Found 35 Enz. Inhib. hit(s) with all data for entry = 50012311 TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 1.26E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataKd: 7.28E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 2.57E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 9.30E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 410nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 7.31E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 430nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 17nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 1.06E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 370nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 180nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 410nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 1.37E+4nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 2.72E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 790nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 8.50E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataKd: 3.82E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataKd: 8.93E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 1.76E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
