Compile Data Set for Download or QSAR
Found 34 Enz. Inhib. hit(s) with all data for entry = 50003168
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467821(CHEMBL4282304)
Show SMILES Clc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C15H10ClNO3S/c16-11-7-5-10(6-8-11)9-13-15(18)12-3-1-2-4-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 250nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467824(CHEMBL4287165)
Show SMILES O=C1\C(NS(=O)(=O)c2ccccc12)=C\c1ccccc1
Show InChI InChI=1S/C15H11NO3S/c17-15-12-8-4-5-9-14(12)20(18,19)16-13(15)10-11-6-2-1-3-7-11/h1-10,16H/b13-10-
Affinity DataIC50: 660nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467822(CHEMBL4283809)
Show SMILES COc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C16H13NO4S/c1-21-12-6-4-5-11(9-12)10-14-16(18)13-7-2-3-8-15(13)22(19,20)17-14/h2-10,17H,1H3/b14-10-
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467825(CHEMBL4289564)
Show SMILES Oc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H11NO4S/c17-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)16-13/h1-9,16-17H/b13-9-
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467828(CHEMBL4294381)
Show SMILES COc1ccccc1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C16H13NO4S/c1-21-14-8-4-2-6-11(14)10-13-16(18)12-7-3-5-9-15(12)22(19,20)17-13/h2-10,17H,1H3/b13-10-
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467831(CHEMBL4287104)
Show SMILES Fc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C15H10FNO3S/c16-11-7-5-10(6-8-11)9-13-15(18)12-3-1-2-4-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467826(CHEMBL4276925)
Show SMILES Brc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C15H10BrNO3S/c16-11-7-5-10(6-8-11)9-13-15(18)12-3-1-2-4-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467829(CHEMBL4290987)
Show SMILES COc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C16H13NO4S/c1-21-12-8-6-11(7-9-12)10-14-16(18)13-4-2-3-5-15(13)22(19,20)17-14/h2-10,17H,1H3/b14-10-
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467832(CHEMBL4276768)
Show SMILES Fc1cccc(F)c1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C15H9F2NO3S/c16-11-5-3-6-12(17)10(11)8-13-15(19)9-4-1-2-7-14(9)22(20,21)18-13/h1-8,18H/b13-8-
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467824(CHEMBL4287165)
Show SMILES O=C1\C(NS(=O)(=O)c2ccccc12)=C\c1ccccc1
Show InChI InChI=1S/C15H11NO3S/c17-15-12-8-4-5-9-14(12)20(18,19)16-13(15)10-11-6-2-1-3-7-11/h1-10,16H/b13-10-
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467820(CHEMBL4280545)
Show SMILES Cc1ccccc1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C16H13NO3S/c1-11-6-2-3-7-12(11)10-14-16(18)13-8-4-5-9-15(13)21(19,20)17-14/h2-10,17H,1H3/b14-10-
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467830(CHEMBL4287568)
Show SMILES Brc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H10BrNO3S/c16-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467828(CHEMBL4294381)
Show SMILES COc1ccccc1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C16H13NO4S/c1-21-14-8-4-2-6-11(14)10-13-16(18)12-7-3-5-9-15(12)22(19,20)17-13/h2-10,17H,1H3/b13-10-
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467831(CHEMBL4287104)
Show SMILES Fc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C15H10FNO3S/c16-11-7-5-10(6-8-11)9-13-15(18)12-3-1-2-4-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467823(CHEMBL4279425)
Show SMILES Fc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H10FNO3S/c16-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467825(CHEMBL4289564)
Show SMILES Oc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H11NO4S/c17-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)16-13/h1-9,16-17H/b13-9-
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467826(CHEMBL4276925)
Show SMILES Brc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C15H10BrNO3S/c16-11-7-5-10(6-8-11)9-13-15(18)12-3-1-2-4-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467820(CHEMBL4280545)
Show SMILES Cc1ccccc1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C16H13NO3S/c1-11-6-2-3-7-12(11)10-14-16(18)13-8-4-5-9-15(13)21(19,20)17-14/h2-10,17H,1H3/b14-10-
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467819(CHEMBL4292898)
Show SMILES Clc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H10ClNO3S/c16-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467829(CHEMBL4290987)
Show SMILES COc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C16H13NO4S/c1-21-12-8-6-11(7-9-12)10-14-16(18)13-4-2-3-5-15(13)22(19,20)17-14/h2-10,17H,1H3/b14-10-
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467821(CHEMBL4282304)
Show SMILES Clc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C15H10ClNO3S/c16-11-7-5-10(6-8-11)9-13-15(18)12-3-1-2-4-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467827(CHEMBL4287345)
Show SMILES Clc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c(Cl)c1
Show InChI InChI=1S/C15H9Cl2NO3S/c16-10-6-5-9(12(17)8-10)7-13-15(19)11-3-1-2-4-14(11)22(20,21)18-13/h1-8,18H/b13-7-
Affinity DataIC50: 4.96E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467818(CHEMBL4280348)
Show SMILES Brc1ccccc1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C15H10BrNO3S/c16-12-7-3-1-5-10(12)9-13-15(18)11-6-2-4-8-14(11)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467823(CHEMBL4279425)
Show SMILES Fc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H10FNO3S/c16-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 9.93E+3nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467832(CHEMBL4276768)
Show SMILES Fc1cccc(F)c1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C15H9F2NO3S/c16-11-5-3-6-12(17)10(11)8-13-15(19)9-4-1-2-7-14(9)22(20,21)18-13/h1-8,18H/b13-8-
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1
Show InChI InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM18073((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...)
Show SMILES N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM18073((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...)
Show SMILES N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467822(CHEMBL4283809)
Show SMILES COc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C16H13NO4S/c1-21-12-6-4-5-11(9-12)10-14-16(18)13-7-2-3-8-15(13)22(19,20)17-14/h2-10,17H,1H3/b14-10-
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1
Show InChI InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467827(CHEMBL4287345)
Show SMILES Clc1ccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c(Cl)c1
Show InChI InChI=1S/C15H9Cl2NO3S/c16-10-6-5-9(12(17)8-10)7-13-15(19)11-3-1-2-4-14(11)22(20,21)18-13/h1-8,18H/b13-7-
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467818(CHEMBL4280348)
Show SMILES Brc1ccccc1\C=C1/NS(=O)(=O)c2ccccc2C1=O
Show InChI InChI=1S/C15H10BrNO3S/c16-12-7-3-1-5-10(12)9-13-15(18)11-6-2-4-8-14(11)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467830(CHEMBL4287568)
Show SMILES Brc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H10BrNO3S/c16-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50467819(CHEMBL4292898)
Show SMILES Clc1cccc(\C=C2/NS(=O)(=O)c3ccccc3C2=O)c1
Show InChI InChI=1S/C15H10ClNO3S/c16-11-5-3-4-10(8-11)9-13-15(18)12-6-1-2-7-14(12)21(19,20)17-13/h1-9,17H/b13-9-
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human TNAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by su...More data for this Ligand-Target Pair