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Found 34 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 369
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264121(3-(3-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264120(3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...)
Affinity DataKi:  0.140nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264112(3-(4-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataKi:  0.180nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264097(1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataKi:  0.190nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264096(3-(4-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataKi:  0.230nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264113(3-(3-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataKi:  0.310nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264104(3-(4-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataKi:  0.480nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264118(3-(4-(4-(4-(5-oxo-1,6-naphthyridin-6(5H)-yl)phenyl...)
Affinity DataKi:  0.5nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264109(3-(3-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataKi:  0.610nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264122(3-(4-(4-(4-(2-oxopyrazin-1(2H)-yl)phenyl)piperazin...)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264099(1-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...)
Affinity DataKi:  0.870nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264105(3-(3-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataKi:  0.890nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264091(3-(3-(4-(4-(2-oxopiperidin-1-yl)phenyl)piperazin-1...)
Affinity DataKi:  1.20nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264108(3-(4-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataKi:  1.20nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264098(3-(3-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataKi:  1.20nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264124(3-(4-(4-(4-(2-oxotetrahydropyrimidin-1(2H)-yl)phen...)
Affinity DataKi:  1.30nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264115(3-(5-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataKi:  1.5nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264119(3-(3-(4-(4-(5-oxo-1,6-naphthyridin-6(5H)-yl)phenyl...)
Affinity DataKi:  1.70nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264125(3-(3-(4-(4-(2-oxotetrahydropyrimidin-1(2H)-yl)phen...)
Affinity DataKi:  1.90nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264011(3-(4-(4-(4-(2-oxopiperidin-1-yl)phenyl)piperazin-1...)
Affinity DataKi:  1.90nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264093(3-(4-(4-(4-(3-oxomorpholino)phenyl)piperazin-1-yl)...)
Affinity DataKi:  2.10nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM263988(1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataKi:  2.5nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264123(3-(3-(4-(4-(2-oxopyrazin-1(2H)-yl)phenyl)piperazin...)
Affinity DataKi:  3nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264092(4-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataKi:  3.10nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264095(3-(3-(4-(4-(3-oxomorpholino)phenyl)piperazin-1-yl)...)
Affinity DataKi:  3.20nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264024(1-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...)
Affinity DataKi:  3.20nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264117(3-(3-(4-(4-(1-oxoisoquinolin-2(1H)-yl)phenyl)piper...)
Affinity DataKi:  3.60nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264101(3-(5-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataKi:  4.10nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264107(3-(5-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataKi:  4.70nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264094(4-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...)
Affinity DataKi:  6.40nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264111(3-(5-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataKi:  12nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264106(3-(2-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataKi:  33nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264100(3-(2-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataKi:  54nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264114(3-(2-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataKi:  68nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
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