Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with all data for entry = 50048463
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50158841(4-Hydroxy-4H,6H-furo[3,2-c]pyran-2-one | 4-hydroxy...)
Show SMILES OC1OCC=C2OC(=O)C=C12
Show InChI InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
Affinity DataIC50: 3.80nMAssay Description:In vitro antiviral activity against hepatitis C virus (HCV) NS3 protease using scintillation proximity assayMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50158797(Acetic acid 2-oxo-2,6-dihydro-4H-furo[3,2-c]pyran-...)
Show SMILES CC(=O)OC1OCC=C2OC(=O)C=C12
Show InChI InChI=1S/C9H8O5/c1-5(10)13-9-6-4-8(11)14-7(6)2-3-12-9/h2,4,9H,3H2,1H3
Affinity DataIC50: 7.20nMAssay Description:In vitro antiviral activity against hepatitis C virus (HCV) NS3 protease using scintillation proximity assayMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50216784(CHEMBL60795)
Show SMILES Brc1ccc(cc1)C(=O)OC1OCC=C2OC(=O)C=C12
Show InChI InChI=1S/C14H9BrO5/c15-9-3-1-8(2-4-9)13(17)20-14-10-7-12(16)19-11(10)5-6-18-14/h1-5,7,14H,6H2
Affinity DataIC50: 13nMAssay Description:In vitro antiviral activity against hepatitis C virus (HCV) NS3 protease using scintillation proximity assayMore data for this Ligand-Target Pair