Compile Data Set for Download or QSAR
Found 105
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351251(CHEMBL1818523)
Affinity DataIC50:  30nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351251(CHEMBL1818523)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at Pseudomonas aeruginosa MW1 LasR assessed as inhibition of protein interaction with OdDHL by beta-galactosidase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351252(CHEMBL8755)
Affinity DataIC50:  40nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50350706(CHEMBL1811922)
Affinity DataIC50:  40nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351511(CHEMBL463321)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50241433((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Affinity DataIC50:  250nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli DH5alpha assessed as inhibition of protein interaction with OdDHL af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351509(CHEMBL8799)
Affinity DataIC50:  250nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351508(CHEMBL259352)
Affinity DataIC50:  340nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli DH5alpha assessed as inhibition of protein interaction with OdDHL af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50241433((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Affinity DataIC50:  340nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50241431((S)-2-(3-nitrophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Affinity DataIC50:  610nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli DH5alpha assessed as inhibition of protein interaction with OdDHL af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50241431((S)-2-(3-nitrophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Affinity DataIC50:  610nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465709(8-Azaguanine | CHEBI:63486)
Affinity DataIC50:  640nMAssay Description:Antagonist activity at LasR in Pseudomonas aeruginosa PAO1 harboring GFP-fused quorum sensing lasB measured every 15 mins for 14 hrs by GFP reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465704(CHEMBL4282406)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli DH5alpha assessed as inhibition of protein interaction with OdDHL af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351249(CHEMBL1818521)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO-JG21 LasR co-transfected with LVAgfp reporter assessed as inhibition of GFP production by fluorescence based...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50266163((S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Affinity DataIC50:  1.72E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465705(CHEMBL258912)
Affinity DataIC50:  1.72E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli DH5alpha assessed as inhibition of protein interaction with OdDHL af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351508(CHEMBL259352)
Affinity DataIC50:  1.75E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO-JP2 LasR co-transfected with LVAgfp reporter assessed as inhibition of GFP production by fluorescence based ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351251(CHEMBL1818523)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465706(CHEMBL4284314)
Affinity DataIC50:  2.64E+3nMAssay Description:Antagonist activity at LasR in Pseudomonas aeruginosa reporter strainMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50266165((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465698(CHEMBL3403857)
Affinity DataIC50:  3.27E+3nMAssay Description:Antagonist activity at LasR in Pseudomonas aeruginosa reporter strainMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465708(CHEMBL3403871)
Affinity DataIC50:  4.03E+3nMAssay Description:Antagonist activity at LasR in Pseudomonas aeruginosa reporter strainMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50266198((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Affinity DataIC50:  4.67E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in presence of 7.5 nM natural auto-inducer 3-oxo-C12-HSLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465697(CHEMBL4289544)
Affinity DataIC50:  5.20E+3nMAssay Description:Antagonist activity at LasR in Pseudomonas aeruginosa reporter strainMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50527001(CHEMBL1823942)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351511(CHEMBL463321)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50526996(CHEMBL4284234)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR transfected with lasB-GFP by luminescence methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50027796(2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa harboring GFP-fused quorum sensing lasB measured every 15 mins up to 12 hrs by GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50526982(CHEMBL4549418)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351250(CHEMBL1818522)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465701(CHEMBL4293495)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa MW1 LasR assessed as inhibition of protein interaction with OdDHL by beta-galactosidase reporter gene a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465700(CHEMBL4286873)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli DH5alpha assessed as inhibition of protein interaction with OdDHL af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50241433((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50350705(CHEMBL1814827)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PAO1 MW1 (pUM15) LasR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50300131(CHEMBL575294 | N-(4-bromophenylacetanoyl)-L-homose...)
Affinity DataIC50:  1.48E+4nMAssay Description:Antagonist activity at GFP-fused LasR in Pseudomonas aeruginosa PAO-JP2 co-expressing LVAgfp plasmid by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50300133(CHEMBL573744 | N-(indole-3-butanoyl)-L-homoserine ...)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50527020(CHEMBL4538227)
Affinity DataIC50:  1.50E+4nMAssay Description:Antagonist activity at LasR in Pseudomonas aeruginosa harboring plasI-LVAgfp assessed as inhibition of GFP production incubated for 6 hrs by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50240785((E)-1-Allyldisulfanyl-3-(prop-2-ene-1-sulfinyl)-pr...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa reporter strain harboring gfp-lasBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50300133(CHEMBL573744 | N-(indole-3-butanoyl)-L-homoserine ...)
Affinity DataIC50:  1.61E+4nMAssay Description:Antagonist activity at GFP-fused LasR in Pseudomonas aeruginosa PAO-JP2 co-expressing LVAgfp plasmid by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50300131(CHEMBL575294 | N-(4-bromophenylacetanoyl)-L-homose...)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50526976(CHEMBL1615001)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351506(CHEMBL1823934)
Affinity DataIC50:  3.00E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50300130(CHEMBL573745 | N-(2-cyclopentene-1-acetanoyl)-L-ho...)
Affinity DataIC50:  3.31E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM14324(5,6-dimethyl-1H-1,3-benzodiazol-2-amine | Fragment...)
Affinity DataIC50:  3.75E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LasR co-transfected with LVAgfp reporter assessed as inhibition of GFP production measured after 12 to 24 h...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50526999(CHEBI:63789 | CHEMBL458201)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50351505(CHEMBL1823935)
Affinity DataIC50:  4.52E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasR receptor assessed as inhibition of bioluminescence by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50465703(CHEMBL1823945)
Affinity DataIC50:  5.00E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa MW1 LasR assessed as inhibition of protein interaction with OdDHL by beta-galactosidase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50526981(N-CYCLOPENTYLDECANAMIDE)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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