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Found 26 Enz. Inhib. hit(s) with all data for entry = 50008086
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515528(CHEMBL4459518)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515536(CHEMBL4577957)
Affinity DataIC50:  760nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515538(CHEMBL4562297)
Affinity DataIC50:  820nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515538(CHEMBL4562297)
Affinity DataIC50:  930nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515528(CHEMBL4459518)
Affinity DataIC50:  960nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515537(CHEMBL4589636)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515536(CHEMBL4577957)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515537(CHEMBL4589636)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515527(CHEMBL4451049)
Affinity DataIC50:  3.12E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515531(CHEMBL4452177)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515527(CHEMBL4451049)
Affinity DataIC50:  5.28E+3nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515531(CHEMBL4452177)
Affinity DataIC50:  6.61E+3nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515528(CHEMBL4459518)
Affinity DataIC50:  7.26E+3nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515537(CHEMBL4589636)
Affinity DataIC50:  8.58E+3nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515536(CHEMBL4577957)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515538(CHEMBL4562297)
Affinity DataIC50:  1.74E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515529(CHEMBL4544484)
Affinity DataIC50:  2.93E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515534(CHEMBL4465914)
Affinity DataIC50:  3.05E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515531(CHEMBL4452177)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50462013(CHEBI:8241 | Piplartine)
Affinity DataIC50:  4.59E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515527(CHEMBL4451049)
Affinity DataIC50:  5.12E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515532(CHEMBL4515694)
Affinity DataIC50:  7.66E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515533(CHEMBL4460514)
Affinity DataIC50:  8.16E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515539(CHEMBL4443061)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515535(CHEMBL4439743)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50515530(CHEMBL4447931)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed