Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with all data for entry = 50012591
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558629(CHEMBL4779552)
Show SMILES COc1ccc(cc1OC)-c1cc(n2nc(cc2n1)-c1ccc(Br)s1)C(F)(F)F
Show InChI InChI=1S/C19H13BrF3N3O2S/c1-27-13-4-3-10(7-14(13)28-2)11-8-16(19(21,22)23)26-18(24-11)9-12(25-26)15-5-6-17(20)29-15/h3-9H,1-2H3
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558621(CHEMBL4756599)
Show SMILES COc1ccc(cc1OC)-c1cc(n2nc(cc2n1)-c1cccs1)C(F)(F)F
Show InChI InChI=1S/C19H14F3N3O2S/c1-26-14-6-5-11(8-15(14)27-2)12-9-17(19(20,21)22)25-18(23-12)10-13(24-25)16-4-3-7-28-16/h3-10H,1-2H3
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558630(CHEMBL4759937)
Show SMILES COc1ccc(cc1OC)-c1cc(n2nc(cc2n1)-c1ccc(Cl)s1)C(F)(F)F
Show InChI InChI=1S/C19H13ClF3N3O2S/c1-27-13-4-3-10(7-14(13)28-2)11-8-16(19(21,22)23)26-18(24-11)9-12(25-26)15-5-6-17(20)29-15/h3-9H,1-2H3
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558621(CHEMBL4756599)
Show SMILES COc1ccc(cc1OC)-c1cc(n2nc(cc2n1)-c1cccs1)C(F)(F)F
Show InChI InChI=1S/C19H14F3N3O2S/c1-26-14-6-5-11(8-15(14)27-2)12-9-17(19(20,21)22)25-18(23-12)10-13(24-25)16-4-3-7-28-16/h3-10H,1-2H3
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human full length FUBP1 expressed in Escherichia coli BL21 DE3 assessed as reduction in FUBP1 interaction with FUSE p21 oligonucleotide...More data for this Ligand-Target Pair
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558622(CHEMBL4790431)
Show SMILES COc1cccc(c1)-c1cc(n2nc(cc2n1)-c1cccs1)C(F)(F)F
Show InChI InChI=1S/C18H12F3N3OS/c1-25-12-5-2-4-11(8-12)13-9-16(18(19,20)21)24-17(22-13)10-14(23-24)15-6-3-7-26-15/h2-10H,1H3
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558632(CHEMBL4752987)
Show SMILES COc1ccc(cc1OC)-c1cc(n2nc(cc2n1)-c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C22H18F3N3O2/c1-13-4-6-14(7-5-13)17-12-21-26-16(11-20(22(23,24)25)28(21)27-17)15-8-9-18(29-2)19(10-15)30-3/h4-12H,1-3H3
Affinity DataIC50: 8.48E+4nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558633(CHEMBL4763066)
Show SMILES COc1ccc(cc1OC)-c1cc(n2nc(cc2n1)-c1ccco1)C(F)(F)F
Show InChI InChI=1S/C19H14F3N3O3/c1-26-15-6-5-11(8-16(15)27-2)12-9-17(19(20,21)22)25-18(23-12)10-13(24-25)14-4-3-7-28-14/h3-10H,1-2H3
Affinity DataIC50: 8.51E+4nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558628(CHEMBL4783432)
Show SMILES FC(F)(F)c1cc(nc2cc(nn12)-c1cccs1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H9ClF3N3S/c18-11-5-3-10(4-6-11)12-8-15(17(19,20)21)24-16(22-12)9-13(23-24)14-2-1-7-25-14/h1-9H
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558626(CHEMBL1393159)
Show SMILES FC(F)(F)c1cc(nc2cc(nn12)-c1cccs1)-c1cccs1
Show InChI InChI=1S/C15H8F3N3S2/c16-15(17,18)13-7-9(11-3-1-5-22-11)19-14-8-10(20-21(13)14)12-4-2-6-23-12/h1-8H
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558625(CHEMBL4759898)
Show SMILES FC(F)(F)c1cc(nc2cc(nn12)-c1cccs1)-c1cccnc1
Show InChI InChI=1S/C16H9F3N4S/c17-16(18,19)14-7-11(10-3-1-5-20-9-10)21-15-8-12(22-23(14)15)13-4-2-6-24-13/h1-9H
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558624(CHEMBL4783747)
Show SMILES COc1ccc(cc1)-c1cc(n2nc(cc2n1)-c1cccs1)C(F)(F)F
Show InChI InChI=1S/C18H12F3N3OS/c1-25-12-6-4-11(5-7-12)13-9-16(18(19,20)21)24-17(22-13)10-14(23-24)15-3-2-8-26-15/h2-10H,1H3
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558623(CHEMBL4790064)
Show SMILES FC(F)(F)c1cc(nc2cc(nn12)-c1cccs1)-c1ccccc1
Show InChI InChI=1S/C17H10F3N3S/c18-17(19,20)15-9-12(11-5-2-1-3-6-11)21-16-10-13(22-23(15)16)14-7-4-8-24-14/h1-10H
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558627(CHEMBL4747112)
Show SMILES FC(F)(F)c1cc(nc2cc(nn12)-c1cccs1)-c1ccncc1
Show InChI InChI=1S/C16H9F3N4S/c17-16(18,19)14-8-11(10-3-5-20-6-4-10)21-15-9-12(22-23(14)15)13-2-1-7-24-13/h1-9H
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetFar upstream element-binding protein 1(Homo sapiens)
Institute for Tumor Biology and Experimental Therapy

Curated by ChEMBL
LigandPNGBDBM50558631(CHEMBL4764600)
Show SMILES COc1ccc(cc1OC)-c1cc(n2nc(cc2n1)C1CC1)C(F)(F)F
Show InChI InChI=1S/C18H16F3N3O2/c1-25-14-6-5-11(7-15(14)26-2)12-8-16(18(19,20)21)24-17(22-12)9-13(23-24)10-3-4-10/h5-10H,3-4H2,1-2H3
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid