Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50035904
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  24nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | AMINOPTE...)
Affinity DataIC50:  25nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50010933(2-{4-[(4-Amino-pteridin-6-ylmethyl)-methyl-amino]-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50010935(2-{4-[(4-Amino-pteridin-6-ylmethyl)-amino]-benzoyl...)
Affinity DataIC50:  1.90E+4nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50010934(2-{4-[(4-Amino-2-methyl-pteridin-6-ylmethyl)-methy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50010936(2-{4-[(4-Amino-2-methyl-pteridin-6-ylmethyl)-amino...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed