Compile Data Set for Download or QSAR
Found 78 Enz. Inhib. hit(s) with all data for entry = 50015203
TargetNociceptin receptor(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O
Show InChI InChI=1S/C79H129N27O22/c1-41(2)33-54(72(122)95-44(5)66(116)103-56(36-59(84)110)73(123)102-53(77(127)128)27-28-58(83)109)104-70(120)49(23-13-15-29-80)100-69(119)52(26-18-32-90-79(87)88)99-65(115)43(4)96-75(125)57(40-107)105-71(121)50(24-14-16-30-81)101-68(118)51(25-17-31-89-78(85)86)98-64(114)42(3)94-61(112)39-93-76(126)63(45(6)108)106-74(124)55(35-47-21-11-8-12-22-47)97-62(113)38-91-60(111)37-92-67(117)48(82)34-46-19-9-7-10-20-46/h7-12,19-22,41-45,48-57,63,107-108H,13-18,23-40,80-82H2,1-6H3,(H2,83,109)(H2,84,110)(H,91,111)(H,92,117)(H,93,126)(H,94,112)(H,95,122)(H,96,125)(H,97,113)(H,98,114)(H,99,115)(H,100,119)(H,101,118)(H,102,123)(H,103,116)(H,104,120)(H,105,121)(H,106,124)(H,127,128)(H4,85,86,89)(H4,87,88,90)/t42-,43-,44-,45+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-/m0/s1
Affinity DataKi:  0.00130nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50029188(CHEMBL2165920)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H72N14O10/c1-24(2)21-31(57-40(65)30(23-35(47)61)56-42(67)33-15-10-20-59(33)44(69)36(48)25(3)4)43(68)58-19-9-14-32(58)41(66)54-28(16-17-34(46)60)39(64)53-27(13-8-18-52-45(50)51)38(63)55-29(37(49)62)22-26-11-6-5-7-12-26/h5-7,11-12,24-25,27-33,36H,8-10,13-23,48H2,1-4H3,(H2,46,60)(H2,47,61)(H2,49,62)(H,53,64)(H,54,66)(H,55,63)(H,56,67)(H,57,65)(H4,50,51,52)/t27-,28-,29-,30-,31-,32-,33-,36-/m0/s1
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C54H76N14O10/c1-32(2)28-41(66-47(72)36(55)29-33-14-6-3-7-15-33)50(75)67-42(31-35-18-10-5-11-19-35)51(76)64-39(23-25-45(57)70)53(78)68-27-13-21-43(68)52(77)63-38(22-24-44(56)69)49(74)62-37(20-12-26-61-54(59)60)48(73)65-40(46(58)71)30-34-16-8-4-9-17-34/h3-11,14-19,32,36-43H,12-13,20-31,55H2,1-2H3,(H2,56,69)(H2,57,70)(H2,58,71)(H,62,74)(H,63,77)(H,64,76)(H,65,73)(H,66,72)(H,67,75)(H4,59,60,61)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
Affinity DataKi:  0.0200nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C54H76N14O10/c1-32(2)28-41(66-47(72)36(55)29-33-14-6-3-7-15-33)50(75)67-42(31-35-18-10-5-11-19-35)51(76)64-39(23-25-45(57)70)53(78)68-27-13-21-43(68)52(77)63-38(22-24-44(56)69)49(74)62-37(20-12-26-61-54(59)60)48(73)65-40(46(58)71)30-34-16-8-4-9-17-34/h3-11,14-19,32,36-43H,12-13,20-31,55H2,1-2H3,(H2,56,69)(H2,57,70)(H2,58,71)(H,62,74)(H,63,77)(H,64,76)(H,65,73)(H,66,72)(H,67,75)(H4,59,60,61)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
Affinity DataKi:  0.0600nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetKiSS-1 receptor(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50045513(Kisspeptin-10)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Affinity DataKi:  0.0620nMAssay Description:Displacement of [125I]-Kp-10 from human Kiss1 receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583768(CHEMBL5093771)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1Br)C(N)=O
Show InChI InChI=1S/C30H33BrN6O3/c31-24-15-8-7-14-22(24)18-26(28(32)39)37-29(40)25(16-9-17-35-30(33)34)36-27(38)19-23(20-10-3-1-4-11-20)21-12-5-2-6-13-21/h1-8,10-15,19,25-26H,9,16-18H2,(H2,32,39)(H,36,38)(H,37,40)(H4,33,34,35)/t25-,26+/m1/s1
Affinity DataKi:  0.730nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50029188(CHEMBL2165920)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H72N14O10/c1-24(2)21-31(57-40(65)30(23-35(47)61)56-42(67)33-15-10-20-59(33)44(69)36(48)25(3)4)43(68)58-19-9-14-32(58)41(66)54-28(16-17-34(46)60)39(64)53-27(13-8-18-52-45(50)51)38(63)55-29(37(49)62)22-26-11-6-5-7-12-26/h5-7,11-12,24-25,27-33,36H,8-10,13-23,48H2,1-4H3,(H2,46,60)(H2,47,61)(H2,49,62)(H,53,64)(H,54,66)(H,55,63)(H,56,67)(H,57,65)(H4,50,51,52)/t27-,28-,29-,30-,31-,32-,33-,36-/m0/s1
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 2(Mus musculus)
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C54H76N14O10/c1-32(2)28-41(66-47(72)36(55)29-33-14-6-3-7-15-33)50(75)67-42(31-35-18-10-5-11-19-35)51(76)64-39(23-25-45(57)70)53(78)68-27-13-21-43(68)52(77)63-38(22-24-44(56)69)49(74)62-37(20-12-26-61-54(59)60)48(73)65-40(46(58)71)30-34-16-8-4-9-17-34/h3-11,14-19,32,36-43H,12-13,20-31,55H2,1-2H3,(H2,56,69)(H2,57,70)(H2,58,71)(H,62,74)(H,63,77)(H,64,76)(H,65,73)(H,66,72)(H,67,75)(H4,59,60,61)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50347819(CHEMBL1802414 | P550)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)N)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C126H195N37O37/c1-65(2)49-83(155-122(199)94-35-24-48-163(94)98(174)59-142-107(184)89(60-164)157-103(180)68(7)128)106(183)141-58-97(173)162-101(70(9)169)123(200)156-84(50-66(3)4)113(190)143-69(8)104(181)145-80(40-42-99(175)176)111(188)150-81(41-43-100(177)178)112(189)152-85(51-67(5)6)114(191)158-93(64-168)121(198)161-92(63-167)120(197)154-88(55-74-36-38-75(170)39-37-74)117(194)160-90(61-165)118(195)149-78(33-22-46-137-125(132)133)109(186)147-77(32-21-45-136-124(130)131)108(185)146-76(31-19-20-44-127)105(182)140-56-95(171)139-57-96(172)144-86(53-72-27-15-11-16-28-72)115(192)159-91(62-166)119(196)153-87(54-73-29-17-12-18-30-73)116(193)148-79(34-23-47-138-126(134)135)110(187)151-82(102(129)179)52-71-25-13-10-14-26-71/h10-18,25-30,36-39,65-70,76-94,101,164-170H,19-24,31-35,40-64,127-128H2,1-9H3,(H2,129,179)(H,139,171)(H,140,182)(H,141,183)(H,142,184)(H,143,190)(H,144,172)(H,145,181)(H,146,185)(H,147,186)(H,148,193)(H,149,195)(H,150,188)(H,151,187)(H,152,189)(H,153,196)(H,154,197)(H,155,199)(H,156,200)(H,157,180)(H,158,191)(H,159,192)(H,160,194)(H,161,198)(H,162,173)(H,175,176)(H,177,178)(H4,130,131,136)(H4,132,133,137)(H4,134,135,138)/t68-,69-,70+,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,101-/m0/s1
Affinity DataKi:  2nMAssay Description:Displacement of [125I]-43RFa from human QRFP receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetProlactin-releasing peptide(Homo sapiens)
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583783(CHEMBL5082678)
Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-PrRP-20 from human PrRP receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583768(CHEMBL5093771)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1Br)C(N)=O
Show InChI InChI=1S/C30H33BrN6O3/c31-24-15-8-7-14-22(24)18-26(28(32)39)37-29(40)25(16-9-17-35-30(33)34)36-27(38)19-23(20-10-3-1-4-11-20)21-12-5-2-6-13-21/h1-8,10-15,19,25-26H,9,16-18H2,(H2,32,39)(H,36,38)(H,37,40)(H4,33,34,35)/t25-,26+/m1/s1
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583765(CHEMBL5090293)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C30H34N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h1-9,11-16,20,25-26H,10,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26+/m1/s1
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583777(CHEMBL5085324)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C27H36N6O3/c1-18(2)16-23(25(28)35)33-26(36)22(14-9-15-31-27(29)30)32-24(34)17-21(19-10-5-3-6-11-19)20-12-7-4-8-13-20/h3-8,10-13,17-18,22-23H,9,14-16H2,1-2H3,(H2,28,35)(H,32,34)(H,33,36)(H4,29,30,31)/t22-,23+/m1/s1
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583770(CHEMBL5071745)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583767(CHEMBL5075638)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCc1ccccc1)C(N)=O
Show InChI InChI=1S/C31H36N6O3/c32-29(39)26(19-18-22-11-4-1-5-12-22)37-30(40)27(17-10-20-35-31(33)34)36-28(38)21-25(23-13-6-2-7-14-23)24-15-8-3-9-16-24/h1-9,11-16,21,26-27H,10,17-20H2,(H2,32,39)(H,36,38)(H,37,40)(H4,33,34,35)/t26-,27+/m0/s1
Affinity DataKi:  6.60nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50402442(CHEMBL2208303)
Show SMILES NC(N)=NCCC[C@@H](NC(=O)C=Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C24H30N6O3/c25-22(32)20(16-18-10-5-2-6-11-18)30-23(33)19(12-7-15-28-24(26)27)29-21(31)14-13-17-8-3-1-4-9-17/h1-6,8-11,13-14,19-20H,7,12,15-16H2,(H2,25,32)(H,29,31)(H,30,33)(H4,26,27,28)/t19-,20+/m1/s1
Affinity DataKi:  7.20nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583766(CHEMBL5074999)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C30H34N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h1-9,11-16,20,25-26H,10,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26-/m1/s1
Affinity DataKi:  7.20nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583769(CHEMBL5082175)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1Br)C(N)=O
Show InChI InChI=1S/C30H33BrN6O3/c31-24-15-8-7-14-22(24)18-26(28(32)39)37-29(40)25(16-9-17-35-30(33)34)36-27(38)19-23(20-10-3-1-4-11-20)21-12-5-2-6-13-21/h1-8,10-15,19,25-26H,9,16-18H2,(H2,32,39)(H,36,38)(H,37,40)(H4,33,34,35)/t25-,26-/m1/s1
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583773(CHEMBL5091013)
Show SMILES NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H28N6O3/c24-20(30)15-28-22(32)19(12-7-13-27-23(25)26)29-21(31)14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,14,19H,7,12-13,15H2,(H2,24,30)(H,28,32)(H,29,31)(H4,25,26,27)/t19-/m1/s1
Affinity DataKi:  11nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Show SMILES NC(N)=NCCC[C@H](NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C26H38N6O3/c27-22(33)21(12-16-5-2-1-3-6-16)31-23(34)20(7-4-8-30-25(28)29)32-24(35)26-13-17-9-18(14-26)11-19(10-17)15-26/h1-3,5-6,17-21H,4,7-15H2,(H2,27,33)(H,31,34)(H,32,35)(H4,28,29,30)/t17?,18?,19?,20-,21-,26?/m0/s1
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583775(CHEMBL5088703)
Show SMILES C[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C24H30N6O3/c1-16(22(25)32)29-23(33)20(13-8-14-28-24(26)27)30-21(31)15-19(17-9-4-2-5-10-17)18-11-6-3-7-12-18/h2-7,9-12,15-16,20H,8,13-14H2,1H3,(H2,25,32)(H,29,33)(H,30,31)(H4,26,27,28)/t16-,20-/m1/s1
Affinity DataKi:  16nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Show SMILES NC(N)=NCCC[C@H](NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C26H38N6O3/c27-22(33)21(12-16-5-2-1-3-6-16)31-23(34)20(7-4-8-30-25(28)29)32-24(35)26-13-17-9-18(14-26)11-19(10-17)15-26/h1-3,5-6,17-21H,4,7-15H2,(H2,27,33)(H,31,34)(H,32,35)(H4,28,29,30)/t17?,18?,19?,20-,21-,26?/m0/s1
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583771(CHEMBL5084208)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Affinity DataKi:  21nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583772(CHEMBL5087609)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
Show InChI InChI=1S/C30H34N6O4/c31-28(39)26(18-20-13-15-23(37)16-14-20)36-29(40)25(12-7-17-34-30(32)33)35-27(38)19-24(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-6,8-11,13-16,19,25-26,37H,7,12,17-18H2,(H2,31,39)(H,35,38)(H,36,40)(H4,32,33,34)/t25-,26+/m1/s1
Affinity DataKi:  32nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583779(CHEMBL5093184)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C27H36N6O3/c1-3-18(2)24(25(28)35)33-26(36)22(15-10-16-31-27(29)30)32-23(34)17-21(19-11-6-4-7-12-19)20-13-8-5-9-14-20/h4-9,11-14,17-18,22,24H,3,10,15-16H2,1-2H3,(H2,28,35)(H,32,34)(H,33,36)(H4,29,30,31)/t18-,22+,24-/m0/s1
Affinity DataKi:  39nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-Diprenorphine from human DOP receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583781(CHEMBL5082273)
Show SMILES NC(=O)CC[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C26H33N7O4/c27-22(34)14-13-20(24(28)36)33-25(37)21(12-7-15-31-26(29)30)32-23(35)16-19(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-6,8-11,16,20-21H,7,12-15H2,(H2,27,34)(H2,28,36)(H,32,35)(H,33,37)(H4,29,30,31)/t20-,21+/m0/s1
Affinity DataKi:  58nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(N)=O)c1ccccc1
Show InChI InChI=1S/C28H32N6O3/c29-25(35)24(21-15-8-3-9-16-21)34-26(36)22(17-10-18-32-28(30)31)33-27(37)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-24H,10,17-18H2,(H2,29,35)(H,33,37)(H,34,36)(H4,30,31,32)/t22-,24-/m1/s1
Affinity DataKi:  58nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583776(CHEMBL5088429)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C26H34N6O3/c1-17(2)23(24(27)34)32-25(35)21(14-9-15-30-26(28)29)31-22(33)16-20(18-10-5-3-6-11-18)19-12-7-4-8-13-19/h3-8,10-13,16-17,21,23H,9,14-15H2,1-2H3,(H2,27,34)(H,31,33)(H,32,35)(H4,28,29,30)/t21-,23+/m1/s1
Affinity DataKi:  68nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50402441(CHEMBL2208304)
Show SMILES NC(N)=NCCC[C@@H](NC(=O)C=Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C24H30N6O3/c25-22(32)20(16-18-10-5-2-6-11-18)30-23(33)19(12-7-15-28-24(26)27)29-21(31)14-13-17-8-3-1-4-9-17/h1-6,8-11,13-14,19-20H,7,12,15-16H2,(H2,25,32)(H,29,31)(H,30,33)(H4,26,27,28)/t19-,20-/m1/s1
Affinity DataKi:  73nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583774(CHEMBL5082270)
Show SMILES C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C24H30N6O3/c1-16(22(25)32)29-23(33)20(13-8-14-28-24(26)27)30-21(31)15-19(17-9-4-2-5-10-17)18-11-6-3-7-12-18/h2-7,9-12,15-16,20H,8,13-14H2,1H3,(H2,25,32)(H,29,33)(H,30,31)(H4,26,27,28)/t16-,20+/m0/s1
Affinity DataKi:  79nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583769(CHEMBL5082175)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1Br)C(N)=O
Show InChI InChI=1S/C30H33BrN6O3/c31-24-15-8-7-14-22(24)18-26(28(32)39)37-29(40)25(16-9-17-35-30(33)34)36-27(38)19-23(20-10-3-1-4-11-20)21-12-5-2-6-13-21/h1-8,10-15,19,25-26H,9,16-18H2,(H2,32,39)(H,36,38)(H,37,40)(H4,33,34,35)/t25-,26-/m1/s1
Affinity DataKi:  84nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583782(CHEMBL5091693)
Show SMILES NC(=O)C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C25H31N7O4/c26-21(33)15-20(23(27)35)32-24(36)19(12-7-13-30-25(28)29)31-22(34)14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,14,19-20H,7,12-13,15H2,(H2,26,33)(H2,27,35)(H,31,34)(H,32,36)(H4,28,29,30)/t19-,20+/m1/s1
Affinity DataKi:  132nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583771(CHEMBL5084208)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Affinity DataKi:  153nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50402442(CHEMBL2208303)
Show SMILES NC(N)=NCCC[C@@H](NC(=O)C=Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C24H30N6O3/c25-22(32)20(16-18-10-5-2-6-11-18)30-23(33)19(12-7-15-28-24(26)27)29-21(31)14-13-17-8-3-1-4-9-17/h1-6,8-11,13-14,19-20H,7,12,15-16H2,(H2,25,32)(H,29,31)(H,30,33)(H4,26,27,28)/t19-,20+/m1/s1
Affinity DataKi:  175nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583765(CHEMBL5090293)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C30H34N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h1-9,11-16,20,25-26H,10,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26+/m1/s1
Affinity DataKi:  205nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(N)=O)c1ccccc1
Show InChI InChI=1S/C28H32N6O3/c29-25(35)24(21-15-8-3-9-16-21)34-26(36)22(17-10-18-32-28(30)31)33-27(37)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-24H,10,17-18H2,(H2,29,35)(H,33,37)(H,34,36)(H4,30,31,32)/t22-,24-/m1/s1
Affinity DataKi:  255nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583770(CHEMBL5071745)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O
Affinity DataKi:  267nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583772(CHEMBL5087609)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
Show InChI InChI=1S/C30H34N6O4/c31-28(39)26(18-20-13-15-23(37)16-14-20)36-29(40)25(12-7-17-34-30(32)33)35-27(38)19-24(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-6,8-11,13-16,19,25-26,37H,7,12,17-18H2,(H2,31,39)(H,35,38)(H,36,40)(H4,32,33,34)/t25-,26+/m1/s1
Affinity DataKi:  512nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583778(CHEMBL5076959)
Show SMILES CC(C)C[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C27H36N6O3/c1-18(2)16-23(25(28)35)33-26(36)22(14-9-15-31-27(29)30)32-24(34)17-21(19-10-5-3-6-11-19)20-12-7-4-8-13-20/h3-8,10-13,17-18,22-23H,9,14-16H2,1-2H3,(H2,28,35)(H,32,34)(H,33,36)(H4,29,30,31)/t22-,23-/m1/s1
Affinity DataKi:  523nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583767(CHEMBL5075638)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCc1ccccc1)C(N)=O
Show InChI InChI=1S/C31H36N6O3/c32-29(39)26(19-18-22-11-4-1-5-12-22)37-30(40)27(17-10-20-35-31(33)34)36-28(38)21-25(23-13-6-2-7-14-23)24-15-8-3-9-16-24/h1-9,11-16,21,26-27H,10,17-20H2,(H2,32,39)(H,36,38)(H,37,40)(H4,33,34,35)/t26-,27+/m0/s1
Affinity DataKi:  557nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583775(CHEMBL5088703)
Show SMILES C[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C24H30N6O3/c1-16(22(25)32)29-23(33)20(13-8-14-28-24(26)27)30-21(31)15-19(17-9-4-2-5-10-17)18-11-6-3-7-12-18/h2-7,9-12,15-16,20H,8,13-14H2,1H3,(H2,25,32)(H,29,33)(H,30,31)(H4,26,27,28)/t16-,20-/m1/s1
Affinity DataKi:  557nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583780(CHEMBL5085023)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(N)=O
Show InChI InChI=1S/C30H40N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h2-3,6-9,13-16,20-21,25-26H,1,4-5,10-12,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26+/m1/s1
Affinity DataKi:  591nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583766(CHEMBL5074999)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C30H34N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h1-9,11-16,20,25-26H,10,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26-/m1/s1
Affinity DataKi:  727nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Mus musculus)
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50565180(CHEMBL4776204)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(N)=O)c1ccccc1
Show InChI InChI=1S/C28H32N6O3/c29-25(35)24(21-15-8-3-9-16-21)34-26(36)22(17-10-18-32-28(30)31)33-27(37)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-24H,10,17-18H2,(H2,29,35)(H,33,37)(H,34,36)(H4,30,31,32)/t22-,24-/m1/s1
Affinity DataKi:  824nMAssay Description:Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNociceptin receptor(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583766(CHEMBL5074999)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C30H34N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h1-9,11-16,20,25-26H,10,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26-/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583780(CHEMBL5085023)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(N)=O
Show InChI InChI=1S/C30H40N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h2-3,6-9,13-16,20-21,25-26H,1,4-5,10-12,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26+/m1/s1
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Mus musculus)
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583766(CHEMBL5074999)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)C=C(c1ccccc1)c1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C30H34N6O3/c31-28(38)26(19-21-11-4-1-5-12-21)36-29(39)25(17-10-18-34-30(32)33)35-27(37)20-24(22-13-6-2-7-14-22)23-15-8-3-9-16-23/h1-9,11-16,20,25-26H,10,17-19H2,(H2,31,38)(H,35,37)(H,36,39)(H4,32,33,34)/t25-,26-/m1/s1
Affinity DataKi:  1.45E+3nMAssay Description:Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583779(CHEMBL5093184)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1)C(N)=O
Show InChI InChI=1S/C27H36N6O3/c1-3-18(2)24(25(28)35)33-26(36)22(15-10-16-31-27(29)30)32-23(34)17-21(19-11-6-4-7-12-19)20-13-8-5-9-14-20/h4-9,11-14,17-18,22,24H,3,10,15-16H2,1-2H3,(H2,28,35)(H,32,34)(H,33,36)(H4,29,30,31)/t18-,22+,24-/m0/s1
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50583773(CHEMBL5091013)
Show SMILES NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC(=O)C=C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H28N6O3/c24-20(30)15-28-22(32)19(12-7-13-27-23(25)26)29-21(31)14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,14,19H,7,12-13,15H2,(H2,24,30)(H,28,32)(H,29,31)(H4,25,26,27)/t19-/m1/s1
Affinity DataKi:  1.69E+3nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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