Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with all data for entry = 50035291
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
The University of Birmingham

Curated by ChEMBL
LigandPNGBDBM50127646(CHEMBL42577 | Phosphoric acid 4-amino-phenyl ester...)
Show SMILES CCOP(=O)(OCC)Oc1ccc(N)cc1
Show InChI InChI=1S/C10H16NO4P/c1-3-13-16(12,14-4-2)15-10-7-5-9(11)6-8-10/h5-8H,3-4,11H2,1-2H3
Affinity DataIC50: 1.28E+6nMAssay Description:Inhibitory activity against human serum paraoxonase (PON1)More data for this Ligand-Target Pair
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
The University of Birmingham

Curated by ChEMBL
LigandPNGBDBM14675(CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...)
Show SMILES OP(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)
Affinity DataIC50: 3.25E+6nMAssay Description:Inhibitory activity against human serum paraoxonase (PON1)More data for this Ligand-Target Pair
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
The University of Birmingham

Curated by ChEMBL
LigandPNGBDBM50127647(CHEMBL296745 | Phosphoric acid diethyl ester pheny...)
Show SMILES CCOP(=O)(OCC)Oc1ccccc1
Show InChI InChI=1S/C10H15O4P/c1-3-12-15(11,13-4-2)14-10-8-6-5-7-9-10/h5-9H,3-4H2,1-2H3
Affinity DataIC50: 3.27E+6nMAssay Description:Inhibitory activity against human serum paraoxonase (PON1)More data for this Ligand-Target Pair
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
The University of Birmingham

Curated by ChEMBL
LigandPNGBDBM24514(4-nitrophenoxyphosphonic acid | 4-nitrophenyl phos...)
Show SMILES OP(O)(=O)Oc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C6H6NO6P/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12/h1-4H,(H2,10,11,12)
Affinity DataIC50: 1.85E+7nMAssay Description:Inhibitory activity against human serum paraoxonase (PON1)More data for this Ligand-Target Pair