Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for entry = 50035339
TargetP2X purinoceptor 7(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50135425(4-{2-(Isoquinoline-5-sulfonylamino)-3-[4-(isoquino...)
Affinity DataIC50:  1nMAssay Description:Antagonistic activity against P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  51nMAssay Description:Antagonistic activity against P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50414329(CHEMBL336545)
Affinity DataIC50:  158nMAssay Description:Antagonistic activity against P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50421620(CHEMBL337984)
Affinity DataIC50:  398nMAssay Description:Antagonistic activity against P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50414328(CHEMBL339140)
Affinity DataIC50:  501nMAssay Description:Antagonistic activity against P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50414319(CHEMBL128907)
Affinity DataIC50:  3.98E+3nMAssay Description:Antagonistic activity against P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50421619(CHEMBL339145)
Affinity DataIC50:  3.98E+3nMAssay Description:Antagonistic activity against P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed