Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with all data for entry = 50005250
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
Show SMILES CC(C)C1=C(SC2=N[C@](C)([C@H](N12)c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1CC[C@H]1C(=O)N(C)C
Show InChI InChI=1S/C28H30Cl2N4O2S/c1-16(2)22-23(26(36)33-15-14-21(33)25(35)32(4)5)37-27-31-28(3,18-8-12-20(30)13-9-18)24(34(22)27)17-6-10-19(29)11-7-17/h6-13,16,21,24H,14-15H2,1-5H3/t21-,24+,28-/m0/s1
Affinity DataIC50: 140nMAssay Description:Inhibition of human His-tagged p53 (1 to 132 amino acid residues)/GST-tagged MDM2 L33E mutant (25 to 108 amino acid residues) interaction by HTRF ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid