Found 11 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50000170 TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:In vito concentration required to displace [3H]-DADLE (Kd = 12.2 nM and concentration is 2.1 nM) from low affinity delta-site in rat brain membranes.More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:In vito concentration required to displace [3H]cyclofoxy (Kd = 0.8 nM and concentration is 1.3 nM) from mu and kappa2 receptor in rat brain membranes...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:In vito concentration required to displace [3H]BRM (Kd = 1.0 nM and concentration is 1.8 nM) from opioid receptor kappa 2 in guinea brain membranes.More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
