Compile Data Set for Download or QSAR
Found 56 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50000013
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239170(CHEMBL4096571)
Show SMILES Fc1ccc2[nH]cc(Cc3c[nH]c4ccc(F)c(F)c34)c2c1F
Show InChI InChI=1S/C17H10F4N2/c18-10-1-3-12-14(16(10)20)8(6-22-12)5-9-7-23-13-4-2-11(19)17(21)15(9)13/h1-4,6-7,22-23H,5H2
Affinity DataEC50:  377nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239204(CHEMBL4087204)
Show SMILES Fc1cc2cc[nH]c2cc1F
Show InChI InChI=1S/C8H5F2N/c9-6-3-5-1-2-11-8(5)4-7(6)10/h1-4,11H
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239172(CHEMBL4088884)
Show SMILES Fc1cc(F)c2[nH]cc(Cc3c[nH]c4c(F)cc(F)cc34)c2c1
Show InChI InChI=1S/C17H10F4N2/c18-10-2-12-8(6-22-16(12)14(20)4-10)1-9-7-23-17-13(9)3-11(19)5-15(17)21/h2-7,22-23H,1H2
Affinity DataEC50:  41nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239173(CHEMBL4105236)
Show SMILES C(c1c[nH]c2ncccc12)c1c[nH]c2ncccc12
Show InChI InChI=1S/C15H12N4/c1-3-12-10(8-18-14(12)16-5-1)7-11-9-19-15-13(11)4-2-6-17-15/h1-6,8-9H,7H2,(H,16,18)(H,17,19)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239174(CHEMBL4097530)
Show SMILES CC(c1c[nH]c2cccc(F)c12)c1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C18H14F2N2/c1-10(11-8-21-15-6-2-4-13(19)17(11)15)12-9-22-16-7-3-5-14(20)18(12)16/h2-10,21-22H,1H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239175(CHEMBL4085470)
Show SMILES CCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C19H18N2/c1-2-13(16-11-20-18-9-5-3-7-14(16)18)17-12-21-19-10-6-4-8-15(17)19/h3-13,20-21H,2H2,1H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239169(CHEMBL4063898)
Show SMILES CCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H20N2/c1-2-7-14(17-12-21-19-10-5-3-8-15(17)19)18-13-22-20-11-6-4-9-16(18)20/h3-6,8-14,21-22H,2,7H2,1H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239176(CHEMBL4099626)
Show SMILES CC(C)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H20N2/c1-13(2)20(16-11-21-18-9-5-3-7-14(16)18)17-12-22-19-10-6-4-8-15(17)19/h3-13,20-22H,1-2H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239177(CHEMBL574338)
Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C24H20N2/c1-16-10-12-17(13-11-16)24(20-14-25-22-8-4-2-6-18(20)22)21-15-26-23-9-5-3-7-19(21)23/h2-15,24-26H,1H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239178(CHEMBL1939127)
Show SMILES Oc1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C23H18N2O/c26-16-11-9-15(10-12-16)23(19-13-24-21-7-3-1-5-17(19)21)20-14-25-22-8-4-2-6-18(20)22/h1-14,23-26H
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239179(CHEMBL2376559)
Show SMILES Clc1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C23H17ClN2/c24-16-11-9-15(10-12-16)23(19-13-25-21-7-3-1-5-17(19)21)20-14-26-22-8-4-2-6-18(20)22/h1-14,23,25-26H
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239180(CHEMBL4100585)
Show SMILES Fc1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C23H17FN2/c24-16-11-9-15(10-12-16)23(19-13-25-21-7-3-1-5-17(19)21)20-14-26-22-8-4-2-6-18(20)22/h1-14,23,25-26H
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239181(1,1,1-Tris(3-Indolyl)Methane | CHEMBL522998)
Show SMILES c1[nH]c2ccccc2c1C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C25H19N3/c1-4-10-22-16(7-1)19(13-26-22)25(20-14-27-23-11-5-2-8-17(20)23)21-15-28-24-12-6-3-9-18(21)24/h1-15,25-28H
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239182(CHEMBL1995195)
Show SMILES [O-][N+](=O)c1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C23H17N3O2/c27-26(28)16-11-9-15(10-12-16)23(19-13-24-21-7-3-1-5-17(19)21)20-14-25-22-8-4-2-6-18(20)22/h1-14,23-25H
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239183(CHEMBL4087824)
Show SMILES O=C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C17H12N2O/c20-17(13-9-18-15-7-3-1-5-11(13)15)14-10-19-16-8-4-2-6-12(14)16/h1-10,18-19H
Affinity DataEC50:  553nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239184(CHEMBL4095532)
Show SMILES COc1ccc2[nH]cc(Cc3c[nH]c4ccccc34)c2c1
Show InChI InChI=1S/C18H16N2O/c1-21-14-6-7-18-16(9-14)13(11-20-18)8-12-10-19-17-5-3-2-4-15(12)17/h2-7,9-11,19-20H,8H2,1H3
Affinity DataEC50:  1.89E+3nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239185(CHEMBL4075099)
Show SMILES Fc1ccc2[nH]cc(Cc3c[nH]c4ccccc34)c2c1
Show InChI InChI=1S/C17H13FN2/c18-13-5-6-17-15(8-13)12(10-20-17)7-11-9-19-16-4-2-1-3-14(11)16/h1-6,8-10,19-20H,7H2
Affinity DataEC50:  264nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Show SMILES CCCCCCCCCC(O)=O
Show InChI InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12)
Affinity DataEC50:  7.42E+3nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239186(1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...)
Show SMILES C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2
Affinity DataEC50:  252nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239188(CHEMBL4081701)
Show SMILES COc1ccc2c(Cc3c[nH]c4cc(OC)ccc34)c[nH]c2c1
Show InChI InChI=1S/C19H18N2O2/c1-22-14-3-5-16-12(10-20-18(16)8-14)7-13-11-21-19-9-15(23-2)4-6-17(13)19/h3-6,8-11,20-21H,7H2,1-2H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239189(CHEMBL4082668)
Show SMILES Fc1ccc2c(Cc3c[nH]c4cc(F)ccc34)c[nH]c2c1
Show InChI InChI=1S/C17H12F2N2/c18-12-1-3-14-10(8-20-16(14)6-12)5-11-9-21-17-7-13(19)2-4-15(11)17/h1-4,6-9,20-21H,5H2
Affinity DataEC50:  625nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239190(CHEMBL4100658)
Show SMILES Clc1ccc2c(Cc3c[nH]c4cc(Cl)ccc34)c[nH]c2c1
Show InChI InChI=1S/C17H12Cl2N2/c18-12-1-3-14-10(8-20-16(14)6-12)5-11-9-21-17-7-13(19)2-4-15(11)17/h1-4,6-9,20-21H,5H2
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239191(CHEMBL4062512)
Show SMILES Fc1cccc2c(Cc3c[nH]c4c(F)cccc34)c[nH]c12
Show InChI InChI=1S/C17H12F2N2/c18-14-5-1-3-12-10(8-20-16(12)14)7-11-9-21-17-13(11)4-2-6-15(17)19/h1-6,8-9,20-21H,7H2
Affinity DataEC50:  113nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239192(CHEMBL4077871)
Show SMILES Cc1cccc2[nH]cc(Cc3c[nH]c4cccc(C)c34)c12
Show InChI InChI=1S/C19H18N2/c1-12-5-3-7-16-18(12)14(10-20-16)9-15-11-21-17-8-4-6-13(2)19(15)17/h3-8,10-11,20-21H,9H2,1-2H3
Affinity DataEC50:  987nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239168(CHEMBL4101219)
Show SMILES Fc1cccc2[nH]cc(Cc3c[nH]c4cccc(F)c34)c12
Show InChI InChI=1S/C17H12F2N2/c18-12-3-1-5-14-16(12)10(8-20-14)7-11-9-21-15-6-2-4-13(19)17(11)15/h1-6,8-9,20-21H,7H2
Affinity DataEC50:  328nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239193(CHEMBL4066454)
Show SMILES Clc1cccc2[nH]cc(Cc3c[nH]c4cccc(Cl)c34)c12
Show InChI InChI=1S/C17H12Cl2N2/c18-12-3-1-5-14-16(12)10(8-20-14)7-11-9-21-15-6-2-4-13(19)17(11)15/h1-6,8-9,20-21H,7H2
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239194(CHEMBL4101728)
Show SMILES Fc1ccc2[nH]cc(Cc3c[nH]c4ccc(F)cc34)c2c1
Show InChI InChI=1S/C17H12F2N2/c18-12-1-3-16-14(6-12)10(8-20-16)5-11-9-21-17-4-2-13(19)7-15(11)17/h1-4,6-9,20-21H,5H2
Affinity DataEC50:  80nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239195(CHEMBL4096406)
Show SMILES Clc1ccc2[nH]cc(Cc3c[nH]c4ccc(Cl)cc34)c2c1
Show InChI InChI=1S/C17H12Cl2N2/c18-12-1-3-16-14(6-12)10(8-20-16)5-11-9-21-17-4-2-13(19)7-15(11)17/h1-4,6-9,20-21H,5H2
Affinity DataEC50:  4.96E+3nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239196(CHEMBL246504)
Show SMILES Brc1ccc2[nH]cc(Cc3c[nH]c4ccc(Br)cc34)c2c1
Show InChI InChI=1S/C17H12Br2N2/c18-12-1-3-16-14(6-12)10(8-20-16)5-11-9-21-17-4-2-13(19)7-15(11)17/h1-4,6-9,20-21H,5H2
Affinity DataEC50:  3.44E+3nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239197(CHEMBL578425)
Show SMILES [O-][N+](=O)c1ccc2[nH]cc(Cc3c[nH]c4ccc(cc34)[N+]([O-])=O)c2c1
Show InChI InChI=1S/C17H12N4O4/c22-20(23)12-1-3-16-14(6-12)10(8-18-16)5-11-9-19-17-4-2-13(21(24)25)7-15(11)17/h1-4,6-9,18-19H,5H2
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239198(CHEMBL4100764)
Show SMILES COC(=O)c1ccc2[nH]cc(Cc3c[nH]c4ccc(cc34)C(=O)OC)c2c1
Show InChI InChI=1S/C21H18N2O4/c1-26-20(24)12-3-5-18-16(8-12)14(10-22-18)7-15-11-23-19-6-4-13(9-17(15)19)21(25)27-2/h3-6,8-11,22-23H,7H2,1-2H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239199(CHEMBL4071153)
Show SMILES C(Oc1ccc2[nH]cc(Cc3c[nH]c4ccc(OCc5ccccc5)cc34)c2c1)c1ccccc1
Show InChI InChI=1S/C31H26N2O2/c1-3-7-22(8-4-1)20-34-26-11-13-30-28(16-26)24(18-32-30)15-25-19-33-31-14-12-27(17-29(25)31)35-21-23-9-5-2-6-10-23/h1-14,16-19,32-33H,15,20-21H2
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239205(CHEMBL4085348)
Show SMILES OC(=O)c1ccc2[nH]cc(Cc3c[nH]c4ccccc34)c2c1
Show InChI InChI=1S/C18H14N2O2/c21-18(22)11-5-6-17-15(8-11)13(10-20-17)7-12-9-19-16-4-2-1-3-14(12)16/h1-6,8-10,19-20H,7H2,(H,21,22)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239206(CHEMBL190134)
Show SMILES O=C1Nc2ccccc2\C1=C\c1c[nH]c2ccccc12
Show InChI InChI=1S/C17H12N2O/c20-17-14(13-6-2-4-8-16(13)19-17)9-11-10-18-15-7-3-1-5-12(11)15/h1-10,18H,(H,19,20)/b14-9-
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239207(CHEMBL4093108)
Show SMILES Fc1ccc2[nH]cc(C=C3C(=O)Nc4ccccc34)c2c1
Show InChI InChI=1S/C17H11FN2O/c18-11-5-6-15-13(8-11)10(9-19-15)7-14-12-3-1-2-4-16(12)20-17(14)21/h1-9,19H,(H,20,21)/b14-7-
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239208(CHEMBL4074055)
Show SMILES COc1ccc2[nH]cc(\C=C3/C(=O)Nc4ccccc34)c2c1
Show InChI InChI=1S/C18H14N2O2/c1-22-12-6-7-16-14(9-12)11(10-19-16)8-15-13-4-2-3-5-17(13)20-18(15)21/h2-10,19H,1H3,(H,20,21)/b15-8-
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239209(CHEMBL1914909)
Show SMILES Fc1ccc2NC(=O)\C(=C/c3c[nH]c4ccc(F)cc34)c2c1
Show InChI InChI=1S/C17H10F2N2O/c18-10-1-3-15-12(6-10)9(8-20-15)5-14-13-7-11(19)2-4-16(13)21-17(14)22/h1-8,20H,(H,21,22)/b14-5-
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239202(CHEMBL4087988)
Show SMILES COc1ccc2[nH]cc(C=C3C(=O)Nc4ccc(F)cc34)c2c1
Show InChI InChI=1S/C18H13FN2O2/c1-23-12-3-5-16-13(8-12)10(9-20-16)6-15-14-7-11(19)2-4-17(14)21-18(15)22/h2-9,20H,1H3,(H,21,22)/b15-6-
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239203(CHEMBL4059692)
Show SMILES O=C1Nc2ccccc2C1=Cc1ccc2[nH]ccc2c1
Show InChI InChI=1S/C17H12N2O/c20-17-14(13-3-1-2-4-16(13)19-17)10-11-5-6-15-12(9-11)7-8-18-15/h1-10,18H,(H,19,20)/b14-10-
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239210(CHEMBL4068351)
Show SMILES Fc1ccc2NC(=O)C(Cc3c[nH]c4ccc(F)cc34)c2c1
Show InChI InChI=1S/C17H12F2N2O/c18-10-1-3-15-12(6-10)9(8-20-15)5-14-13-7-11(19)2-4-16(13)21-17(14)22/h1-4,6-8,14,20H,5H2,(H,21,22)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239211(CHEMBL4103460)
Show SMILES COc1ccc2[nH]cc(CC3C(=O)Nc4ccc(F)cc34)c2c1
Show InChI InChI=1S/C18H15FN2O2/c1-23-12-3-5-16-13(8-12)10(9-20-16)6-15-14-7-11(19)2-4-17(14)21-18(15)22/h2-5,7-9,15,20H,6H2,1H3,(H,21,22)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239212(CHEMBL4079202)
Show SMILES O=C1Nc2ccccc2C1Cc1ccc2[nH]ccc2c1
Show InChI InChI=1S/C17H14N2O/c20-17-14(13-3-1-2-4-16(13)19-17)10-11-5-6-15-12(9-11)7-8-18-15/h1-9,14,18H,10H2,(H,19,20)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239216(CHEMBL4059770)
Show SMILES Cc1ccc2c(Cc3c[nH]c4cc(C)ccc34)c[nH]c2c1
Show InChI InChI=1S/C19H18N2/c1-12-3-5-16-14(10-20-18(16)7-12)9-15-11-21-19-8-13(2)4-6-17(15)19/h3-8,10-11,20-21H,9H2,1-2H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239217(CHEMBL4090496)
Show SMILES COc1cccc2c(Cc3c[nH]c4c(OC)cccc34)c[nH]c12
Show InChI InChI=1S/C19H18N2O2/c1-22-16-7-3-5-14-12(10-20-18(14)16)9-13-11-21-19-15(13)6-4-8-17(19)23-2/h3-8,10-11,20-21H,9H2,1-2H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239218(CHEMBL4104992)
Show SMILES Fc1cc2c(Cc3c[nH]c4cc(Cl)c(F)cc34)c[nH]c2cc1Cl
Show InChI InChI=1S/C17H10Cl2F2N2/c18-12-4-16-10(2-14(12)20)8(6-22-16)1-9-7-23-17-5-13(19)15(21)3-11(9)17/h2-7,22-23H,1H2
Affinity DataEC50:  1.08E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239219(CHEMBL246297)
Show SMILES Cn1cc(Cc2cn(C)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C19H18N2/c1-20-12-14(16-7-3-5-9-18(16)20)11-15-13-21(2)19-10-6-4-8-17(15)19/h3-10,12-13H,11H2,1-2H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239213(CHEMBL246298)
Show SMILES COc1ccc2[nH]cc(Cc3c[nH]c4ccc(OC)cc34)c2c1
Show InChI InChI=1S/C19H18N2O2/c1-22-14-3-5-18-16(8-14)12(10-20-18)7-13-11-21-19-6-4-15(23-2)9-17(13)19/h3-6,8-11,20-21H,7H2,1-2H3
Affinity DataEC50:  365nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239220(CHEMBL4082773)
Show SMILES O=Cc1ccc2[nH]cc(Cc3c[nH]c4ccc(C=O)cc34)c2c1
Show InChI InChI=1S/C19H14N2O2/c22-10-12-1-3-18-16(5-12)14(8-20-18)7-15-9-21-19-4-2-13(11-23)6-17(15)19/h1-6,8-11,20-21H,7H2
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239221(VIBRINDOLE A)
Show SMILES CC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C18H16N2/c1-12(15-10-19-17-8-4-2-6-13(15)17)16-11-20-18-9-5-3-7-14(16)18/h2-12,19-20H,1H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239222(CHEMBL4081624)
Show SMILES CCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H22N2/c1-2-3-8-15(18-13-22-20-11-6-4-9-16(18)20)19-14-23-21-12-7-5-10-17(19)21/h4-7,9-15,22-23H,2-3,8H2,1H3
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
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