BindingDB PrimarySearch

Found 70 Enz. Inhib. hit(s) with all data for entry = 50040240

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)

IC50: 8nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391185(CHEMBL2088663)

IC50: 91nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)

IC50: 150nMAssay Description:Inhibition of PI3K p110gamma by fluorescence based immunoassayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
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Curated by ChEMBL

BDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)

IC50: 200nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391185(CHEMBL2088663)

IC50: 295nMAssay Description:Inhibition of PI3K p110gamma by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391186(CHEMBL2088664)

IC50: 1.50E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391187(CHEMBL2088665)

IC50: 1.50E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391195(CHEMBL2088673)

IC50: 1.80E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391184(CHEMBL2088662)

IC50: 1.90E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391187(CHEMBL2088665)

IC50: 2.20E+3nMAssay Description:Inhibition of PI3K p110gamma by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
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Curated by ChEMBL

BDBM50391194(CHEMBL2088672)

IC50: 2.60E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391196(CHEMBL2088674)

IC50: 2.90E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391197(CHEMBL2088675)

IC50: 3.30E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
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Curated by ChEMBL

BDBM50391200(CHEMBL2088661)

IC50: 4.10E+3nMAssay Description:Inhibition of PI3K p110gamma by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
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Curated by ChEMBL

BDBM50391192(CHEMBL2088670)

IC50: 4.20E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391191(CHEMBL2088669)

IC50: 5.00E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
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Curated by ChEMBL

BDBM50391182(CHEMBL2088659)

IC50: 5.00E+3nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391200(CHEMBL2088661)

IC50: 5.10E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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antibodypedia antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391186(CHEMBL2088664)

IC50: 5.20E+3nMAssay Description:Inhibition of PI3K p110gamma by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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B.MOAD DrugBank antibodypedia GoogleScholar

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
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Curated by ChEMBL

BDBM50391181(CHEMBL2088658)

IC50: 5.60E+3nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391183(CHEMBL2088660)

IC50: 6.00E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391199(CHEMBL2088677)

IC50: 6.30E+3nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
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Curated by ChEMBL

BDBM50391186(CHEMBL2088664)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391187(CHEMBL2088665)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
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GoogleScholar

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391188(CHEMBL2088666)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391189(CHEMBL2088667)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391190(CHEMBL2088668)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391191(CHEMBL2088669)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391192(CHEMBL2088670)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391193(CHEMBL2088671)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391194(CHEMBL2088672)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391195(CHEMBL2088673)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391196(CHEMBL2088674)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391197(CHEMBL2088675)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391198(CHEMBL2088676)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universit£

Curated by ChEMBL

BDBM50391199(CHEMBL2088677)

IC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

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Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391181(CHEMBL2088658)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid

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Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391183(CHEMBL2088660)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391200(CHEMBL2088661)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391184(CHEMBL2088662)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391185(CHEMBL2088663)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391186(CHEMBL2088664)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391187(CHEMBL2088665)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391188(CHEMBL2088666)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391189(CHEMBL2088667)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391190(CHEMBL2088668)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391191(CHEMBL2088669)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391192(CHEMBL2088670)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391193(CHEMBL2088671)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50391194(CHEMBL2088672)

IC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

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