Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with all data for entry = 14
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene Corporation

LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataIC50:  60nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene Corporation

LigandPNGBDBM65456(19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)is...)
Affinity DataIC50:  1.20E+3nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Celgene Corporation

LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)
Affinity DataIC50:  1.50E+3nMpH: 7.0Assay Description:The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...More data for this Ligand-Target Pair