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Found 327 of ph data with Target = 'Histamine H3 receptor'
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27210((2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,...)
Affinity DataKi:  0.210nM ΔG°:  -55.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27208((2S,3S)-2-amino-N,3-dimethyl-N-[(1R,2S,5S,6S,9R,12...)
Affinity DataKi:  0.220nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  0.339nM ΔG°:  -54.1kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27209((2R,3R)-2-amino-N,3-dimethyl-N-[(1R,2S,5S,6S,9R,12...)
Affinity DataKi:  0.370nM ΔG°:  -53.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataKi:  0.407nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22548(2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4,6-trimeth...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/mole EC50:  2nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27212((2S)-2-acetamido-N-methyl-3-phenyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  1.15nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27211((2S)-2-acetamido-N,4-dimethyl-N-[(1R,2S,5S,6S,9R,1...)
Affinity DataKi:  1.62nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27201(4-{methyl[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trim...)
Affinity DataKi:  1.66nM ΔG°:  -50.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22538(4-Benzyl-1H-imidazole derivative, 19 | 4-{[3-(2-ph...)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22540(4-Benzyl-1H-imidazole derivative, 21 | 4-{[3-(pent...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27200(Conessine analogue, 12f | N-methyl-2-(thiophen-2-y...)
Affinity DataKi:  3.31nM ΔG°:  -48.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22529(2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-...)
Affinity DataKi:  4nM ΔG°:  -47.9kJ/mole EC50:  16nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22537(4-Benzyl-1H-imidazole derivative, 18 | 4-{[3-(3,3-...)
Affinity DataKi:  4nM ΔG°:  -47.9kJ/mole EC50:  8nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27193((1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethy...)
Affinity DataKi:  5.37nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128119(US8796297, 25)
Affinity DataKi:  5.75nM ΔG°:  -43.7kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM50361016(CHEMBL501882 | US8796297, 13)
Affinity DataKi:  7.41nM ΔG°:  -43.1kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27206(Conessine analogue, 12l | N-methyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  7.76nM ΔG°:  -46.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128117(US8796297, 23)
Affinity DataKi:  12.3nM ΔG°:  -42.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27197(Conessine analogue, 12c | N-methyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  12.3nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128103(US8796297, 6)
Affinity DataKi:  13.2nM ΔG°:  -41.8kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM26226((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)
Affinity DataKi:  13.5nM ΔG°:  -44.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50361016(CHEMBL501882 | US8796297, 13)
Affinity DataKi:  13.8nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27199(Conessine analogue, 12e | N-methyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  16.2nM ΔG°:  -44.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27207(4-cyano-N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6...)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27214(2,2,2-trichloroethyl N-methyl-N-[(1R,2S,5S,6S,9R,1...)
Affinity DataKi:  19.7nM ΔG°:  -44.0kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128120(US8796297, 2)
Affinity DataKi:  20nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27205(Conessine analogue, 12k | N-methyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  23.4nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM128119(US8796297, 25)
Affinity DataKi:  24nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128123(US8796297, 12)
Affinity DataKi:  24.5nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM128104(US8796297, 7)
Affinity DataKi:  28.2nM ΔG°:  -40.1kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27204(Conessine analogue, 12j | dimethyl({methyl[(1R,2S,...)
Affinity DataKi:  30.9nM ΔG°:  -42.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22536(1-[3-(1H-imidazol-4-ylmethyl)phenyl]-3,3-dimethylb...)
Affinity DataKi:  32nM ΔG°:  -42.8kJ/mole EC50:  79nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22533(4-Benzyl-1H-imidazole derivative, 14 | 4-[(3-pheny...)
Affinity DataKi:  33nM ΔG°:  -42.7kJ/mole EC50:  200nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM128116(US8796297, 22)
Affinity DataKi:  33.1nM ΔG°:  -39.7kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27194((1R,2S,5S,6S,9R,12S,13R,16S)-N,6,7,13-tetramethyl-...)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27198(4-cyano-N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6...)
Affinity DataKi:  39.8nM ΔG°:  -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22549(2-[3-(1H-imidazol-4-ylmethyl)phenyl]-3-oxa-1-azasp...)
Affinity DataKi:  40nM ΔG°:  -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22534(2-[3-(1H-imidazol-4-ylmethyl)phenyl]pyridine | 4-B...)
Affinity DataKi:  41nM ΔG°:  -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27203(1,3,3-trimethyl-1-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,...)
Affinity DataKi:  50.1nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM128120(US8796297, 2)
Affinity DataKi:  53.7nM ΔG°:  -38.6kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128115(US8796297, 21)
Affinity DataKi:  55nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22550(2-[3-(1H-imidazol-4-ylmethyl)phenyl]-1-oxa-3-azasp...)
Affinity DataKi:  56nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128114(US8796297, 20)
Affinity DataKi:  58.9nM ΔG°:  -38.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27202(Conessine analogue, 12h | methyl N-methyl-N-[(1R,2...)
Affinity DataKi:  60.3nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27196(Conessine analogue, 12b | N-methyl-N-[(1R,2S,5S,6S...)
Affinity DataKi:  60.3nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM128103(US8796297, 6)
Affinity DataKi:  61.7nM ΔG°:  -38.3kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27213(4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...)
Affinity DataKi:  63nM ΔG°:  -41.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM128117(US8796297, 23)
Affinity DataKi:  67.6nM ΔG°:  -38.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  72nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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