Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for entry = 50003718
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50475205(CHEMBL190899)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)
Affinity DataIC50:  34nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50088570((S)-2-(3-Benzoyl-phenyl)-propionic acid | (S)-2-(3...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50475204(CHEMBL192943)
Affinity DataIC50:  80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed