Found 44 Enz. Inhib. hit(s) with all data for entry = 50039347 
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
AstraZeneca R&D
Curated by ChEMBL
AstraZeneca R&D
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
AstraZeneca R&D
Curated by ChEMBL
AstraZeneca R&D
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of Stat3 phosphorylation in human SET2 cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5A(Homo sapiens (Human))
AstraZeneca R&D
Curated by ChEMBL
AstraZeneca R&D
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Stat5 phosphorylation in human SET2 cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5A(Homo sapiens (Human))
AstraZeneca R&D
Curated by ChEMBL
AstraZeneca R&D
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of Stat5 phosphorylation in human HEL cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
AstraZeneca R&D
Curated by ChEMBL
AstraZeneca R&D
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Stat3 phosphorylation in human HEL cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 346nMAssay Description:Inhibition of JAK2 using Km ATP concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 488nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 815nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of JAK2 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4.59E+3nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.05E+4nMAssay Description:Inhibition of JAK3 using 5 mM of ATPMore data for this Ligand-Target Pair
