Compile Data Set for Download or QSAR
Found 277 Enz. Inhib. hit(s) with all data for entry = 2987
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387452(N3-(3-Chloro-4- fluorophenyl)- 5-methoxy-7- methyl...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(C)n1
Show InChI InChI=1S/C15H13ClFN3O2/c1-7-14-9(6-12(19-7)21-2)13(15(18)22-14)20-8-3-4-11(17)10(16)5-8/h3-6,20H,18H2,1-2H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387576(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES COCCNC(=O)c1ccc(cc1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C23H20ClFN4O3/c1-31-11-10-28-23(30)14-4-2-13(3-5-14)19-21-16(8-9-27-19)20(22(26)32-21)29-15-6-7-18(25)17(24)12-15/h2-9,12,29H,10-11,26H2,1H3,(H,28,30)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387577(N3-(3-chloro-4- fluorophenyl)- 7-(3,4- difluorophe...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccc(F)c(F)c1
Show InChI InChI=1S/C19H11ClF3N3O/c20-12-8-10(2-4-13(12)21)26-17-11-5-6-25-16(18(11)27-19(17)24)9-1-3-14(22)15(23)7-9/h1-8,26H,24H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387578(N3-(3-Chloro-4- fluorophenyl)- 7-(2,3,4- trifluoro...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccc(F)c(F)c1F
Show InChI InChI=1S/C19H10ClF4N3O/c20-11-7-8(1-3-12(11)21)27-17-10-5-6-26-16(18(10)28-19(17)25)9-2-4-13(22)15(24)14(9)23/h1-7,27H,25H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387579(7-Bromo-N3-(3- chloro-4- fluorophenyl)- 5-methoxy-...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(Br)n1
Show InChI InChI=1S/C14H10BrClFN3O2/c1-21-10-5-7-11(14(18)22-12(7)13(15)20-10)19-6-2-3-9(17)8(16)4-6/h2-5,19H,18H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387580(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)-5...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(n1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C21H14ClFN4O2/c1-28-17-9-14-19(26-13-6-7-16(23)15(22)8-13)21(25)29-20(14)18(27-17)12-4-2-11(10-24)3-5-12/h2-9,26H,25H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387581(N3-(3-chloro-4- fluorophenyl)- 7-(4- fluorophenyl)...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C20H14ClF2N3O2/c1-27-16-9-13-18(25-12-6-7-15(23)14(21)8-12)20(24)28-19(13)17(26-16)10-2-4-11(22)5-3-10/h2-9,25H,24H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387582(4-(2-amino-3- ((3-chloro-4- fluorophenyl) amino)-5...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(n1)-c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C21H16ClFN4O3/c1-29-16-9-13-18(26-12-6-7-15(23)14(22)8-12)21(25)30-19(13)17(27-16)10-2-4-11(5-3-10)20(24)28/h2-9,26H,25H2,1H3,(H2,24,28)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387585(N3-(3-chloro-4- fluorophenyl)- 7-fluorofuro [2,3-c...)
Show SMILES Nc1oc2c(F)nccc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H8ClF2N3O/c14-8-5-6(1-2-9(8)15)19-10-7-3-4-18-12(16)11(7)20-13(10)17/h1-5,19H,17H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387586(5-Chloro-N3- (3-chloro-4- fluorophenyl) furo[2,3-c...)
Show SMILES Nc1oc2cnc(Cl)cc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H8Cl2FN3O/c14-8-3-6(1-2-9(8)16)19-12-7-4-11(15)18-5-10(7)20-13(12)17/h1-5,19H,17H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387587(N3-(3-chloro-4- fluorophenyl)- 6-nitrobenzo- furan...)
Show SMILES Nc1oc2cc(ccc2c1Nc1ccc(F)c(Cl)c1)[N+]([O-])=O
Show InChI InChI=1S/C14H9ClFN3O3/c15-10-5-7(1-4-11(10)16)18-13-9-3-2-8(19(20)21)6-12(9)22-14(13)17/h1-6,18H,17H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387588(N3-(3-Chloro-4- fluorophenyl)- 5-fluoro-7- (pyridi...)
Show SMILES Nc1oc2c(nc(F)cc2c1Nc1ccc(F)c(Cl)c1)-c1ccncc1
Show InChI InChI=1S/C18H11ClF2N4O/c19-12-7-10(1-2-13(12)20)24-16-11-8-14(21)25-15(17(11)26-18(16)22)9-3-5-23-6-4-9/h1-8,24H,22H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387589(N3-(3-Chloro-4- fluorophenyl)- 5-fluorofuro [2,3-c...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H8ClF2N3O/c14-8-3-6(1-2-9(8)15)19-12-7-4-11(16)18-5-10(7)20-13(12)17/h1-5,19H,17H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387590(2-Amino-3-((2- chlorophenyl) amino)furo [2,3-c]pyr...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccccc1Cl)C#N
Show InChI InChI=1S/C14H9ClN4O/c15-9-3-1-2-4-10(9)19-12-8-5-6-18-11(7-16)13(8)20-14(12)17/h1-6,19H,17H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387591(2-Amino-3- ((4-fluoro-3- (trifluoro- methyl)phenyl...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(c1)C(F)(F)F)C#N
Show InChI InChI=1S/C15H8F4N4O/c16-10-2-1-7(5-9(10)15(17,18)19)23-12-8-3-4-22-11(6-20)13(8)24-14(12)21/h1-5,23H,21H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387592(N3-(3,4- difluoro- phenyl)-7- (pyridin-4- yl)furo[...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(F)c1)-c1ccncc1
Show InChI InChI=1S/C18H12F2N4O/c19-13-2-1-11(9-14(13)20)24-16-12-5-8-23-15(17(12)25-18(16)21)10-3-6-22-7-4-10/h1-9,24H,21H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387603(N3-(3,4- Difluoro- phenyl)-5- fluoro-7- (pyridin-4...)
Show SMILES Nc1oc2c(nc(F)cc2c1Nc1ccc(F)c(F)c1)-c1ccncc1
Show InChI InChI=1S/C18H11F3N4O/c19-12-2-1-10(7-13(12)20)24-16-11-8-14(21)25-15(17(11)26-18(16)22)9-3-5-23-6-4-9/h1-8,24H,22H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387605(7-Fluoro-N3- (4-fluoro-3- (trifluoro- methyl)pheny...)
Show SMILES Nc1oc2c(F)nccc2c1Nc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H8F5N3O/c15-9-2-1-6(5-8(9)14(17,18)19)22-10-7-3-4-21-12(16)11(7)23-13(10)20/h1-5,22H,20H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387606(N3-(3-Chloro-4- fluorophenyl)- 5,7-difluoro- furo[...)
Show SMILES Nc1oc2c(F)nc(F)cc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H7ClF3N3O/c14-7-3-5(1-2-8(7)15)19-10-6-4-9(16)20-12(17)11(6)21-13(10)18/h1-4,19H,18H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387607(N3-(3-Chloro-4- fluorophenyl)- 7-(2,6- difluoro- p...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1cc(F)nc(F)c1
Show InChI InChI=1S/C18H10ClF3N4O/c19-11-7-9(1-2-12(11)20)25-16-10-3-4-24-15(17(10)27-18(16)23)8-5-13(21)26-14(22)6-8/h1-7,25H,23H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387608(N3-(4-Fluoro-3- (trifluoro- methyl)phenyl)- 7-(pyr...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(c1)C(F)(F)F)-c1ccncc1
Show InChI InChI=1S/C19H12F4N4O/c20-14-2-1-11(9-13(14)19(21,22)23)27-16-12-5-8-26-15(17(12)28-18(16)24)10-3-6-25-7-4-10/h1-9,27H,24H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387611(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C20H15ClFN5O2/c1-24-20(28)15-8-10(4-6-25-15)16-18-12(5-7-26-16)17(19(23)29-18)27-11-2-3-14(22)13(21)9-11/h2-9,27H,23H2,1H3,(H,24,28)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387613(7-(2- Chlorophenyl)- N3-(3,4- difluorophenyl) furo...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(F)c1)-c1ccccc1Cl
Show InChI InChI=1S/C19H12ClF2N3O/c20-13-4-2-1-3-11(13)16-18-12(7-8-24-16)17(19(23)26-18)25-10-5-6-14(21)15(22)9-10/h1-9,25H,23H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387614(N3-(3,4- Difluoro- phenyl)-7-(2- methylpyridin- 4-...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(F)c3)c(N)oc12
Show InChI InChI=1S/C19H14F2N4O/c1-10-8-11(4-6-23-10)16-18-13(5-7-24-16)17(19(22)26-18)25-12-2-3-14(20)15(21)9-12/h2-9,25H,22H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387615(N3-(3-Chloro-4- fluorophenyl)- 7-(3- (trifluoro- m...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H12ClF4N3O/c21-14-9-12(4-5-15(14)22)28-17-13-6-7-27-16(18(13)29-19(17)26)10-2-1-3-11(8-10)20(23,24)25/h1-9,28H,26H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387617(N3-(4- Fluorophenyl)- 7-(pyridin-4- yl)furo[2,3- c...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)cc1)-c1ccncc1
Show InChI InChI=1S/C18H13FN4O/c19-12-1-3-13(4-2-12)23-16-14-7-10-22-15(17(14)24-18(16)20)11-5-8-21-9-6-11/h1-10,23H,20H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387618(N3-(2- Chlorophenyl)- 7-(pyridin-4- yl)furo[2,3- c...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccccc1Cl)-c1ccncc1
Show InChI InChI=1S/C18H13ClN4O/c19-13-3-1-2-4-14(13)23-16-12-7-10-22-15(17(12)24-18(16)20)11-5-8-21-9-6-11/h1-10,23H,20H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387619(7-(Pyridin-4- yl)-N3-(3- (trifluoro- methyl)phenyl...)
Show SMILES Nc1oc2c(nccc2c1Nc1cccc(c1)C(F)(F)F)-c1ccncc1
Show InChI InChI=1S/C19H13F3N4O/c20-19(21,22)12-2-1-3-13(10-12)26-16-14-6-9-25-15(17(14)27-18(16)23)11-4-7-24-8-5-11/h1-10,26H,23H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387620(N3-(3-Chloro-4- fluorophenyl)- 7-(naphthalen- 1-yl...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1cccc2ccccc12
Show InChI InChI=1S/C23H15ClFN3O/c24-18-12-14(8-9-19(18)25)28-21-17-10-11-27-20(22(17)29-23(21)26)16-7-3-5-13-4-1-2-6-15(13)16/h1-12,28H,26H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387621(N3-(4-fluoro- 3-(trifluoro- methyl)phenyl)- 7-(2-m...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(c3)C(F)(F)F)c(N)oc12
Show InChI InChI=1S/C20H14F4N4O/c1-10-8-11(4-6-26-10)16-18-13(5-7-27-16)17(19(25)29-18)28-12-2-3-15(21)14(9-12)20(22,23)24/h2-9,28H,25H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387623(N3-(2- chlorophenyl)- 7-(2-methyl- pyridin-4-yl) f...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3ccccc3Cl)c(N)oc12
Show InChI InChI=1S/C19H15ClN4O/c1-11-10-12(6-8-22-11)16-18-13(7-9-23-16)17(19(21)25-18)24-15-5-3-2-4-14(15)20/h2-10,24H,21H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387624(7-(2- methylpyridin- 4-yl)-N3-(3- (trifluoro- meth...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3cccc(c3)C(F)(F)F)c(N)oc12
Show InChI InChI=1S/C20H15F3N4O/c1-11-9-12(5-7-25-11)16-18-15(6-8-26-16)17(19(24)28-18)27-14-4-2-3-13(10-14)20(21,22)23/h2-10,27H,24H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387625(N3-(4- fluorophenyl)- 7-(2- methylpyridin- 4-yl)fu...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3ccc(F)cc3)c(N)oc12
Show InChI InChI=1S/C19H15FN4O/c1-11-10-12(6-8-22-11)16-18-15(7-9-23-16)17(19(21)25-18)24-14-4-2-13(20)3-5-14/h2-10,24H,21H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387627(7-Bromo-N3- (3-chloro-4- fluorophenyl) benzo[b] th...)
Show SMILES Nc1sc2c(Br)cccc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C14H9BrClFN2S/c15-9-3-1-2-8-12(14(18)20-13(8)9)19-7-4-5-11(17)10(16)6-7/h1-6,19H,18H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387628(N3-(3,4- Difluorophenyl) benzo[b] thiophene-2,3- d...)
Show SMILES Nc1sc2ccccc2c1Nc1ccc(F)c(F)c1
Show InChI InChI=1S/C14H10F2N2S/c15-10-6-5-8(7-11(10)16)18-13-9-3-1-2-4-12(9)19-14(13)17/h1-7,18H,17H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387629(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)be...)
Show SMILES Nc1sc2c(cccc2c1Nc1ccc(F)c(Cl)c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C21H13ClFN3S/c22-17-10-14(8-9-18(17)23)26-19-16-3-1-2-15(20(16)27-21(19)25)13-6-4-12(11-24)5-7-13/h1-10,26H,25H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387630(N3-(3-Chloro-4- fluorophenyl)- 7-(pyridin-4- yl)be...)
Show SMILES Nc1sc2c(cccc2c1Nc1ccc(F)c(Cl)c1)-c1ccncc1
Show InChI InChI=1S/C19H13ClFN3S/c20-15-10-12(4-5-16(15)21)24-17-14-3-1-2-13(18(14)25-19(17)22)11-6-8-23-9-7-11/h1-10,24H,22H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387633(N3-(3,4- difluoro- phenyl)-5- fluorofuro [2,3-c] p...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1ccc(F)c(F)c1
Show InChI InChI=1S/C13H8F3N3O/c14-8-2-1-6(3-9(8)15)19-12-7-4-11(16)18-5-10(7)20-13(12)17/h1-5,19H,17H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387636(N3-(3- Chlorophenyl)- 7-(pyridin-4- yl)furo[2,3- c...)
Show SMILES Nc1oc2c(nccc2c1Nc1cccc(Cl)c1)-c1ccncc1
Show InChI InChI=1S/C18H13ClN4O/c19-12-2-1-3-13(10-12)23-16-14-6-9-22-15(17(14)24-18(16)20)11-4-7-21-8-5-11/h1-10,23H,20H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387638(4-(2-Amino-3- ((2- chlorophenyl) amino)furo[2,3- c...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccccc3Cl)c(N)oc12
Show InChI InChI=1S/C20H16ClN5O2/c1-23-20(27)15-10-11(6-8-24-15)16-18-12(7-9-25-16)17(19(22)28-18)26-14-5-3-2-4-13(14)21/h2-10,26H,22H2,1H3,(H,23,27)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387639(N3-(3- Chlorophenyl)- 5-fluorofuro [2,3-c]pyridine...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1cccc(Cl)c1
Show InChI InChI=1S/C13H9ClFN3O/c14-7-2-1-3-8(4-7)18-12-9-5-11(15)17-6-10(9)19-13(12)16/h1-6,18H,16H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387640(5-Fluoro-N3-(3- (trifluoro- methyl)phenyl) furo[2,...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C14H9F4N3O/c15-11-5-9-10(6-20-11)22-13(19)12(9)21-8-3-1-2-7(4-8)14(16,17)18/h1-6,21H,19H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387641(5-Fluoro-N-(4- fluoro-3- (trifluoro- methyl)phenyl...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H8F5N3O/c15-9-2-1-6(3-8(9)14(17,18)19)22-12-7-4-11(16)21-5-10(7)23-13(12)20/h1-5,22H,20H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387642(4-(2-Amino-3- ((3,4- difluorophenyl) amino)furo[2,...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(F)c3)c(N)oc12
Show InChI InChI=1S/C20H15F2N5O2/c1-24-20(28)15-8-10(4-6-25-15)16-18-12(5-7-26-16)17(19(23)29-18)27-11-2-3-13(21)14(22)9-11/h2-9,27H,23H2,1H3,(H,24,28)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387643(4-(2-Amino-3- ((4- fluorophenyl) amino)furo[2,3- c...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)cc3)c(N)oc12
Show InChI InChI=1S/C20H16FN5O2/c1-23-20(27)15-10-11(6-8-24-15)16-18-14(7-9-25-16)17(19(22)28-18)26-13-4-2-12(21)3-5-13/h2-10,26H,22H2,1H3,(H,23,27)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387644(4-(2-Amino-3- ((3- chlorophenyl) amino)furo[2,3- c...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3cccc(Cl)c3)c(N)oc12
Show InChI InChI=1S/C20H16ClN5O2/c1-23-20(27)15-9-11(5-7-24-15)16-18-14(6-8-25-16)17(19(22)28-18)26-13-4-2-3-12(21)10-13/h2-10,26H,22H2,1H3,(H,23,27)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387645(4-(2-Amino-3- ((3- (trifluoro- methyl)phenyl) amin...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3cccc(c3)C(F)(F)F)c(N)oc12
Show InChI InChI=1S/C21H16F3N5O2/c1-26-20(30)15-9-11(5-7-27-15)16-18-14(6-8-28-16)17(19(25)31-18)29-13-4-2-3-12(10-13)21(22,23)24/h2-10,29H,25H2,1H3,(H,26,30)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387646(4-(2-amino-3- ((4-fluoro-3- (trifluoro- methyl)phe...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(c3)C(F)(F)F)c(N)oc12
Show InChI InChI=1S/C21H15F4N5O2/c1-27-20(31)15-8-10(4-6-28-15)16-18-12(5-7-29-16)17(19(26)32-18)30-11-2-3-14(22)13(9-11)21(23,24)25/h2-9,30H,26H2,1H3,(H,27,31)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387647(5-Fluoro-N3-(4- fluorophenyl) furo[2,3-c] pyridine...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1ccc(F)cc1
Show InChI InChI=1S/C13H9F2N3O/c14-7-1-3-8(4-2-7)18-12-9-5-11(15)17-6-10(9)19-13(12)16/h1-6,18H,16H2
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
CURADEV PHARMA, PVT. LTD.

US Patent
LigandPNGBDBM387648(N3-(3-Chloro-4- fluorophenyl)- 7-(2- methoxy- pyri...)
Show SMILES COc1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C19H14ClFN4O2/c1-26-15-8-10(4-6-23-15)16-18-12(5-7-24-16)17(19(22)27-18)25-11-2-3-14(21)13(20)9-11/h2-9,25H,22H2,1H3
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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