45nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50128164(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...)
Affinity DataIC50:  59nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particles in presence of huma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276348((2R, aS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroetho...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CETP-mediated transfer of [3H]cholesteryl ester from HDL in human plasma after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276280(3-(5-(4-chloro-3-ethylphenoxy)-2 -(3-(1,1,2,2-tetr...)
Affinity DataIC50:  400nMAssay Description:Inhibition of CETP (unknown origin)-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276348((2R, aS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroetho...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CETP-mediated transfer of cholesteryl ester to LDL/VLDL in human plasma by Roar assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed