Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for entry = 50004515
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche Pomezia

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
Affinity DataIC50: 79nMAssay Description:Inhibition of HDAC in human HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche Pomezia

Curated by ChEMBL
LigandPNGBDBM50483618(CHEMBL1760915)
Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C17H25N3O3/c21-16(19-23)8-4-7-14-9-11-20(12-10-14)17(22)18-13-15-5-2-1-3-6-15/h1-3,5-6,14,23H,4,7-13H2,(H,18,22)(H,19,21)
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC in human HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche Pomezia

Curated by ChEMBL
LigandPNGBDBM50483617(CHEMBL1760914)
Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C16H23N3O3/c20-15(18-22)8-4-5-13-9-11-19(12-10-13)16(21)17-14-6-2-1-3-7-14/h1-3,6-7,13,22H,4-5,8-12H2,(H,17,21)(H,18,20)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC in human HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche Pomezia

Curated by ChEMBL
LigandPNGBDBM50483619(CHEMBL1760913)
Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)Cc1ccccc1
Show InChI InChI=1S/C17H24N2O3/c20-16(18-22)8-4-7-14-9-11-19(12-10-14)17(21)13-15-5-2-1-3-6-15/h1-3,5-6,14,22H,4,7-13H2,(H,18,20)
Affinity DataIC50: 260nMAssay Description:Inhibition of HDAC in human HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche Pomezia

Curated by ChEMBL
LigandPNGBDBM50483615(CHEMBL1760911)
Show SMILES ONC(=O)CCCC1CCN(CC1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C15H22N2O4S/c18-15(16-19)8-4-5-13-9-11-17(12-10-13)22(20,21)14-6-2-1-3-7-14/h1-3,6-7,13,19H,4-5,8-12H2,(H,16,18)
Affinity DataIC50: 540nMAssay Description:Inhibition of HDAC in human HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche Pomezia

Curated by ChEMBL
LigandPNGBDBM50483614(CHEMBL1760910)
Show SMILES ONC(=O)CCCC1CCN(CC1)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C16H24N2O4S/c19-16(17-20)8-4-7-14-9-11-18(12-10-14)23(21,22)13-15-5-2-1-3-6-15/h1-3,5-6,14,20H,4,7-13H2,(H,17,19)
Affinity DataIC50: 840nMAssay Description:Inhibition of HDAC in human HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche Pomezia

Curated by ChEMBL
LigandPNGBDBM50483616(CHEMBL1760912)
Show SMILES ONC(=O)CCCC1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C16H22N2O3/c19-15(17-21)8-4-5-13-9-11-18(12-10-13)16(20)14-6-2-1-3-7-14/h1-3,6-7,13,21H,4-5,8-12H2,(H,17,19)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of HDAC in human HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid