Compile Data Set for Download or QSAR
Found 334 Enz. Inhib. hit(s) with all data for entry = 50014168
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
Affinity DataKi:  0.339nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
Affinity DataKi:  0.780nMAssay Description:Binding affinity to 5HT5A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573235(CHEMBL4877603)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17ClN4/c15-12-4-1-3-11(9-12)14-13(10-17-18-14)19-7-2-5-16-6-8-19/h1,3-4,9-10,16H,2,5-8H2,(H,17,18)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573235(CHEMBL4877603)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17ClN4/c15-12-4-1-3-11(9-12)14-13(10-17-18-14)19-7-2-5-16-6-8-19/h1,3-4,9-10,16H,2,5-8H2,(H,17,18)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573233(CHEMBL4876193)
Show SMILES Cc1cccc(c1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C15H20N4/c1-12-4-2-5-13(10-12)15-14(11-17-18-15)19-8-3-6-16-7-9-19/h2,4-5,10-11,16H,3,6-9H2,1H3,(H,17,18)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573233(CHEMBL4876193)
Show SMILES Cc1cccc(c1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C15H20N4/c1-12-4-2-5-13(10-12)15-14(11-17-18-15)19-8-3-6-16-7-9-19/h2,4-5,10-11,16H,3,6-9H2,1H3,(H,17,18)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573248(CHEMBL4848305)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  16nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Show SMILES Clc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17ClN4/c15-12-4-2-11(3-5-12)14-13(10-17-18-14)19-8-1-6-16-7-9-19/h2-5,10,16H,1,6-9H2,(H,17,18)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Show SMILES Clc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17ClN4/c15-12-4-2-11(3-5-12)14-13(10-17-18-14)19-8-1-6-16-7-9-19/h2-5,10,16H,1,6-9H2,(H,17,18)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573248(CHEMBL4848305)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573248(CHEMBL4848305)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573237(CHEMBL4866412)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17FN4/c15-12-4-1-3-11(9-12)14-13(10-17-18-14)19-7-2-5-16-6-8-19/h1,3-4,9-10,16H,2,5-8H2,(H,17,18)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573249(CHEMBL4858338)
Show SMILES Clc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-10(2-4-11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573249(CHEMBL4858338)
Show SMILES Clc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-10(2-4-11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573237(CHEMBL4866412)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17FN4/c15-12-4-1-3-11(9-12)14-13(10-17-18-14)19-7-2-5-16-6-8-19/h1,3-4,9-10,16H,2,5-8H2,(H,17,18)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573253(CHEMBL4852622)
Show SMILES Cc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C14H18N4/c1-11-2-4-12(5-3-11)14-13(10-16-17-14)18-8-6-15-7-9-18/h2-5,10,15H,6-9H2,1H3,(H,16,17)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573253(CHEMBL4852622)
Show SMILES Cc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C14H18N4/c1-11-2-4-12(5-3-11)14-13(10-16-17-14)18-8-6-15-7-9-18/h2-5,10,15H,6-9H2,1H3,(H,16,17)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573234(CHEMBL4863868)
Show SMILES Cc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C15H20N4/c1-12-3-5-13(6-4-12)15-14(11-17-18-15)19-9-2-7-16-8-10-19/h3-6,11,16H,2,7-10H2,1H3,(H,17,18)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573234(CHEMBL4863868)
Show SMILES Cc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C15H20N4/c1-12-3-5-13(6-4-12)15-14(11-17-18-15)19-9-2-7-16-8-10-19/h3-6,11,16H,2,7-10H2,1H3,(H,17,18)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573238(CHEMBL4869695)
Show SMILES Fc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17FN4/c15-12-4-2-11(3-5-12)14-13(10-17-18-14)19-8-1-6-16-7-9-19/h2-5,10,16H,1,6-9H2,(H,17,18)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573238(CHEMBL4869695)
Show SMILES Fc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C14H17FN4/c15-12-4-2-11(3-5-12)14-13(10-17-18-14)19-8-1-6-16-7-9-19/h2-5,10,16H,1,6-9H2,(H,17,18)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573251(CHEMBL4856702)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  42nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573251(CHEMBL4856702)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573251(CHEMBL4856702)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573245(CHEMBL4877051)
Show SMILES COc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C14H18N4O/c1-19-12-4-2-11(3-5-12)14-13(10-16-17-14)18-8-6-15-7-9-18/h2-5,10,15H,6-9H2,1H3,(H,16,17)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573245(CHEMBL4877051)
Show SMILES COc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C14H18N4O/c1-19-12-4-2-11(3-5-12)14-13(10-16-17-14)18-8-6-15-7-9-18/h2-5,10,15H,6-9H2,1H3,(H,16,17)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573251(CHEMBL4856702)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  58nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573248(CHEMBL4848305)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  61nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573247(CHEMBL4859827)
Show SMILES Clc1ccccc1-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-4-2-1-3-10(11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573247(CHEMBL4859827)
Show SMILES Clc1ccccc1-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-4-2-1-3-10(11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573252(CHEMBL4871980)
Show SMILES Fc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-10(2-4-11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573252(CHEMBL4871980)
Show SMILES Fc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-10(2-4-11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573249(CHEMBL4858338)
Show SMILES Clc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-10(2-4-11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  75nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573248(CHEMBL4848305)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  76nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573246(CHEMBL4862745)
Show SMILES C1CN(CCN1)c1c[nH]nc1-c1ccccc1
Show InChI InChI=1S/C13H16N4/c1-2-4-11(5-3-1)13-12(10-15-16-13)17-8-6-14-7-9-17/h1-5,10,14H,6-9H2,(H,15,16)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573246(CHEMBL4862745)
Show SMILES C1CN(CCN1)c1c[nH]nc1-c1ccccc1
Show InChI InChI=1S/C13H16N4/c1-2-4-11(5-3-1)13-12(10-15-16-13)17-8-6-14-7-9-17/h1-5,10,14H,6-9H2,(H,15,16)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573250(CHEMBL4874854)
Show SMILES Fc1ccccc1-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-4-2-1-3-10(11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573250(CHEMBL4874854)
Show SMILES Fc1ccccc1-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-4-2-1-3-10(11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573248(CHEMBL4848305)
Show SMILES Clc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  109nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573253(CHEMBL4852622)
Show SMILES Cc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C14H18N4/c1-11-2-4-12(5-3-11)14-13(10-16-17-14)18-8-6-15-7-9-18/h2-5,10,15H,6-9H2,1H3,(H,16,17)
Affinity DataKi:  118nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573249(CHEMBL4858338)
Show SMILES Clc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15ClN4/c14-11-3-1-10(2-4-11)13-12(9-16-17-13)18-7-5-15-6-8-18/h1-4,9,15H,5-8H2,(H,16,17)
Affinity DataKi:  121nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573245(CHEMBL4877051)
Show SMILES COc1ccc(cc1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C14H18N4O/c1-19-12-4-2-11(3-5-12)14-13(10-16-17-14)18-8-6-15-7-9-18/h2-5,10,15H,6-9H2,1H3,(H,16,17)
Affinity DataKi:  126nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573246(CHEMBL4862745)
Show SMILES C1CN(CCN1)c1c[nH]nc1-c1ccccc1
Show InChI InChI=1S/C13H16N4/c1-2-4-11(5-3-1)13-12(10-15-16-13)17-8-6-14-7-9-17/h1-5,10,14H,6-9H2,(H,15,16)
Affinity DataKi:  141nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573241(CHEMBL4863036)
Show SMILES COc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C15H20N4O/c1-20-13-5-3-12(4-6-13)15-14(11-17-18-15)19-9-2-7-16-8-10-19/h3-6,11,16H,2,7-10H2,1H3,(H,17,18)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573241(CHEMBL4863036)
Show SMILES COc1ccc(cc1)-c1n[nH]cc1N1CCCNCC1
Show InChI InChI=1S/C15H20N4O/c1-20-13-5-3-12(4-6-13)15-14(11-17-18-15)19-9-2-7-16-8-10-19/h3-6,11,16H,2,7-10H2,1H3,(H,17,18)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573251(CHEMBL4856702)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  162nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573246(CHEMBL4862745)
Show SMILES C1CN(CCN1)c1c[nH]nc1-c1ccccc1
Show InChI InChI=1S/C13H16N4/c1-2-4-11(5-3-1)13-12(10-15-16-13)17-8-6-14-7-9-17/h1-5,10,14H,6-9H2,(H,15,16)
Affinity DataKi:  185nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573251(CHEMBL4856702)
Show SMILES Fc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C13H15FN4/c14-11-3-1-2-10(8-11)13-12(9-16-17-13)18-6-4-15-5-7-18/h1-3,8-9,15H,4-7H2,(H,16,17)
Affinity DataKi:  215nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573244(CHEMBL4870675)
Show SMILES COc1cccc(c1)-c1n[nH]cc1N1CCNCC1
Show InChI InChI=1S/C14H18N4O/c1-19-12-4-2-3-11(9-12)14-13(10-16-17-14)18-7-5-15-6-8-18/h2-4,9-10,15H,5-8H2,1H3,(H,16,17)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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