Compile Data Set for Download or QSAR
Found 40 Enz. Inhib. hit(s) with all data for entry = 50013628
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511588(CHEMBL4453207)
Show SMILES COc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO3STe/c1-18-12-4-8-14(9-5-12)20-10-11-2-6-13(7-3-11)19(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  0.300nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511587(CHEMBL4532721)
Show SMILES Cc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO2STe/c1-11-2-8-14(9-3-11)19-10-12-4-6-13(7-5-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  0.540nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511590(CHEMBL4587627)
Show SMILES Cc1ccccc1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H15NO2STe/c1-11-4-2-3-5-14(11)19-10-12-6-8-13(9-7-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  0.670nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511590(CHEMBL4587627)
Show SMILES Cc1ccccc1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H15NO2STe/c1-11-4-2-3-5-14(11)19-10-12-6-8-13(9-7-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  0.760nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511588(CHEMBL4453207)
Show SMILES COc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO3STe/c1-18-12-4-8-14(9-5-12)20-10-11-2-6-13(7-3-11)19(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  1.5nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511590(CHEMBL4587627)
Show SMILES Cc1ccccc1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H15NO2STe/c1-11-4-2-3-5-14(11)19-10-12-6-8-13(9-7-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  1.80nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511587(CHEMBL4532721)
Show SMILES Cc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO2STe/c1-11-2-8-14(9-3-11)19-10-12-4-6-13(7-5-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511588(CHEMBL4453207)
Show SMILES COc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO3STe/c1-18-12-4-8-14(9-5-12)20-10-11-2-6-13(7-3-11)19(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511588(CHEMBL4453207)
Show SMILES COc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO3STe/c1-18-12-4-8-14(9-5-12)20-10-11-2-6-13(7-3-11)19(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  2.10nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511587(CHEMBL4532721)
Show SMILES Cc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO2STe/c1-11-2-8-14(9-3-11)19-10-12-4-6-13(7-5-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  2.20nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511585(CHEMBL4471819)
Show SMILES COc1cc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc(OC)c1OC
Show InChI InChI=1S/C16H19NO5STe/c1-20-14-8-13(9-15(21-2)16(14)22-3)24-10-11-4-6-12(7-5-11)23(17,18)19/h4-9H,10H2,1-3H3,(H2,17,18,19)
Affinity DataKi:  2.40nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511586(CHEMBL4436859)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccccc2)cc1
Show InChI InChI=1S/C13H13NO2STe/c14-17(15,16)12-8-6-11(7-9-12)10-18-13-4-2-1-3-5-13/h1-9H,10H2,(H2,14,15,16)
Affinity DataKi:  2.40nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511591(CHEMBL4453472)
Show SMILES Cc1cccc(C)c1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H17NO2STe/c1-11-4-3-5-12(2)15(11)20-10-13-6-8-14(9-7-13)19(16,17)18/h3-9H,10H2,1-2H3,(H2,16,17,18)
Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511590(CHEMBL4587627)
Show SMILES Cc1ccccc1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H15NO2STe/c1-11-4-2-3-5-14(11)19-10-12-6-8-13(9-7-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  2.60nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511588(CHEMBL4453207)
Show SMILES COc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO3STe/c1-18-12-4-8-14(9-5-12)20-10-11-2-6-13(7-3-11)19(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  2.60nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511591(CHEMBL4453472)
Show SMILES Cc1cccc(C)c1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H17NO2STe/c1-11-4-3-5-12(2)15(11)20-10-13-6-8-14(9-7-13)19(16,17)18/h3-9H,10H2,1-2H3,(H2,16,17,18)
Affinity DataKi:  2.70nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511589(CHEMBL4482933)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C17H15NO2STe/c18-21(19,20)16-8-5-13(6-9-16)12-22-17-10-7-14-3-1-2-4-15(14)11-17/h1-11H,12H2,(H2,18,19,20)
Affinity DataKi:  2.90nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511591(CHEMBL4453472)
Show SMILES Cc1cccc(C)c1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H17NO2STe/c1-11-4-3-5-12(2)15(11)20-10-13-6-8-14(9-7-13)19(16,17)18/h3-9H,10H2,1-2H3,(H2,16,17,18)
Affinity DataKi:  3.30nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511587(CHEMBL4532721)
Show SMILES Cc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO2STe/c1-11-2-8-14(9-3-11)19-10-12-4-6-13(7-5-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  4.40nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511591(CHEMBL4453472)
Show SMILES Cc1cccc(C)c1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H17NO2STe/c1-11-4-3-5-12(2)15(11)20-10-13-6-8-14(9-7-13)19(16,17)18/h3-9H,10H2,1-2H3,(H2,16,17,18)
Affinity DataKi:  5.10nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511586(CHEMBL4436859)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccccc2)cc1
Show InChI InChI=1S/C13H13NO2STe/c14-17(15,16)12-8-6-11(7-9-12)10-18-13-4-2-1-3-5-13/h1-9H,10H2,(H2,14,15,16)
Affinity DataKi:  8.40nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511586(CHEMBL4436859)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccccc2)cc1
Show InChI InChI=1S/C13H13NO2STe/c14-17(15,16)12-8-6-11(7-9-12)10-18-13-4-2-1-3-5-13/h1-9H,10H2,(H2,14,15,16)
Affinity DataKi:  12nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
Affinity DataKi:  12nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511585(CHEMBL4471819)
Show SMILES COc1cc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc(OC)c1OC
Show InChI InChI=1S/C16H19NO5STe/c1-20-14-8-13(9-15(21-2)16(14)22-3)24-10-11-4-6-12(7-5-11)23(17,18)19/h4-9H,10H2,1-3H3,(H2,17,18,19)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511590(CHEMBL4587627)
Show SMILES Cc1ccccc1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H15NO2STe/c1-11-4-2-3-5-14(11)19-10-12-6-8-13(9-7-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511587(CHEMBL4532721)
Show SMILES Cc1ccc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C14H15NO2STe/c1-11-2-8-14(9-3-11)19-10-12-4-6-13(7-5-12)18(15,16)17/h2-9H,10H2,1H3,(H2,15,16,17)
Affinity DataKi:  24nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
Affinity DataKi:  26nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511586(CHEMBL4436859)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccccc2)cc1
Show InChI InChI=1S/C13H13NO2STe/c14-17(15,16)12-8-6-11(7-9-12)10-18-13-4-2-1-3-5-13/h1-9H,10H2,(H2,14,15,16)
Affinity DataKi:  52nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511585(CHEMBL4471819)
Show SMILES COc1cc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc(OC)c1OC
Show InChI InChI=1S/C16H19NO5STe/c1-20-14-8-13(9-15(21-2)16(14)22-3)24-10-11-4-6-12(7-5-11)23(17,18)19/h4-9H,10H2,1-3H3,(H2,17,18,19)
Affinity DataKi:  55nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511589(CHEMBL4482933)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C17H15NO2STe/c18-21(19,20)16-8-5-13(6-9-16)12-22-17-10-7-14-3-1-2-4-15(14)11-17/h1-11H,12H2,(H2,18,19,20)
Affinity DataKi:  63nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
Affinity DataKi:  74nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511589(CHEMBL4482933)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C17H15NO2STe/c18-21(19,20)16-8-5-13(6-9-16)12-22-17-10-7-14-3-1-2-4-15(14)11-17/h1-11H,12H2,(H2,18,19,20)
Affinity DataKi:  182nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511586(CHEMBL4436859)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccccc2)cc1
Show InChI InChI=1S/C13H13NO2STe/c14-17(15,16)12-8-6-11(7-9-12)10-18-13-4-2-1-3-5-13/h1-9H,10H2,(H2,14,15,16)
Affinity DataKi:  210nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511591(CHEMBL4453472)
Show SMILES Cc1cccc(C)c1[Te]Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H17NO2STe/c1-11-4-3-5-12(2)15(11)20-10-13-6-8-14(9-7-13)19(16,17)18/h3-9H,10H2,1-2H3,(H2,16,17,18)
Affinity DataKi:  257nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511585(CHEMBL4471819)
Show SMILES COc1cc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc(OC)c1OC
Show InChI InChI=1S/C16H19NO5STe/c1-20-14-8-13(9-15(21-2)16(14)22-3)24-10-11-4-6-12(7-5-11)23(17,18)19/h4-9H,10H2,1-3H3,(H2,17,18,19)
Affinity DataKi:  377nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511589(CHEMBL4482933)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C17H15NO2STe/c18-21(19,20)16-8-5-13(6-9-16)12-22-17-10-7-14-3-1-2-4-15(14)11-17/h1-11H,12H2,(H2,18,19,20)
Affinity DataKi:  828nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511589(CHEMBL4482933)
Show SMILES NS(=O)(=O)c1ccc(C[Te]c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C17H15NO2STe/c18-21(19,20)16-8-5-13(6-9-16)12-22-17-10-7-14-3-1-2-4-15(14)11-17/h1-11H,12H2,(H2,18,19,20)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50511585(CHEMBL4471819)
Show SMILES COc1cc([Te]Cc2ccc(cc2)S(N)(=O)=O)cc(OC)c1OC
Show InChI InChI=1S/C16H19NO5STe/c1-20-14-8-13(9-15(21-2)16(14)22-3)24-10-11-4-6-12(7-5-11)23(17,18)19/h4-9H,10H2,1-3H3,(H2,17,18,19)
Affinity DataKi:  6.93E+3nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid