Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ec50 data for polymerid = 49000035,49000036,49000037
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(CHEMBL339980 | N-[3-(2-Dimethylamino-ethyl)-2-meth...)
Affinity DataEC50:  6nMAssay Description:In vitro effective concentration for inhibition of skolin-stimulated adenylate cyclase in cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  7.90nMAssay Description:In vitro effective concentration for inhibition of skolin-stimulated adenylate cyclase in cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130447(CHEMBL104753 | Thiophene-3-carboxylic acid [3-(1-m...)
Affinity DataEC50:  9.40nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130437(CHEMBL105958 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataEC50:  11nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130420(CHEMBL105091 | Furan-2-carboxylic acid [3-(1-methy...)
Affinity DataEC50:  11nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130439(CHEMBL102250 | Furan-3-carboxylic acid [3-(1-methy...)
Affinity DataEC50:  11nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130465(CHEMBL105955 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataEC50:  13nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130467(CHEMBL321080 | Thiophene-2-carboxylic acid [3-(1-m...)
Affinity DataEC50:  15nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130433(CHEMBL420475 | Cyclobutanecarboxylic acid [3-(1-me...)
Affinity DataEC50:  21nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130442(CHEMBL105722 | Pyridine-2-carboxylic acid [3-(1-me...)
Affinity DataEC50:  25nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataEC50:  32nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130440(CHEMBL104720 | Cyclopropanecarboxylic acid [3-(1-m...)
Affinity DataEC50:  34nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataEC50:  35nMAssay Description:In vitro effective concentration for inhibition of skolin-stimulated adenylate cyclase in cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataEC50:  36nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-HT1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50156408(2,4,6-Trifluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3...)
Affinity DataEC50:  50nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding to cloned human 5-hydroxytryptamine 1F receptor expressed in Mouse LM(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119542(CHEMBL3617550)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human 5HT1F receptor expressed in LM(tk-) cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50156403(2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-2...)
Affinity DataEC50:  63nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding to cloned human 5-hydroxytryptamine 1F receptor expressed in Mouse LM(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137541(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-furo[3,2-b...)
Affinity DataEC50:  66nMAssay Description:Concentration required for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-1) cells expressing the human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137540(2-Chloro-6-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...)
Affinity DataEC50:  69nMAssay Description:Concentration required for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-1) cells expressing the human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119543(CHEMBL3617549)
Affinity DataEC50:  87nMAssay Description:Agonist activity at human 5HT1F receptor expressed in LM(tk-) cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137539(2,4,6-Trifluoro-N-[3-(1-methyl-piperidin-4-yl)-fur...)
Affinity DataEC50:  92nMAssay Description:Concentration required for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-1) cells expressing the human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119532(CHEMBL3617557)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human 5HT1F receptor expressed in LM(tk-) cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50156409(2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-b...)
Affinity DataEC50:  140nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding to cloned human 5-hydroxytryptamine 1F receptor expressed in Mouse LM(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137538(2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...)
Affinity DataEC50:  277nMAssay Description:In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50156406(2,4-Difluoro-N-[3-(1-methyl-piperidin-4-yl)-benzo[...)
Affinity DataEC50:  470nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding to cloned human 5-hydroxytryptamine 1F receptor expressed in Mouse LM(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed