Compile Data Set for Download or QSAR
Found 39 Enz. Inhib. hit(s) with all data for entry = 50029990
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290032(2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C19H17ClN2S/c20-16-7-5-14(6-8-16)13-22-11-9-15(10-12-22)19-21-17-3-1-2-4-18(17)23-19/h1-9H,10-13H2
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290030(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzo...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2s1)c1ccccc1
Show InChI InChI=1S/C19H18N2S/c1-2-6-15(7-3-1)14-21-12-10-16(11-13-21)19-20-17-8-4-5-9-18(17)22-19/h1-10H,11-14H2
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290034(2-[1-(3-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1cccc(CN2CCC(=CC2)c2nc3ccccc3s2)c1
Show InChI InChI=1S/C19H17ClN2S/c20-16-5-3-4-14(12-16)13-22-10-8-15(9-11-22)19-21-17-6-1-2-7-18(17)23-19/h1-8,12H,9-11,13H2
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290025(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3cc(Cl)ccc3o2)cc1
Show InChI InChI=1S/C19H16Cl2N2O/c20-15-3-1-13(2-4-15)12-23-9-7-14(8-10-23)19-22-17-11-16(21)5-6-18(17)24-19/h1-7,11H,8-10,12H2
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290029(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccc(Cl)cc3[nH]2)cc1
Show InChI InChI=1S/C19H17Cl2N3/c20-15-3-1-13(2-4-15)12-24-9-7-14(8-10-24)19-22-17-6-5-16(21)11-18(17)23-19/h1-7,11H,8-10,12H2,(H,22,23)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290036(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2oc(nc2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H17ClN2O/c20-16-6-7-18-17(12-16)21-19(23-18)15-8-10-22(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290031(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3cc(Cl)ccc3s2)cc1
Show InChI InChI=1S/C19H16Cl2N2S/c20-15-3-1-13(2-4-15)12-23-9-7-14(8-10-23)19-22-17-11-16(21)5-6-18(17)24-19/h1-7,11H,8-10,12H2
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290028(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2nc([nH]c2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H18ClN3/c20-16-6-7-17-18(12-16)22-19(21-17)15-8-10-23(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2,(H,21,22)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290035(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2sc(nc2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H17ClN2S/c20-16-6-7-18-17(12-16)21-19(23-18)15-8-10-22(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2
Affinity DataKi:  44nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290037(2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccccc3[nH]2)cc1
Show InChI InChI=1S/C19H18ClN3/c20-16-7-5-14(6-8-16)13-23-11-9-15(10-12-23)19-21-17-3-1-2-4-18(17)22-19/h1-9H,10-13H2,(H,21,22)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290033(2-[1-(2-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccccc1CN1CCC(=CC1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H17ClN2S/c20-16-6-2-1-5-15(16)13-22-11-9-14(10-12-22)19-21-17-7-3-4-8-18(17)23-19/h1-9H,10-13H2
Affinity DataKi:  87nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290026(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-be...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2[nH]1)c1ccccc1
Show InChI InChI=1S/C19H19N3/c1-2-6-15(7-3-1)14-22-12-10-16(11-13-22)19-20-17-8-4-5-9-18(17)21-19/h1-10H,11-14H2,(H,20,21)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290027(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzo...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2o1)c1ccccc1
Show InChI InChI=1S/C19H18N2O/c1-2-6-15(7-3-1)14-21-12-10-16(11-13-21)19-20-17-8-4-5-9-18(17)22-19/h1-10H,11-14H2
Affinity DataKi:  97nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290027(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzo...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2o1)c1ccccc1
Show InChI InChI=1S/C19H18N2O/c1-2-6-15(7-3-1)14-21-12-10-16(11-13-21)19-20-17-8-4-5-9-18(17)22-19/h1-10H,11-14H2
Affinity DataKi:  240nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290029(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccc(Cl)cc3[nH]2)cc1
Show InChI InChI=1S/C19H17Cl2N3/c20-15-3-1-13(2-4-15)12-24-9-7-14(8-10-24)19-22-17-6-5-16(21)11-18(17)23-19/h1-7,11H,8-10,12H2,(H,22,23)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290034(2-[1-(3-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1cccc(CN2CCC(=CC2)c2nc3ccccc3s2)c1
Show InChI InChI=1S/C19H17ClN2S/c20-16-5-3-4-14(12-16)13-22-10-8-15(9-11-22)19-21-17-6-1-2-7-18(17)23-19/h1-8,12H,9-11,13H2
Affinity DataKi:  340nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290030(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzo...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2s1)c1ccccc1
Show InChI InChI=1S/C19H18N2S/c1-2-6-15(7-3-1)14-21-12-10-16(11-13-21)19-20-17-8-4-5-9-18(17)22-19/h1-10H,11-14H2
Affinity DataKi:  560nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290028(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2nc([nH]c2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H18ClN3/c20-16-6-7-17-18(12-16)22-19(21-17)15-8-10-23(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2,(H,21,22)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290030(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzo...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2s1)c1ccccc1
Show InChI InChI=1S/C19H18N2S/c1-2-6-15(7-3-1)14-21-12-10-16(11-13-21)19-20-17-8-4-5-9-18(17)22-19/h1-10H,11-14H2
Affinity DataKi:  600nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290034(2-[1-(3-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1cccc(CN2CCC(=CC2)c2nc3ccccc3s2)c1
Show InChI InChI=1S/C19H17ClN2S/c20-16-5-3-4-14(12-16)13-22-10-8-15(9-11-22)19-21-17-6-1-2-7-18(17)23-19/h1-8,12H,9-11,13H2
Affinity DataKi:  630nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290031(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3cc(Cl)ccc3s2)cc1
Show InChI InChI=1S/C19H16Cl2N2S/c20-15-3-1-13(2-4-15)12-23-9-7-14(8-10-23)19-22-17-11-16(21)5-6-18(17)24-19/h1-7,11H,8-10,12H2
Affinity DataKi:  660nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290037(2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccccc3[nH]2)cc1
Show InChI InChI=1S/C19H18ClN3/c20-16-7-5-14(6-8-16)13-23-11-9-15(10-12-23)19-21-17-3-1-2-4-18(17)22-19/h1-9H,10-13H2,(H,21,22)
Affinity DataKi:  670nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290029(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccc(Cl)cc3[nH]2)cc1
Show InChI InChI=1S/C19H17Cl2N3/c20-15-3-1-13(2-4-15)12-24-9-7-14(8-10-24)19-22-17-6-5-16(21)11-18(17)23-19/h1-7,11H,8-10,12H2,(H,22,23)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290026(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-be...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2[nH]1)c1ccccc1
Show InChI InChI=1S/C19H19N3/c1-2-6-15(7-3-1)14-22-12-10-16(11-13-22)19-20-17-8-4-5-9-18(17)21-19/h1-10H,11-14H2,(H,20,21)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290033(2-[1-(2-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccccc1CN1CCC(=CC1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H17ClN2S/c20-16-6-2-1-5-15(16)13-22-11-9-14(10-12-22)19-21-17-7-3-4-8-18(17)23-19/h1-9H,10-13H2
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290035(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2sc(nc2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H17ClN2S/c20-16-6-7-18-17(12-16)21-19(23-18)15-8-10-22(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2
Affinity DataKi: >1.60E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290036(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2oc(nc2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H17ClN2O/c20-16-6-7-18-17(12-16)21-19(23-18)15-8-10-22(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290032(2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C19H17ClN2S/c20-16-7-5-14(6-8-16)13-22-11-9-15(10-12-22)19-21-17-3-1-2-4-18(17)23-19/h1-9H,10-13H2
Affinity DataKi: >1.60E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290037(2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccccc3[nH]2)cc1
Show InChI InChI=1S/C19H18ClN3/c20-16-7-5-14(6-8-16)13-23-11-9-15(10-12-23)19-21-17-3-1-2-4-18(17)22-19/h1-9H,10-13H2,(H,21,22)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290025(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3cc(Cl)ccc3o2)cc1
Show InChI InChI=1S/C19H16Cl2N2O/c20-15-3-1-13(2-4-15)12-23-9-7-14(8-10-23)19-22-17-11-16(21)5-6-18(17)24-19/h1-7,11H,8-10,12H2
Affinity DataKi: >1.70E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290035(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2sc(nc2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H17ClN2S/c20-16-6-7-18-17(12-16)21-19(23-18)15-8-10-22(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290036(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2oc(nc2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H17ClN2O/c20-16-6-7-18-17(12-16)21-19(23-18)15-8-10-22(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2
Affinity DataKi: >1.80E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290031(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3cc(Cl)ccc3s2)cc1
Show InChI InChI=1S/C19H16Cl2N2S/c20-15-3-1-13(2-4-15)12-23-9-7-14(8-10-23)19-22-17-11-16(21)5-6-18(17)24-19/h1-7,11H,8-10,12H2
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290033(2-[1-(2-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccccc1CN1CCC(=CC1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H17ClN2S/c20-16-6-2-1-5-15(16)13-22-11-9-14(10-12-22)19-21-17-7-3-4-8-18(17)23-19/h1-9H,10-13H2
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine D2 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290028(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chl...)
Show SMILES Clc1ccc2nc([nH]c2c1)C1=CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H18ClN3/c20-16-6-7-17-18(12-16)22-19(21-17)15-8-10-23(11-9-15)13-14-4-2-1-3-5-14/h1-8,12H,9-11,13H2,(H,21,22)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290032(2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C19H17ClN2S/c20-16-7-5-14(6-8-16)13-22-11-9-15(10-12-22)19-21-17-3-1-2-4-18(17)23-19/h1-9H,10-13H2
Affinity DataKi: >4.40E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290026(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-be...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2[nH]1)c1ccccc1
Show InChI InChI=1S/C19H19N3/c1-2-6-15(7-3-1)14-22-12-10-16(11-13-22)19-20-17-8-4-5-9-18(17)21-19/h1-10H,11-14H2,(H,20,21)
Affinity DataKi:  4.40E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290025(5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro...)
Show SMILES Clc1ccc(CN2CCC(=CC2)c2nc3cc(Cl)ccc3o2)cc1
Show InChI InChI=1S/C19H16Cl2N2O/c20-15-3-1-13(2-4-15)12-23-9-7-14(8-10-23)19-22-17-11-16(21)5-6-18(17)24-19/h1-7,11H,8-10,12H2
Affinity DataKi: >4.50E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290027(2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzo...)
Show SMILES C(N1CCC(=CC1)c1nc2ccccc2o1)c1ccccc1
Show InChI InChI=1S/C19H18N2O/c1-2-6-15(7-3-1)14-21-12-10-16(11-13-21)19-20-17-8-4-5-9-18(17)22-19/h1-10H,11-14H2
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H]-spiperone from human dopamine receptor subtype hD3 expressed in CHO cellsMore data for this Ligand-Target Pair