Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for entry = 50037788
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50192927(CHEMBL373765 | acetic acid (1R,5bS,11aS,13R,13aS,1...)
Affinity DataIC50:  8.10E+3nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50192928((1R,5bR,11aS,13R,13aS,13bS)-1-methoxy-5b,8,8,11a,1...)
Affinity DataIC50:  2.48E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50192925(((1R,5bS,11aS,13R,13aS,13bS)-1,13-dihydroxy-8,8,11...)
Affinity DataIC50:  2.53E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50192926((1R,5bS,11aS,13R,13aS,13bS)-5b-(hydroxymethyl)-8,8...)
Affinity DataIC50:  6.45E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50192924((1R,5bR,11aS,13R,13aS,13bS)-1-hydroxy-5b,8,8,11a,1...)
Affinity DataIC50:  8.11E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed