Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with all data for entry = 50043089
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50159011(4-Benzyl-1-(4-phenyl-butyl)-piperidine | CHEMBL178...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)Cc1ccccc1
Show InChI InChI=1S/C21H27N/c1-3-8-19(9-4-1)12-7-15-22-16-13-21(14-17-22)18-20-10-5-2-6-11-20/h1-6,8-11,21H,7,12-18H2
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435872(CHEMBL2391071)
Show SMILES Ic1cccc(CS(=O)(=O)N2CCC(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C19H22INO2S/c20-19-8-4-7-18(14-19)15-24(22,23)21-11-9-17(10-12-21)13-16-5-2-1-3-6-16/h1-8,14,17H,9-13,15H2
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435871(CHEMBL2391070)
Show SMILES Brc1cccc(CS(=O)(=O)N2CCC(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C19H22BrNO2S/c20-19-8-4-7-18(14-19)15-24(22,23)21-11-9-17(10-12-21)13-16-5-2-1-3-6-16/h1-8,14,17H,9-13,15H2
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435865(CHEMBL2391065)
Show SMILES Ic1cccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C18H21IN2O2S/c19-18-8-4-7-17(13-18)14-20-9-11-21(12-10-20)24(22,23)15-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435861(CHEMBL2391061)
Show SMILES Ic1cccc(CS(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C18H21IN2O2S/c19-18-8-4-7-17(13-18)15-24(22,23)21-11-9-20(10-12-21)14-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C(C)C
Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435873(CHEMBL2391072)
Show SMILES Cc1cccc(CS(=O)(=O)N2CCC(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C20H25NO2S/c1-17-6-5-9-20(14-17)16-24(22,23)21-12-10-19(11-13-21)15-18-7-3-2-4-8-18/h2-9,14,19H,10-13,15-16H2,1H3
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50125096(1,4-Dibenzyl-piperazine | 1,4-Dibenzyl-piperazine,...)
Show SMILES C(N1CCN(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C18H22N2/c1-3-7-17(8-4-1)15-19-11-13-20(14-12-19)16-18-9-5-2-6-10-18/h1-10H,11-16H2
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435869(CHEMBL2391068)
Show SMILES O=S(=O)(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H23NO2S/c21-23(22,16-19-9-5-2-6-10-19)20-13-11-18(12-14-20)15-17-7-3-1-4-8-17/h1-10,18H,11-16H2
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435858(CHEMBL1327876)
Show SMILES O=S(=O)(Cc1ccccc1)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C18H22N2O2S/c21-23(22,16-18-9-5-2-6-10-18)20-13-11-19(12-14-20)15-17-7-3-1-4-8-17/h1-10H,11-16H2
Affinity DataKi:  11nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435867(CHEMBL1479800)
Show SMILES Brc1ccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)cc1
Show InChI InChI=1S/C18H21BrN2O2S/c19-18-8-6-16(7-9-18)14-20-10-12-21(13-11-20)24(22,23)15-17-4-2-1-3-5-17/h1-9H,10-15H2
Affinity DataKi:  13nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435866(CHEMBL2391066)
Show SMILES Cc1cccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C19H24N2O2S/c1-17-6-5-9-19(14-17)15-20-10-12-21(13-11-20)24(22,23)16-18-7-3-2-4-8-18/h2-9,14H,10-13,15-16H2,1H3
Affinity DataKi:  15nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50372598(CHEMBL273041)
Show SMILES C(CN1CCN(Cc2ccccc2)CC1)Cc1ccccc1
Show InChI InChI=1S/C20H26N2/c1-3-8-19(9-4-1)12-7-13-21-14-16-22(17-15-21)18-20-10-5-2-6-11-20/h1-6,8-11H,7,12-18H2
Affinity DataKi:  20nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435874(CHEMBL2391073)
Show SMILES O=S(=O)(N1CCC(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C18H21NO2S/c20-22(21,18-9-5-2-6-10-18)19-13-11-17(12-14-19)15-16-7-3-1-4-8-16/h1-10,17H,11-15H2
Affinity DataKi:  24nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435875(CHEMBL272551)
Show SMILES O=S(=O)(N1CCN(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C17H20N2O2S/c20-22(21,17-9-5-2-6-10-17)19-13-11-18(12-14-19)15-16-7-3-1-4-8-16/h1-10H,11-15H2
Affinity DataKi:  28nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435860(CHEMBL2391060)
Show SMILES Brc1cccc(CS(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C18H21BrN2O2S/c19-18-8-4-7-17(13-18)15-24(22,23)21-11-9-20(10-12-21)14-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2
Affinity DataKi:  30nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435862(CHEMBL2391062)
Show SMILES Cc1cccc(CS(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C19H24N2O2S/c1-17-6-5-9-19(14-17)16-24(22,23)21-12-10-20(11-13-21)15-18-7-3-2-4-8-18/h2-9,14H,10-13,15-16H2,1H3
Affinity DataKi:  36nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435884(CHEMBL2391057)
Show SMILES OC[C@@H]1CN(CCc2ccccc2)CCN1Cc1ccccc1
Show InChI InChI=1S/C20H26N2O/c23-17-20-16-21(12-11-18-7-3-1-4-8-18)13-14-22(20)15-19-9-5-2-6-10-19/h1-10,20,23H,11-17H2/t20-/m0/s1
Affinity DataKi:  38nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C
Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
Affinity DataKi:  38nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435870(CHEMBL2391069)
Show SMILES Clc1cccc(CS(=O)(=O)N2CCC(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C19H22ClNO2S/c20-19-8-4-7-18(14-19)15-24(22,23)21-11-9-17(10-12-21)13-16-5-2-1-3-6-16/h1-8,14,17H,9-13,15H2
Affinity DataKi:  40nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435864(CHEMBL2391064)
Show SMILES Clc1cccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C18H21ClN2O2S/c19-18-8-4-7-17(13-18)14-20-9-11-21(12-10-20)24(22,23)15-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2
Affinity DataKi:  52nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435878(CHEMBL2391076)
Show SMILES O=S(=O)(CCc1ccccc1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H25NO2S/c22-24(23,16-13-18-7-3-1-4-8-18)21-14-11-20(12-15-21)17-19-9-5-2-6-10-19/h1-10,20H,11-17H2
Affinity DataKi:  60nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435859(CHEMBL2391059)
Show SMILES Clc1cccc(CS(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C18H21ClN2O2S/c19-18-8-4-7-17(13-18)15-24(22,23)21-11-9-20(10-12-21)14-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2
Affinity DataKi:  68nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435863(CHEMBL2391063)
Show SMILES Fc1cccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C18H21FN2O2S/c19-18-8-4-7-17(13-18)14-20-9-11-21(12-10-20)24(22,23)15-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2
Affinity DataKi:  69nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435879(CHEMBL2391077)
Show SMILES O=S(=O)(CCc1ccccc1)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H24N2O2S/c22-24(23,16-11-18-7-3-1-4-8-18)21-14-12-20(13-15-21)17-19-9-5-2-6-10-19/h1-10H,11-17H2
Affinity DataKi:  78nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435880(CHEMBL2391078)
Show SMILES O=S(=O)(\C=C\c1ccccc1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H23NO2S/c22-24(23,16-13-18-7-3-1-4-8-18)21-14-11-20(12-15-21)17-19-9-5-2-6-10-19/h1-10,13,16,20H,11-12,14-15,17H2/b16-13+
Affinity DataKi:  138nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435868(CHEMBL2391067)
Show SMILES COc1ccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)cc1
Show InChI InChI=1S/C19H24N2O3S/c1-24-19-9-7-17(8-10-19)15-20-11-13-21(14-12-20)25(22,23)16-18-5-3-2-4-6-18/h2-10H,11-16H2,1H3
Affinity DataKi:  192nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435881(CHEMBL1422857)
Show SMILES O=S(=O)(\C=C\c1ccccc1)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H22N2O2S/c22-24(23,16-11-18-7-3-1-4-8-18)21-14-12-20(13-15-21)17-19-9-5-2-6-10-19/h1-11,16H,12-15,17H2/b16-11+
Affinity DataKi:  201nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435876(CHEMBL2391074)
Show SMILES Clc1ccc(cc1)S(=O)(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C18H20ClNO2S/c19-17-6-8-18(9-7-17)23(21,22)20-12-10-16(11-13-20)14-15-4-2-1-3-5-15/h1-9,16H,10-14H2
Affinity DataKi:  551nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435882(CHEMBL2391079)
Show SMILES Brc1ccc(\C=C\S(=O)(=O)N2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H22BrNO2S/c21-20-8-6-17(7-9-20)12-15-25(23,24)22-13-10-19(11-14-22)16-18-4-2-1-3-5-18/h1-9,12,15,19H,10-11,13-14,16H2/b15-12+
Affinity DataKi:  843nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435877(CHEMBL2391075)
Show SMILES Clc1ccc(cc1)S(=O)(=O)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C17H19ClN2O2S/c18-16-6-8-17(9-7-16)23(21,22)20-12-10-19(11-13-20)14-15-4-2-1-3-5-15/h1-9H,10-14H2
Affinity DataKi:  969nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
NSTRI

Curated by ChEMBL
LigandPNGBDBM50435883(CHEMBL2391080)
Show SMILES Brc1ccc(\C=C\S(=O)(=O)N2CCN(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C19H21BrN2O2S/c20-19-8-6-17(7-9-19)10-15-25(23,24)22-13-11-21(12-14-22)16-18-4-2-1-3-5-18/h1-10,15H,11-14,16H2/b15-10+
Affinity DataKi:  1.08E+3nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair