Compile Data Set for Download or QSAR
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Found 19 Enz. Inhib. hit(s) with all data for entry = 50033581
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347610(CHEMBL1802990)
Affinity DataIC50:  31nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347615(CHEMBL1803019)
Affinity DataIC50:  37nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347609(CHEMBL1802989)
Affinity DataIC50:  40nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347616(CHEMBL1803020)
Affinity DataIC50:  45nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM36350(6-[4-(Trifluoromethyl)phenyl]-3,4-dihydro-2(1H)-qu...)
Affinity DataIC50:  46nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347606(CHEMBL1802986)
Affinity DataIC50:  52nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347617(CHEMBL1803021)
Affinity DataIC50:  58nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347612(CHEMBL1803016)
Affinity DataIC50:  84nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347613(CHEMBL1803017)
Affinity DataIC50:  85nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347607(CHEMBL1802987)
Affinity DataIC50:  95nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50220185(1-(3-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)urea...)
Affinity DataIC50:  100nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347614(CHEMBL1803018)
Affinity DataIC50:  120nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50220162(CHEMBL243883 | N-[4'-(trifluoromethyl)-4-biphenyly...)
Affinity DataIC50:  140nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347618(CHEMBL1803022)
Affinity DataIC50:  170nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347611(CHEMBL1802991)
Affinity DataIC50:  180nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50322579(2-(trifluoromethyl)-9H-carbazole | CHEMBL1173704)
Affinity DataIC50:  210nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347608(CHEMBL1802988)
Affinity DataIC50:  330nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347605(CHEMBL1802985)
Affinity DataIC50: >6.30E+3nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347604(CHEMBL1802984)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed