Found 826 of ph data with Target = '5-hydroxytryptamine receptor 1A' Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.0640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.110nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.180nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.200nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.220nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.290nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -56.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.320nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.330nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.340nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.350nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.380nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.420nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.430nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.440nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.550nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.590nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional
receptor assays are available on the NIMH PDSP website at
http://pdsp.med.un...More data for this Ligand-Target Pair
Affinity DataKi: 0.610nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.780nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.850nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.870nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.890nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.970nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
