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Found 34 Enz. Inhib. hit(s) with all data for entry = 50036183
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50368742(CHEMBL1169525)
Affinity DataKi:  0.0170nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042730(4-Amino-5-chloro-N-[5-(4-fluoro-benzyl)-octahydro-...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50456207(CHEMBL2112607)
Affinity DataKi:  0.0280nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042733((9-Benzyl-3,9-diaza-bicyclo[3.3.1]non-3-yl)-(5-bro...)
Affinity DataKi:  0.0330nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042732(4-Amino-N-(9-benzyl-9-aza-bicyclo[3.3.1]non-3-yl)-...)
Affinity DataKi:  0.0360nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50456208(CHEMBL2112605)
Affinity DataKi:  0.0380nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042731(5-Bromo-N-[1-(4-fluoro-benzyl)-piperidin-4-yl]-2,3...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50040079(CHEMBL308524 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...)
Affinity DataKi:  0.160nMAssay Description:In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50456207(CHEMBL2112607)
Affinity DataKi:  0.210nMAssay Description:In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50007514(CHEMBL75842 | N-(1-Benzyl-piperidin-4-yl)-5-bromo-...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042725(CHEMBL340471 | N-[1-(4-Fluoro-benzyl)-piperidin-4-...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042731(5-Bromo-N-[1-(4-fluoro-benzyl)-piperidin-4-yl]-2,3...)
Affinity DataKi:  0.450nMAssay Description:In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50007525(CHEMBL123282 | N-(1-Benzyl-piperidin-4-yl)-2,3-dim...)
Affinity DataKi:  0.630nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042726(4-Amino-5-chloro-N-[1-(4-fluoro-benzyl)-piperidin-...)
Affinity DataKi:  0.950nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50132693(4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042730(4-Amino-5-chloro-N-[5-(4-fluoro-benzyl)-octahydro-...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50368742(CHEMBL1169525)
Affinity DataKi:  3.70nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042725(CHEMBL340471 | N-[1-(4-Fluoro-benzyl)-piperidin-4-...)
Affinity DataKi:  5.90nMAssay Description:In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50132693(4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM84746(BRL 34778 | BRL-34778)
Affinity DataKi: >10nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50456207(CHEMBL2112607)
Affinity DataKi:  84nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50132693(4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...)
Affinity DataKi:  89nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042731(5-Bromo-N-[1-(4-fluoro-benzyl)-piperidin-4-yl]-2,3...)
Affinity DataKi:  94nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042726(4-Amino-5-chloro-N-[1-(4-fluoro-benzyl)-piperidin-...)
Affinity DataKi:  283nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132693(4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...)
Affinity DataKi:  600nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042726(4-Amino-5-chloro-N-[1-(4-fluoro-benzyl)-piperidin-...)
Affinity DataKi:  1.30E+3nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50456207(CHEMBL2112607)
Affinity DataKi:  1.30E+3nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042725(CHEMBL340471 | N-[1-(4-Fluoro-benzyl)-piperidin-4-...)
Affinity DataKi:  1.84E+3nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042730(4-Amino-5-chloro-N-[5-(4-fluoro-benzyl)-octahydro-...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM84746(BRL 34778 | BRL-34778)
Affinity DataKi:  2.25E+3nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042725(CHEMBL340471 | N-[1-(4-Fluoro-benzyl)-piperidin-4-...)
Affinity DataKi:  3.00E+3nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042731(5-Bromo-N-[1-(4-fluoro-benzyl)-piperidin-4-yl]-2,3...)
Affinity DataKi:  3.00E+3nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50368742(CHEMBL1169525)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed