Affinity DataEC50: 11nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Induction of DAT-mediated dopamine release in rat synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Agonist activity at rat DAT expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 47nMAssay Description:Induction of DAT-mediated dopamine release in rat synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 54nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 58nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 64nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 75nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 78nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 79nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 82nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 98nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 106nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 106nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 113nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 133nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 142nMAssay Description:Antagonist activity against human progesterone receptor (hPR) using cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 164nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 225nMAssay Description:Induction of DAT-mediated dopamine release in rat synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 232nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 276nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 278nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 321nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 353nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 411nMAssay Description:Induction of DAT-mediated dopamine release in rat synaptosomesMore data for this Ligand-Target Pair
Affinity DataEC50: 464nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 465nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 476nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 478nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 496nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 592nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 597nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 654nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 656nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 716nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 733nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 869nMAssay Description:Agonist activity at rat DAT expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.12E+3nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rti International
Curated by ChEMBL
Rti International
Curated by ChEMBL
Affinity DataEC50: 1.33E+3nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair