Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50011135
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  11nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50429461(CHEMBL2332369)
Affinity DataIC50:  33nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  50nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  63nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  66nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  72nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  88nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50429461(CHEMBL2332369)
Affinity DataIC50:  100nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  141nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  178nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  303nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  319nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  378nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  608nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  623nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  657nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  709nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  806nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  921nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  3.95E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  4.86E+3nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  4.93E+3nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  6.88E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed