Compile Data Set for Download or QSAR
maximum 50k data
Found 86 of ec50 data for polymerid = 49000646
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414494(CHEMBL564300)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414492(CHEMBL564914)
Affinity DataEC50:  14nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414513(CHEMBL394468)
Affinity DataEC50:  42nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384637(CHEMBL2036951)
Affinity DataEC50:  59nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384640(CHEMBL2036954)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384612(CHEMBL2036958)
Affinity DataEC50:  96nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384641(CHEMBL2036955)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414491(CHEMBL559204)
Affinity DataEC50:  141nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208135((+)-5-methyl-5-(5-methyl-thiophen-3-yl)-4-oxo-4,5-...)
Affinity DataEC50:  180nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384616(CHEMBL2036813)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475630(CHEMBL382096)
Affinity DataEC50:  200nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475626(CHEMBL372727)
Affinity DataEC50:  257nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475631(CHEMBL202351)
Affinity DataEC50:  257nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414495(CHEMBL562675)
Affinity DataEC50:  257nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208140(5-methyl-5-(5-methyl-thiophen-2-yl)-4-oxo-4,5-dihy...)
Affinity DataEC50:  270nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475629(CHEMBL201048)
Affinity DataEC50:  288nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337038(5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyra...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475639(CHEMBL201409)
Affinity DataEC50:  302nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...)
Affinity DataEC50:  316nMAssay Description:Agonist activity at HCA3 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475645(CHEMBL202157)
Affinity DataEC50:  316nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475637(CHEMBL202206)
Affinity DataEC50:  331nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241028(1-Isopropyl-1H-benzotriazole-5-carboxylic acid | 1...)
Affinity DataEC50:  398nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475635(CHEMBL202586)
Affinity DataEC50:  692nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220833(5-(5-propyl-1H-pyrazol-3-yl)-1H-tetrazole | CHEMBL...)
Affinity DataEC50:  724nMAssay Description:Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220833(5-(5-propyl-1H-pyrazol-3-yl)-1H-tetrazole | CHEMBL...)
Affinity DataEC50:  724nMAssay Description:Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414499(CHEMBL561920)
Affinity DataEC50:  851nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475633(CHEMBL440217)
Affinity DataEC50:  891nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475638(CHEMBL201724)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  1.12E+3nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50384634(CHEMBL2036948)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208137((+)-5-(5-bromo-thiophen-3-yl)-5-methyl-4-oxo-4,5-d...)
Affinity DataEC50:  1.47E+3nMAssay Description:Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208137((+)-5-(5-bromo-thiophen-3-yl)-5-methyl-4-oxo-4,5-d...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208122((+)-5-(5-chloro-thiophen-3-yl)-5-methyl-4-oxo-4,5-...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208122((+)-5-(5-chloro-thiophen-3-yl)-5-methyl-4-oxo-4,5-...)
Affinity DataEC50:  1.72E+3nMAssay Description:Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208134(5-methyl-5-(4-methyl-thiophen-2-yl)-4-oxo-4,5-dihy...)
Affinity DataEC50:  1.80E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475642(CHEMBL201513)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475640(CHEMBL380939)
Affinity DataEC50:  2.34E+3nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475643(CHEMBL370386)
Affinity DataEC50:  3.02E+3nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475641(CHEMBL440041)
Affinity DataEC50:  3.09E+3nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220853(5-(5-cyclopropyl-1H-pyrazol-3-yl)-1H-tetrazole | C...)
Affinity DataEC50:  3.23E+3nMAssay Description:Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220853(5-(5-cyclopropyl-1H-pyrazol-3-yl)-1H-tetrazole | C...)
Affinity DataEC50:  3.23E+3nMAssay Description:Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475632(CHEMBL382863)
Affinity DataEC50:  3.39E+3nMAssay Description:Agonistic activity at GPR109b by cAMP whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208116(5-(5-chloro-thiophen-2-yl)-5-methyl-4-oxo-4,5-dihy...)
Affinity DataEC50:  3.70E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414502(CHEMBL561720)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208110(5-methyl-5-(4-bromo-thiophen-2-yl)-4-oxo-4,5-dihyd...)
Affinity DataEC50:  4.10E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at N-terminal HA-tagged GPR109b receptor transfected in forskolin-stimulated cells assessed as cAMP accumulation by flashplate assayMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208139(5-methyl-4-oxo-5-thiophen-3-yl-4,5-dihydro-furan-2...)
Affinity DataEC50:  4.20E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...)
Affinity DataEC50:  4.20E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50414506(CHEMBL553415)
Affinity DataEC50:  4.47E+3nMAssay Description:Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208125(5-ethyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxy...)
Affinity DataEC50:  4.80E+3nMAssay Description:Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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