Compile Data Set for Download or QSAR
maximum 50k data
Found 353 of ec50 data for polymerid = 50000871,5269
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM23927(2,3,7,8-Tetrachlorodibenzo-p-dioxin | 2,3,7,8-tetr...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.0580nMAssay Description:Activation of AhR in mouse NIH3T3 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541261(CHEMBL4646273)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603538(CHEMBL5190861)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603539(CHEMBL5021347)
Affinity DataEC50:  0.340nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603551(CHEMBL5194336)
Affinity DataEC50:  0.440nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408372(CHEMBL137408)
Affinity DataEC50:  0.447nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.700nMAssay Description:Activation of AhR in human HaCaT cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603554(CHEMBL5181725)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408356(CHEMBL136453)
Affinity DataEC50:  1.17nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408320(CHEMBL136430)
Affinity DataEC50:  1.48nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408296(CHEMBL341968)
Affinity DataEC50:  1.5nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605060(CHEMBL5198290)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50563366(CHEMBL4764225)
Affinity DataEC50:  2nMAssay Description:Agonist activity at AHR in human HepG2 cells incubated for 4.5 hrs by Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50563365(CHEMBL4750416)
Affinity DataEC50:  2nMAssay Description:Agonist activity at AHR in human HepG2 cells incubated for 4.5 hrs by Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408359(CHEMBL137055)
Affinity DataEC50:  2nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541262(6-Formylindolo[3,2-B]Carbazole | CHEMBL472031)
Affinity DataEC50:  2nMAssay Description:Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  3.20nMAssay Description:Activation of AhR in human HepG2 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50137506((B(a)P) | 3,4-BP | 3,4-Benzopyrene | 3,4-Benzpyren...)
Affinity DataEC50:  5nMAssay Description:Concentration of the compound to bind to human AhR-modied electrodeMore data for this Ligand-Target Pair
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408303(CHEMBL137665)
Affinity DataEC50:  6.61nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50028963(3-Phenyl-1H-naphtho[2,1-b]pyran-1-one | 3-Phenyl-b...)
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603555(CHEMBL5199691)
Affinity DataEC50:  9.60nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR in mouse Hepa2Dluc cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM23927(2,3,7,8-Tetrachlorodibenzo-p-dioxin | 2,3,7,8-tetr...)
Affinity DataEC50:  10nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408353(CHEMBL138223)
Affinity DataEC50:  11.5nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408369(CHEMBL335558)
Affinity DataEC50:  15.1nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408334(CHEMBL135555)
Affinity DataEC50:  15.5nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408300(CHEMBL422101)
Affinity DataEC50:  17.0nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM75530(MLS001200027 | N-(4-chlorophenyl)-4-methyl-2-(meth...)
Affinity DataEC50:  22.2nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603563(CHEMBL5198934)
Affinity DataEC50:  23nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408293(CHEMBL336463)
Affinity DataEC50:  25.1nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603566(Benvitimod | GSK-2894512 | GSK2894512 | TAPINAROF ...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605062(CHEMBL5185943)
Affinity DataEC50:  32nMAssay Description:Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408308(CHEMBL136710)
Affinity DataEC50:  41.0nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408302(CHEMBL343049)
Affinity DataEC50:  46.8nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50506038(CHEMBL4580482)
Affinity DataEC50:  49nMAssay Description:Binding affinity to AhR (unknown origin) relative to TCDDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50049061(CHEMBL3319501 | US10730833, Compound 11d | US99696...)
Affinity DataEC50:  55nMAssay Description:Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50049061(CHEMBL3319501 | US10730833, Compound 11d | US99696...)
Affinity DataEC50:  55nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50049061(CHEMBL3319501 | US10730833, Compound 11d | US99696...)
Affinity DataEC50:  55nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603544(CHEMBL5195426)
Affinity DataEC50:  62nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408340(CHEMBL136782)
Affinity DataEC50:  67.8nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM75514(2-N,5-N-bis(2-methoxyphenyl)pyridine-2,5-dicarboxa...)
Affinity DataEC50:  68.6nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408314(CHEMBL136335)
Affinity DataEC50:  71.0nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  71nMAssay Description:Activation of AhR in mouse Hepa1c1c7 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408381(CHEMBL137304)
Affinity DataEC50:  74.1nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603542(CHEMBL5183442)
Affinity DataEC50:  77nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50408363(CHEMBL137220)
Affinity DataEC50:  79.4nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603546(CHEMBL5207451)
Affinity DataEC50:  83nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50049057(CHEMBL3319505 | US10730833, Compound 10d | US99696...)
Affinity DataEC50:  86nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails US Patent
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