Found 182 of ec50 data for polymerid = 50000606,50001237,50001880,50002487,50002529 TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 8nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 20nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 20nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 23nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 30nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 34nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 40nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 49nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 50nMAssay Description:Agonist activity at Kv7.2 (unknown origin) assessed as shifting of voltage dependent activation to more negative potentials by SyncroPatch assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 57nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 65nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 71nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 80nMAssay Description:Activation of human Kv7.2 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 87nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 88nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 98nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 120nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 130nMAssay Description:Activation of KCNQ2 (unknown origin) expressed in CHO cells at 10 uM after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 140nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 147nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: <150nMAssay Description:Activity at Kv 7.2 channel expressed in cloned CHO cells by [86Rb] efflux assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 170nMAssay Description:Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 220nMAssay Description:Activation of KCNQ2 (unknown origin) expressed in CHO cells at 10 uM after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 250nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 260nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 272nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 290nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 300nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 320nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 330nMAssay Description:Activation of KCNQ2 (unknown origin) expressed in CHO cells at 10 uM after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 5(Homo sapiens (Human))
University Federico Ii Of Naples
Curated by ChEMBL
University Federico Ii Of Naples
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Activation of human Kv7.5 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 350nMAssay Description:Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 350nMAssay Description:Activation of KCNQ2 (unknown origin) expressed in CHO cells at 10 uM after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 350nMAssay Description:Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 409nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 420nMAssay Description:Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 490nMAssay Description:Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 5(Homo sapiens (Human))
University Federico Ii Of Naples
Curated by ChEMBL
University Federico Ii Of Naples
Curated by ChEMBL
Affinity DataEC50: 540nMAssay Description:Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 625nMAssay Description:Activation of human Kv7.4 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 630nMAssay Description:Activation of human Kv7.2 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 660nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Shanghai Zhimeng Biopharma
US Patent
Shanghai Zhimeng Biopharma
US Patent
Affinity DataEC50: 690nMAssay Description:Effective concentration against Potassium voltage gated channel, KQT-like subfamily, member 2 expressed in SH-SY5Y human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assayMore data for this Ligand-Target Pair
