Compile Data Set for Download or QSAR
Found 58 Enz. Inhib. hit(s) with all data for entry = 50042540
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427494(CHEMBL2322558)
Show SMILES Cc1c(CCC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2c(C)c3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C29H31NO6/c1-16-19(11-12-24(31)30-23(27(32)33)13-18-9-7-6-8-10-18)28(34)36-26-17(2)25-21(14-20(16)26)22(15-35-25)29(3,4)5/h6-10,14-15,23H,11-13H2,1-5H3,(H,30,31)(H,32,33)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427541(CHEMBL2322276)
Show SMILES Cc1c(CC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12
Show InChI InChI=1S/C27H25NO6/c1-15-18-12-20-17-9-5-6-10-22(17)33-24(20)14-23(18)34-27(32)19(15)13-25(29)28-21(26(30)31)11-16-7-3-2-4-8-16/h2-4,7-8,12,14,21H,5-6,9-11,13H2,1H3,(H,28,29)(H,30,31)
Affinity DataEC50:  8.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427496(CHEMBL2322556)
Show SMILES Cc1c(CC(=O)NCc2ccccc2Cl)c(=O)oc2c(C)c3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C26H26ClNO4/c1-14-17-10-19-20(26(3,4)5)13-31-23(19)15(2)24(17)32-25(30)18(14)11-22(29)28-12-16-8-6-7-9-21(16)27/h6-10,13H,11-12H2,1-5H3,(H,28,29)
Affinity DataEC50:  5.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427497(CHEMBL2322555)
Show SMILES Cc1c(CC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2c(C)c3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C26H25NO6/c1-13-17-10-19-20(26(3,4)5)12-32-22(19)14(2)23(17)33-25(31)18(13)11-21(28)27-16-8-6-15(7-9-16)24(29)30/h6-10,12H,11H2,1-5H3,(H,27,28)(H,29,30)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427498(CHEMBL2322554)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C)c3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C19H20O5/c1-9-11-6-13-14(19(3,4)5)8-23-16(13)10(2)17(11)24-18(22)12(9)7-15(20)21/h6,8H,7H2,1-5H3,(H,20,21)
Affinity DataEC50:  8.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427499(CHEMBL2322553)
Show SMILES Cc1c(CCC(=O)Nc2ccc(CC(O)=O)cc2)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C27H27NO6/c1-15-18(9-10-24(29)28-17-7-5-16(6-8-17)11-25(30)31)26(32)34-23-13-22-20(12-19(15)23)21(14-33-22)27(2,3)4/h5-8,12-14H,9-11H2,1-4H3,(H,28,29)(H,30,31)
Affinity DataEC50:  8.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427500(CHEMBL2322552)
Show SMILES Cc1c(CCC(=O)NCc2ccc(cc2)C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C27H27NO6/c1-15-18(9-10-24(29)28-13-16-5-7-17(8-6-16)25(30)31)26(32)34-23-12-22-20(11-19(15)23)21(14-33-22)27(2,3)4/h5-8,11-12,14H,9-10,13H2,1-4H3,(H,28,29)(H,30,31)
Affinity DataEC50:  6.70E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427501(CHEMBL2322551)
Show SMILES Cc1c(CCC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C26H25NO6/c1-14-17(9-10-23(28)27-16-7-5-15(6-8-16)24(29)30)25(31)33-22-12-21-19(11-18(14)22)20(13-32-21)26(2,3)4/h5-8,11-13H,9-10H2,1-4H3,(H,27,28)(H,29,30)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427502(CHEMBL2321884)
Show SMILES Cc1c(CCC(=O)Nc2cccc(c2)C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C26H25NO6/c1-14-17(8-9-23(28)27-16-7-5-6-15(10-16)24(29)30)25(31)33-22-12-21-19(11-18(14)22)20(13-32-21)26(2,3)4/h5-7,10-13H,8-9H2,1-4H3,(H,27,28)(H,29,30)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427503(CHEMBL2322550)
Show SMILES Cc1c(CCC(=O)Nc2ccccc2C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C26H25NO6/c1-14-15(9-10-23(28)27-20-8-6-5-7-16(20)24(29)30)25(31)33-22-12-21-18(11-17(14)22)19(13-32-21)26(2,3)4/h5-8,11-13H,9-10H2,1-4H3,(H,27,28)(H,29,30)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427504(CHEMBL2322549)
Show SMILES Cc1c(CCC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C28H29NO6/c1-16-18(10-11-25(30)29-22(26(31)32)12-17-8-6-5-7-9-17)27(33)35-24-14-23-20(13-19(16)24)21(15-34-23)28(2,3)4/h5-9,13-15,22H,10-12H2,1-4H3,(H,29,30)(H,31,32)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427505(CHEMBL2322548)
Show SMILES Cc1c(CC(=O)Nc2ccc(CC(O)=O)cc2)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C26H25NO6/c1-14-17-10-19-20(26(2,3)4)13-32-21(19)12-22(17)33-25(31)18(14)11-23(28)27-16-7-5-15(6-8-16)9-24(29)30/h5-8,10,12-13H,9,11H2,1-4H3,(H,27,28)(H,29,30)
Affinity DataEC50:  5.30E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427506(CHEMBL2322547)
Show SMILES Cc1c(CC(=O)NCc2ccc(cc2)C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C26H25NO6/c1-14-17-9-19-20(26(2,3)4)13-32-21(19)11-22(17)33-25(31)18(14)10-23(28)27-12-15-5-7-16(8-6-15)24(29)30/h5-9,11,13H,10,12H2,1-4H3,(H,27,28)(H,29,30)
Affinity DataEC50:  6.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427507(CHEMBL2322546)
Show SMILES Cc1c(CC(=O)Nc2cccc(c2)C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C25H23NO6/c1-13-16-9-18-19(25(2,3)4)12-31-20(18)11-21(16)32-24(30)17(13)10-22(27)26-15-7-5-6-14(8-15)23(28)29/h5-9,11-12H,10H2,1-4H3,(H,26,27)(H,28,29)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427508(CHEMBL2322545)
Show SMILES Cc1c(CC(=O)Nc2ccccc2C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C25H23NO6/c1-13-15-9-17-18(25(2,3)4)12-31-20(17)11-21(15)32-24(30)16(13)10-22(27)26-19-8-6-5-7-14(19)23(28)29/h5-9,11-12H,10H2,1-4H3,(H,26,27)(H,28,29)
Affinity DataEC50:  8.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427509(CHEMBL1829845)
Show SMILES Cc1c(CC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C27H27NO6/c1-15-17-11-19-20(27(2,3)4)14-33-22(19)13-23(17)34-26(32)18(15)12-24(29)28-21(25(30)31)10-16-8-6-5-7-9-16/h5-9,11,13-14,21H,10,12H2,1-4H3,(H,28,29)(H,30,31)
Affinity DataEC50:  6.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427510(CHEMBL2322544)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C
Show InChI InChI=1S/C18H18O5/c1-9-10-5-12-13(18(2,3)4)8-22-14(12)7-15(10)23-17(21)11(9)6-16(19)20/h5,7-8H,6H2,1-4H3,(H,19,20)
Affinity DataEC50:  8.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427511(CHROME AZUROL S | Chrome Azurol)
Show SMILES CC1=C\C(C=C(C([O-])=O)C1=O)=C(\c1cc(C)c(O)c(c1)C([O-])=O)c1c(Cl)ccc(c1Cl)S([O-])(=O)=O
Show InChI InChI=1S/C23H16Cl2O9S/c1-9-5-11(7-13(20(9)26)22(28)29)17(12-6-10(2)21(27)14(8-12)23(30)31)18-15(24)3-4-16(19(18)25)35(32,33)34/h3-8,26H,1-2H3,(H,28,29)(H,30,31)(H,32,33,34)/p-3/b17-12+
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50331546(2-(4,5,6-trihydroxy-3-oxo-3H-xanthen-9-yl)benzenes...)
Show SMILES Oc1ccc2c(-c3ccccc3S(O)(=O)=O)c3ccc(=O)c(O)c3oc2c1O
Show InChI InChI=1S/C19H12O8S/c20-12-7-5-10-15(9-3-1-2-4-14(9)28(24,25)26)11-6-8-13(21)17(23)19(11)27-18(10)16(12)22/h1-8,20,22-23H,(H,24,25,26)
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427512(AURIN | CI-43800 | Corallin | Rosolic acid | Rosol...)
Show SMILES Oc1ccc(cc1)C(=C1C=CC(=O)C=C1)c1ccc(O)cc1
Show InChI InChI=1S/C19H14O3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20-21H
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427513(PYROCATECHOL VIOLET)
Show SMILES Oc1ccc(cc1O)C(=C1CC(=O)C(=O)C=C1)c1ccccc1S(O)(=O)=O
Show InChI InChI=1S/C19H14O7S/c20-14-7-5-11(9-16(14)22)19(12-6-8-15(21)17(23)10-12)13-3-1-2-4-18(13)27(24,25)26/h1-9,20,22H,10H2,(H,24,25,26)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427514(CHEMBL2322249)
Show SMILES Cc1c(CCC(=O)Nc2ccc(cc2)C(N)=O)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C27H26N2O5/c1-14-18(11-12-23(30)29-17-9-7-16(8-10-17)26(28)31)27(32)34-24-15(2)25-21(13-20(14)24)19-5-3-4-6-22(19)33-25/h7-10,13H,3-6,11-12H2,1-2H3,(H2,28,31)(H,29,30)
Affinity DataEC50:  7.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427515(CHEMBL2322248)
Show SMILES Cc1c(CCC(=O)Nc2ccc(NS(C)(=O)=O)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C27H28N2O6S/c1-15-19(12-13-24(30)28-17-8-10-18(11-9-17)29-36(3,32)33)27(31)35-25-16(2)26-22(14-21(15)25)20-6-4-5-7-23(20)34-26/h8-11,14,29H,4-7,12-13H2,1-3H3,(H,28,30)
Affinity DataEC50:  1.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427516(CHEMBL2322266)
Show SMILES CC(=O)Nc1ccc(NC(=O)CCc2c(C)c3cc4c5CCCCc5oc4c(C)c3oc2=O)cc1
Show InChI InChI=1S/C28H28N2O5/c1-15-20(12-13-25(32)30-19-10-8-18(9-11-19)29-17(3)31)28(33)35-26-16(2)27-23(14-22(15)26)21-6-4-5-7-24(21)34-27/h8-11,14H,4-7,12-13H2,1-3H3,(H,29,31)(H,30,32)
Affinity DataEC50:  1.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427517(CHEMBL2322265)
Show SMILES Cc1c(CCC(=O)Nc2ccc(N)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H26N2O4/c1-14-18(11-12-23(29)28-17-9-7-16(27)8-10-17)26(30)32-24-15(2)25-21(13-20(14)24)19-5-3-4-6-22(19)31-25/h7-10,13H,3-6,11-12,27H2,1-2H3,(H,28,29)
Affinity DataEC50:  3.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427518(CHEMBL2322264)
Show SMILES Cc1c(CCC(=O)Nc2cccc(c2)C(F)(F)F)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C27H24F3NO4/c1-14-18(10-11-23(32)31-17-7-5-6-16(12-17)27(28,29)30)26(33)35-24-15(2)25-21(13-20(14)24)19-8-3-4-9-22(19)34-25/h5-7,12-13H,3-4,8-11H2,1-2H3,(H,31,32)
Affinity DataEC50: >1.00E+7nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427519(CHEMBL2322263)
Show SMILES Cc1c(CCC(=O)Nc2ccc(O)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H25NO5/c1-14-18(11-12-23(29)27-16-7-9-17(28)10-8-16)26(30)32-24-15(2)25-21(13-20(14)24)19-5-3-4-6-22(19)31-25/h7-10,13,28H,3-6,11-12H2,1-2H3,(H,27,29)
Affinity DataEC50:  3.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427520(CHEMBL2322262)
Show SMILES Cc1c(CCC(=O)Nc2cccc(O)c2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H25NO5/c1-14-18(10-11-23(29)27-16-6-5-7-17(28)12-16)26(30)32-24-15(2)25-21(13-20(14)24)19-8-3-4-9-22(19)31-25/h5-7,12-13,28H,3-4,8-11H2,1-2H3,(H,27,29)
Affinity DataEC50:  7.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427521(CHEMBL2322261)
Show SMILES Cc1c(CC(=O)Nc2ccc(cc2)C(N)=O)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H24N2O5/c1-13-18-11-20-17-5-3-4-6-21(17)32-24(20)14(2)23(18)33-26(31)19(13)12-22(29)28-16-9-7-15(8-10-16)25(27)30/h7-11H,3-6,12H2,1-2H3,(H2,27,30)(H,28,29)
Affinity DataEC50:  7.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427522(CHEMBL2322260)
Show SMILES Cc1c(CC(=O)Nc2ccc(NS(C)(=O)=O)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H26N2O6S/c1-14-19-12-21-18-6-4-5-7-22(18)33-25(21)15(2)24(19)34-26(30)20(14)13-23(29)27-16-8-10-17(11-9-16)28-35(3,31)32/h8-12,28H,4-7,13H2,1-3H3,(H,27,29)
Affinity DataEC50:  7.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427523(CHEMBL2322259)
Show SMILES CC(=O)Nc1ccc(NC(=O)Cc2c(C)c3cc4c5CCCCc5oc4c(C)c3oc2=O)cc1
Show InChI InChI=1S/C27H26N2O5/c1-14-20-12-22-19-6-4-5-7-23(19)33-26(22)15(2)25(20)34-27(32)21(14)13-24(31)29-18-10-8-17(9-11-18)28-16(3)30/h8-12H,4-7,13H2,1-3H3,(H,28,30)(H,29,31)
Affinity DataEC50:  3.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427524(CHEMBL2322258)
Show SMILES Cc1c(CC(=O)Nc2cccc(c2)C(F)(F)F)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H22F3NO4/c1-13-18-11-20-17-8-3-4-9-21(17)33-24(20)14(2)23(18)34-25(32)19(13)12-22(31)30-16-7-5-6-15(10-16)26(27,28)29/h5-7,10-11H,3-4,8-9,12H2,1-2H3,(H,30,31)
Affinity DataEC50:  3.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427525(CHEMBL2322257)
Show SMILES Cc1c(CC(=O)Nc2ccc(O)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C25H23NO5/c1-13-18-11-20-17-5-3-4-6-21(17)30-24(20)14(2)23(18)31-25(29)19(13)12-22(28)26-15-7-9-16(27)10-8-15/h7-11,27H,3-6,12H2,1-2H3,(H,26,28)
Affinity DataEC50:  7.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427526(CHEMBL2322256)
Show SMILES Cc1c(CC(=O)Nc2cccc(O)c2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C25H23NO5/c1-13-18-11-20-17-8-3-4-9-21(17)30-24(20)14(2)23(18)31-25(29)19(13)12-22(28)26-15-6-5-7-16(27)10-15/h5-7,10-11,27H,3-4,8-9,12H2,1-2H3,(H,26,28)
Affinity DataEC50:  3.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427527(CHEMBL2322255)
Show SMILES Cc1oc2c(C)c3oc(=O)c(CCC(=O)Nc4cccc(c4)C(O)=O)c(C)c3cc2c1C
Show InChI InChI=1S/C25H23NO6/c1-12-15(4)31-22-14(3)23-20(11-19(12)22)13(2)18(25(30)32-23)8-9-21(27)26-17-7-5-6-16(10-17)24(28)29/h5-7,10-11H,8-9H2,1-4H3,(H,26,27)(H,28,29)
Affinity DataEC50:  8.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427528(CHEMBL2322254)
Show SMILES Cc1oc2c(C)c3oc(=O)c(CC(=O)Nc4cccc(c4)C(O)=O)c(C)c3cc2c1C
Show InChI InChI=1S/C24H21NO6/c1-11-14(4)30-21-13(3)22-18(9-17(11)21)12(2)19(24(29)31-22)10-20(26)25-16-7-5-6-15(8-16)23(27)28/h5-9H,10H2,1-4H3,(H,25,26)(H,27,28)
Affinity DataEC50:  6.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427529(CHEMBL2321881)
Show SMILES Cc1oc2cc3oc(=O)c(CCC(=O)Nc4cccc(c4)C(O)=O)c(C)c3cc2c1C
Show InChI InChI=1S/C24H21NO6/c1-12-14(3)30-20-11-21-19(10-18(12)20)13(2)17(24(29)31-21)7-8-22(26)25-16-6-4-5-15(9-16)23(27)28/h4-6,9-11H,7-8H2,1-3H3,(H,25,26)(H,27,28)
Affinity DataEC50:  6.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427530(CHEMBL2322253)
Show SMILES Cc1oc2cc3oc(=O)c(CC(=O)Nc4cccc(c4)C(O)=O)c(C)c3cc2c1C
Show InChI InChI=1S/C23H19NO6/c1-11-13(3)29-19-10-20-17(8-16(11)19)12(2)18(23(28)30-20)9-21(25)24-15-6-4-5-14(7-15)22(26)27/h4-8,10H,9H2,1-3H3,(H,24,25)(H,26,27)
Affinity DataEC50:  7.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427531(CHEMBL2322252)
Show SMILES Cc1c(CCC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C27H25NO6/c1-14-18(11-12-23(29)28-17-9-7-16(8-10-17)26(30)31)27(32)34-24-15(2)25-21(13-20(14)24)19-5-3-4-6-22(19)33-25/h7-10,13H,3-6,11-12H2,1-2H3,(H,28,29)(H,30,31)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427532(CHEMBL2322251)
Show SMILES Cc1c(CCC(=O)Nc2cccc(c2)C(O)=O)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C27H25NO6/c1-14-18(10-11-23(29)28-17-7-5-6-16(12-17)26(30)31)27(32)34-24-15(2)25-21(13-20(14)24)19-8-3-4-9-22(19)33-25/h5-7,12-13H,3-4,8-11H2,1-2H3,(H,28,29)(H,30,31)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427533(CHEMBL2322250)
Show SMILES Cc1c(CC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H23NO6/c1-13-18-11-20-17-5-3-4-6-21(17)32-24(20)14(2)23(18)33-26(31)19(13)12-22(28)27-16-9-7-15(8-10-16)25(29)30/h7-11H,3-6,12H2,1-2H3,(H,27,28)(H,29,30)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427534(CHEMBL2322283)
Show SMILES Cc1c(CC(=O)Nc2cccc(c2)C(O)=O)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H23NO6/c1-13-18-11-20-17-8-3-4-9-21(17)32-24(20)14(2)23(18)33-26(31)19(13)12-22(28)27-16-7-5-6-15(10-16)25(29)30/h5-7,10-11H,3-4,8-9,12H2,1-2H3,(H,27,28)(H,29,30)
Affinity DataEC50:  7.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427535(CHEMBL2322282)
Show SMILES Cc1c(CC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2c(C)c3oc4CCCCc4c3cc12
Show InChI InChI=1S/C28H27NO6/c1-15-19-13-21-18-10-6-7-11-23(18)34-26(21)16(2)25(19)35-28(33)20(15)14-24(30)29-22(27(31)32)12-17-8-4-3-5-9-17/h3-5,8-9,13,22H,6-7,10-12,14H2,1-2H3,(H,29,30)(H,31,32)
Affinity DataEC50:  1.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427536(CHEMBL2322281)
Show SMILES Cc1c(CCC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H23NO6/c1-14-17(10-11-24(28)27-16-8-6-15(7-9-16)25(29)30)26(31)33-22-13-23-20(12-19(14)22)18-4-2-3-5-21(18)32-23/h6-9,12-13H,2-5,10-11H2,1H3,(H,27,28)(H,29,30)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427537(CHEMBL2322280)
Show SMILES Cc1c(CCC(=O)Nc2cccc(c2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12
Show InChI InChI=1S/C26H23NO6/c1-14-17(9-10-24(28)27-16-6-4-5-15(11-16)25(29)30)26(31)33-22-13-23-20(12-19(14)22)18-7-2-3-8-21(18)32-23/h4-6,11-13H,2-3,7-10H2,1H3,(H,27,28)(H,29,30)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427538(CHEMBL2322279)
Show SMILES Cc1c(CCC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12
Show InChI InChI=1S/C28H27NO6/c1-16-18(11-12-26(30)29-22(27(31)32)13-17-7-3-2-4-8-17)28(33)35-24-15-25-21(14-20(16)24)19-9-5-6-10-23(19)34-25/h2-4,7-8,14-15,22H,5-6,9-13H2,1H3,(H,29,30)(H,31,32)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427539(CHEMBL2322278)
Show SMILES Cc1c(CC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12
Show InChI InChI=1S/C25H21NO6/c1-13-17-10-19-16-4-2-3-5-20(16)31-22(19)12-21(17)32-25(30)18(13)11-23(27)26-15-8-6-14(7-9-15)24(28)29/h6-10,12H,2-5,11H2,1H3,(H,26,27)(H,28,29)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427542(CHEMBL2322275)
Show SMILES Cc1oc2c(C)c3oc(=O)c(CCC(=O)Nc4ccc(cc4)C(O)=O)c(C)c3cc2c1C
Show InChI InChI=1S/C25H23NO6/c1-12-15(4)31-22-14(3)23-20(11-19(12)22)13(2)18(25(30)32-23)9-10-21(27)26-17-7-5-16(6-8-17)24(28)29/h5-8,11H,9-10H2,1-4H3,(H,26,27)(H,28,29)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427543(CHEMBL2322274)
Show SMILES Cc1oc2c(C)c3oc(=O)c(CCC(=O)NC(Cc4ccccc4)C(O)=O)c(C)c3cc2c1C
Show InChI InChI=1S/C27H27NO6/c1-14-17(4)33-24-16(3)25-21(13-20(14)24)15(2)19(27(32)34-25)10-11-23(29)28-22(26(30)31)12-18-8-6-5-7-9-18/h5-9,13,22H,10-12H2,1-4H3,(H,28,29)(H,30,31)
Affinity DataEC50:  1.00E+6nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£ degli Studi di Padova

Curated by ChEMBL
LigandPNGBDBM50427544(CHEMBL2322273)
Show SMILES Cc1oc2c(C)c3oc(=O)c(CC(=O)Nc4ccc(cc4)C(O)=O)c(C)c3cc2c1C
Show InChI InChI=1S/C24H21NO6/c1-11-14(4)30-21-13(3)22-18(9-17(11)21)12(2)19(24(29)31-22)10-20(26)25-16-7-5-15(6-8-16)23(27)28/h5-9H,10H2,1-4H3,(H,25,26)(H,27,28)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
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