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Found 17 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50002570
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023090(Boc-Phe-His-Sta-Leu-4-amido-1-benzylpiperidine | C...)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023094(Boc-Phe-His-Sta-Leu-erythro-1,2-diphenyl-2-hydroxy...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023094(Boc-Phe-His-Sta-Leu-erythro-1,2-diphenyl-2-hydroxy...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023096(Boc-Phe-His-Sta-Leu-(+)-alpha-phenylthylamide | CH...)
Affinity DataKi:  6nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023091(CHEMBL269752 | Iva-His-Pro-Phe-His-Sta-Leu-Phe-NH2)
Affinity DataKi:  17nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  20nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023086(Boc-Phe-His-Sta-Leu-1-hydroxy-1-phenyl-2-propylami...)
Affinity DataKi:  36nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023089(Boc-Phe-His-Sta-Leu-p-chlorobenzylamide | CHEMBL30...)
Affinity DataKi:  50nMAssay Description:Inhibition of human plasma renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)
Affinity DataKi:  55nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  68nMAssay Description:Inhibition of human plasma renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  68nMAssay Description:Inhibition of hog kidney renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023088(Boc-Phe-His-Sta-Leu-p-methoxybenzylamide | CHEMBL5...)
Affinity DataKi:  100nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023095(Boc-Phe-His-Sta-Leu-(+)-alpha-naphthylthylamide | ...)
Affinity DataKi:  230nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023095(Boc-Phe-His-Sta-Leu-(+)-alpha-naphthylthylamide | ...)
Affinity DataKi:  230nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023087(Boc-Phe-His-Sta-Leu-Phe-NH2 | Boc-Phe-His-Sta-Leu-...)
Affinity DataKi:  350nMAssay Description:Inhibition of purified human kidney renin, fluorometric assay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023087(Boc-Phe-His-Sta-Leu-Phe-NH2 | Boc-Phe-His-Sta-Leu-...)
Affinity DataKi:  350nMAssay Description:Inhibition of purified human kidney renin, fluorometric assay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023093(Boc-Phe-His-Sta-Leu-10,11-dihydro-5H-dibenzo[a,d]-...)
Affinity DataKi:  520nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed