Compile Data Set for Download or QSAR
Found 116 Enz. Inhib. hit(s) with all data for entry = 137
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329418(2-Phenyl-5-pyridin-4-yl-1H-pyrrole-3-carboxamide |...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C16H13N3O/c17-16(20)13-10-14(11-6-8-18-9-7-11)19-15(13)12-4-2-1-3-5-12/h1-10,19H,(H2,17,20)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187800(US9670191, M4)
Show SMILES Nc1nccc(n1)-c1cc(C(=O)NCC2CCCCC2)c([nH]1)-c1ccccc1
Show InChI InChI=1S/C22H25N5O/c23-22-24-12-11-18(27-22)19-13-17(20(26-19)16-9-5-2-6-10-16)21(28)25-14-15-7-3-1-4-8-15/h2,5-6,9-13,15,26H,1,3-4,7-8,14H2,(H,25,28)(H2,23,24,27)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329425(2-(3-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(F)c1)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-2-11(8-12)15-13(16(18)21)9-14(20-15)10-4-6-19-7-5-10/h1-9,20H,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329415(2-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(F)cc1)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-11(2-4-12)15-13(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329470(2-(3-Bromo-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(Br)c1)-c1ccncc1
Show InChI InChI=1S/C16H12BrN3O/c17-12-3-1-2-11(8-12)15-13(16(18)21)9-14(20-15)10-4-6-19-7-5-10/h1-9,20H,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329467(2-(4-Bromo-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(Br)cc1)-c1ccncc1
Show InChI InChI=1S/C16H12BrN3O/c17-12-3-1-11(2-4-12)15-13(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187216(US9670191, A7)
Show SMILES Cc1ccccc1-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O/c1-11-4-2-3-5-13(11)16-14(17(18)21)10-15(20-16)12-6-8-19-9-7-12/h2-10,20H,1H3,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329449(5-Pyridin-4-yl-2-m-tolyl-1H-pyrrole-3-carboxamide ...)
Show SMILES Cc1cccc(c1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O/c1-11-3-2-4-13(9-11)16-14(17(18)21)10-15(20-16)12-5-7-19-8-6-12/h2-10,20H,1H3,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329431(5-Pyridin-4-yl-2-p-tolyl-1H-pyrrole-3-carboxamide ...)
Show SMILES Cc1ccc(cc1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O/c1-11-2-4-13(5-3-11)16-14(17(18)21)10-15(20-16)12-6-8-19-9-7-12/h2-10,20H,1H3,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329428(2-(2-Methoxy-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-c...)
Show SMILES COc1ccccc1-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O2/c1-22-15-5-3-2-4-12(15)16-13(17(18)21)10-14(20-16)11-6-8-19-9-7-11/h2-10,20H,1H3,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329465(2-(3-Methoxy-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-c...)
Show SMILES COc1cccc(c1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O2/c1-22-13-4-2-3-12(9-13)16-14(17(18)21)10-15(20-16)11-5-7-19-8-6-11/h2-10,20H,1H3,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329414(2-(4-Methoxy-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-c...)
Show SMILES COc1ccc(cc1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C17H15N3O2/c1-22-13-4-2-12(3-5-13)16-14(17(18)21)10-15(20-16)11-6-8-19-9-7-11/h2-10,20H,1H3,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187229(US9670191, A20)
Show SMILES Cc1cccc(-c2[nH]c(cc2C(N)=O)-c2ccncc2)c1C
Show InChI InChI=1S/C18H17N3O/c1-11-4-3-5-14(12(11)2)17-15(18(19)22)10-16(21-17)13-6-8-20-9-7-13/h3-10,21H,1-2H3,(H2,19,22)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187240(US9670191, C1)
Show SMILES NC(=O)c1cc([nH]c1-c1ccsc1)-c1ccncc1
Show InChI InChI=1S/C14H11N3OS/c15-14(18)11-7-12(9-1-4-16-5-2-9)17-13(11)10-3-6-19-8-10/h1-8,17H,(H2,15,18)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187241(US9670191, C2)
Show SMILES NC(=O)c1cc([nH]c1-c1ccoc1)-c1ccncc1
Show InChI InChI=1S/C14H11N3O2/c15-14(18)11-7-12(9-1-4-16-5-2-9)17-13(11)10-3-6-19-8-10/h1-8,17H,(H2,15,18)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329417(5-(3-Fluoro-pyridin-4-yl)-2-phenyl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccncc1F
Show InChI InChI=1S/C16H12FN3O/c17-13-9-19-7-6-11(13)14-8-12(16(18)21)15(20-14)10-4-2-1-3-5-10/h1-9,20H,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329427(5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccnc(N)n1
Show InChI InChI=1S/C15H13N5O/c16-14(21)10-8-12(11-6-7-18-15(17)20-11)19-13(10)9-4-2-1-3-5-9/h1-8,19H,(H2,16,21)(H2,17,18,20)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329430(5-(2-Amino-pyrimidin-4-yl)-2-thiophen-3-yl-1H-pyrr...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccsc1)-c1ccnc(N)n1
Show InChI InChI=1S/C13H11N5OS/c14-12(19)8-5-10(9-1-3-16-13(15)18-9)17-11(8)7-2-4-20-6-7/h1-6,17H,(H2,14,19)(H2,15,16,18)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329463(2-Phenyl-5-(2-phenylamino-pyrimidin-4-yl)-1H-pyrro...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccnc(Nc2ccccc2)n1
Show InChI InChI=1S/C21H17N5O/c22-20(27)16-13-18(25-19(16)14-7-3-1-4-8-14)17-11-12-23-21(26-17)24-15-9-5-2-6-10-15/h1-13,25H,(H2,22,27)(H,23,24,26)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329422(5-(2-Amino-pyrimidin-4-yl)-1-ethyl-2-phenyl-1H-pyr...)
Show SMILES CCn1c(cc(C(N)=O)c1-c1ccccc1)-c1ccnc(N)n1
Show InChI InChI=1S/C17H17N5O/c1-2-22-14(13-8-9-20-17(19)21-13)10-12(16(18)23)15(22)11-6-4-3-5-7-11/h3-10H,2H2,1H3,(H2,18,23)(H2,19,20,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329436(5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...)
Show SMILES CC(C)NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccnc(N)n1
Show InChI InChI=1S/C18H19N5O/c1-11(2)21-17(24)13-10-15(14-8-9-20-18(19)23-14)22-16(13)12-6-4-3-5-7-12/h3-11,22H,1-2H3,(H,21,24)(H2,19,20,23)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329435(5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...)
Show SMILES Nc1nccc(n1)-c1cc(C(=O)NCc2ccccc2)c([nH]1)-c1ccccc1
Show InChI InChI=1S/C22H19N5O/c23-22-24-12-11-18(27-22)19-13-17(20(26-19)16-9-5-2-6-10-16)21(28)25-14-15-7-3-1-4-8-15/h1-13,26H,14H2,(H,25,28)(H2,23,24,27)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329416(2-(2-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1F)-c1ccncc1
Show InChI InChI=1S/C16H12FN3O/c17-13-4-2-1-3-11(13)15-12(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329471(2-(2-Nitro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1[N+]([O-])=O)-c1ccncc1
Show InChI InChI=1S/C16H12N4O3/c17-16(21)12-9-13(10-5-7-18-8-6-10)19-15(12)11-3-1-2-4-14(11)20(22)23/h1-9,19H,(H2,17,21)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329423(2-(3-Nitro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(c1)[N+]([O-])=O)-c1ccncc1
Show InChI InChI=1S/C16H12N4O3/c17-16(21)13-9-14(10-4-6-18-7-5-10)19-15(13)11-2-1-3-12(8-11)20(22)23/h1-9,19H,(H2,17,21)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329460(2-(4-Nitro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(cc1)[N+]([O-])=O)-c1ccncc1
Show InChI InChI=1S/C16H12N4O3/c17-16(21)13-9-14(10-5-7-18-8-6-10)19-15(13)11-1-3-12(4-2-11)20(22)23/h1-9,19H,(H2,17,21)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187225(US9670191, A16)
Show SMILES CC(=O)c1cccc(c1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C18H15N3O2/c1-11(22)13-3-2-4-14(9-13)17-15(18(19)23)10-16(21-17)12-5-7-20-8-6-12/h2-10,21H,1H3,(H2,19,23)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187226(US9670191, A17)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(CO)c1)-c1ccncc1
Show InChI InChI=1S/C17H15N3O2/c18-17(22)14-9-15(12-4-6-19-7-5-12)20-16(14)13-3-1-2-11(8-13)10-21/h1-9,20-21H,10H2,(H2,18,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187227(US9670191, A18)
Show SMILES CC(=O)Nc1cccc(c1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C18H16N4O2/c1-11(23)21-14-4-2-3-13(9-14)17-15(18(19)24)10-16(22-17)12-5-7-20-8-6-12/h2-10,22H,1H3,(H2,19,24)(H,21,23)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187228(US9670191, A19)
Show SMILES Cc1ccc(C)c(c1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C18H17N3O/c1-11-3-4-12(2)14(9-11)17-15(18(19)22)10-16(21-17)13-5-7-20-8-6-13/h3-10,21H,1-2H3,(H2,19,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187230(US9670191, A21)
Show SMILES Cc1ccc(cc1C)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C18H17N3O/c1-11-3-4-14(9-12(11)2)17-15(18(19)22)10-16(21-17)13-5-7-20-8-6-13/h3-10,21H,1-2H3,(H2,19,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187231(US9670191, A22)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1[N+]#[C-])-c1ccncc1
Show InChI InChI=1S/C17H12N4O/c1-19-14-5-3-2-4-12(14)16-13(17(18)22)10-15(21-16)11-6-8-20-9-7-11/h2-10,21H,(H2,18,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329461(2-(3-Cyano-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(c1)C#N)-c1ccncc1
Show InChI InChI=1S/C17H12N4O/c18-10-11-2-1-3-13(8-11)16-14(17(19)22)9-15(21-16)12-4-6-20-7-5-12/h1-9,21H,(H2,19,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187233(US9670191, A24)
Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C21H23N5O/c1-25-10-12-26(13-11-25)17-4-2-16(3-5-17)20-18(21(22)27)14-19(24-20)15-6-8-23-9-7-15/h2-9,14,24H,10-13H2,1H3,(H2,22,27)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187234(US9670191, A25)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(c1)N1CCOCC1)-c1ccncc1
Show InChI InChI=1S/C20H20N4O2/c21-20(25)17-13-18(14-4-6-22-7-5-14)23-19(17)15-2-1-3-16(12-15)24-8-10-26-11-9-24/h1-7,12-13,23H,8-11H2,(H2,21,25)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187235(US9670191, A26)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(cc1)N1CCOCC1)-c1ccncc1
Show InChI InChI=1S/C20H20N4O2/c21-20(25)17-13-18(14-5-7-22-8-6-14)23-19(17)15-1-3-16(4-2-15)24-9-11-26-12-10-24/h1-8,13,23H,9-12H2,(H2,21,25)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187236(US9670191, A27)
Show SMILES CC(C)(C)OC(=O)N1CCc2ccc(cc2C1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C24H26N4O3/c1-24(2,3)31-23(30)28-11-8-15-4-5-17(12-18(15)14-28)21-19(22(25)29)13-20(27-21)16-6-9-26-10-7-16/h4-7,9-10,12-13,27H,8,11,14H2,1-3H3,(H2,25,29)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187237(US9670191, A28)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc2CCNCc2c1)-c1ccncc1
Show InChI InChI=1S/C19H18N4O/c20-19(24)16-10-17(13-4-6-21-7-5-13)23-18(16)14-2-1-12-3-8-22-11-15(12)9-14/h1-2,4-7,9-10,22-23H,3,8,11H2,(H2,20,24)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187238(US9670191, A29)
Show SMILES CN1CCc2ccc(cc2C1)-c1[nH]c(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C20H20N4O/c1-24-9-6-13-2-3-15(10-16(13)12-24)19-17(20(21)25)11-18(23-19)14-4-7-22-8-5-14/h2-5,7-8,10-11,23H,6,9,12H2,1H3,(H2,21,25)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187239(US9670191, B1)
Show SMILES Cc1c([nH]c(c1C(N)=O)-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C17H15N3O/c1-11-14(17(18)21)16(12-5-3-2-4-6-12)20-15(11)13-7-9-19-10-8-13/h2-10,20H,1H3,(H2,18,21)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329434(2,5-Dipyridin-4-yl-1H-pyrrole-3-carboxamide | CHEM...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccncc1)-c1ccncc1
Show InChI InChI=1S/C15H12N4O/c16-15(20)12-9-13(10-1-5-17-6-2-10)19-14(12)11-3-7-18-8-4-11/h1-9,19H,(H2,16,20)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187243(US9670191, D1)
Show SMILES CCn1c(cc(C(N)=O)c1-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C18H17N3O/c1-2-21-16(13-8-10-20-11-9-13)12-15(18(19)22)17(21)14-6-4-3-5-7-14/h3-12H,2H2,1H3,(H2,19,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187245(US9670191, E2)
Show SMILES Cc1ccccc1-c1[nH]c(cc1C(N)=O)-c1ccncc1F
Show InChI InChI=1S/C17H14FN3O/c1-10-4-2-3-5-11(10)16-13(17(19)22)8-15(21-16)12-6-7-20-9-14(12)18/h2-9,21H,1H3,(H2,19,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187247(US9670191, F2)
Show SMILES Cc1ccccc1-c1[nH]c(cc1C(N)=O)-c1ccnc(N)n1
Show InChI InChI=1S/C16H15N5O/c1-9-4-2-3-5-10(9)14-11(15(17)22)8-13(20-14)12-6-7-19-16(18)21-12/h2-8,20H,1H3,(H2,17,22)(H2,18,19,21)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187248(US9670191, F3)
Show SMILES CCc1ccccc1-c1[nH]c(cc1C(N)=O)-c1ccnc(N)n1
Show InChI InChI=1S/C17H17N5O/c1-2-10-5-3-4-6-11(10)15-12(16(18)23)9-14(21-15)13-7-8-20-17(19)22-13/h3-9,21H,2H2,1H3,(H2,18,23)(H2,19,20,22)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187249(US9670191, F4)
Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1F)-c1ccnc(N)n1
Show InChI InChI=1S/C15H12FN5O/c16-10-4-2-1-3-8(10)13-9(14(17)22)7-12(20-13)11-5-6-19-15(18)21-11/h1-7,20H,(H2,17,22)(H2,18,19,21)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329452(5-(2-Amino-pyrimidin-4-yl)-2-naphthalen-1-yl-1H-py...)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc2ccccc12)-c1ccnc(N)n1
Show InChI InChI=1S/C19H15N5O/c20-18(25)14-10-16(15-8-9-22-19(21)24-15)23-17(14)13-7-3-5-11-4-1-2-6-12(11)13/h1-10,23H,(H2,20,25)(H2,21,22,24)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM50329448(5-(2-Amino-pyrimidin-4-yl)-2-naphthalen-2-yl-1H-py...)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc2ccccc2c1)-c1ccnc(N)n1
Show InChI InChI=1S/C19H15N5O/c20-18(25)14-10-16(15-7-8-22-19(21)24-15)23-17(14)13-6-5-11-3-1-2-4-12(11)9-13/h1-10,23H,(H2,20,25)(H2,21,22,24)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187400(US9670191, F7)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(Oc2ccccc2)cc1)-c1ccnc(N)n1
Show InChI InChI=1S/C21H17N5O2/c22-20(27)16-12-18(17-10-11-24-21(23)26-17)25-19(16)13-6-8-15(9-7-13)28-14-4-2-1-3-5-14/h1-12,25H,(H2,22,27)(H2,23,24,26)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences srl

US Patent
LigandPNGBDBM187479(US9670191, F8)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(cc1)-c1ccccc1)-c1ccnc(N)n1
Show InChI InChI=1S/C21H17N5O/c22-20(27)16-12-18(17-10-11-24-21(23)26-17)25-19(16)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12,25H,(H2,22,27)(H2,23,24,26)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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