Compile Data Set for Download or QSAR
maximum 50k data
Found 29 of ec50 data for polymerid = 5137
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50363325(CHEMBL1945843)
Affinity DataEC50:  1.10nMAssay Description:Antagonist activity at human recombinant 5HT3 receptor assessed as inhibition of RAMH-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334438((R)-7-oxo-N-(quinuclidin-3-yl)-4,7-dihydrothieno[3...)
Affinity DataEC50:  5.40nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334439((R)-2-methyl-7-(quinuclidin-3-yl)-7,8-dihydropyraz...)
Affinity DataEC50:  6.90nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 10 uM 5-chloroindole-induced increase in intracell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334438((R)-7-oxo-N-(quinuclidin-3-yl)-4,7-dihydrothieno[3...)
Affinity DataEC50:  9.20nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 10 uM 5-chloroindole-induced increase in intracell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334439((R)-2-methyl-7-(quinuclidin-3-yl)-7,8-dihydropyraz...)
Affinity DataEC50:  12.6nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334440((R)-7-(quinuclidin-3-yl)-7,8-dihydropyrazolo[3,4,5...)
Affinity DataEC50:  14.5nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM36022((+/-)-octopamine | Octopamine,(+/-))
Affinity DataEC50:  24nMAssay Description:Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  141nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 10 uM 5-chloroindole-induced increase in intracell...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  178nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014556(CHEMBL3261486 | US9045501, 25)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014554(CHEMBL3261485)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014552(CHEMBL3261483 | US9045501, 8)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014551(CHEMBL3261482)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014548(CHEMBL3261479 | US9045501, 2)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50103074(1-Allyl-2-piperazin-1-yl-1H-benzoimidazole | CHEMB...)
Affinity DataEC50:  240nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50443668(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human wild type 5-HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  457nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in xenopus oocytes by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50301927(CHEMBL1748 | Norcisapride)
Affinity DataEC50:  2.30E+3nMAssay Description:Antagonist activity at human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human 5-HT43A receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50516235(CHEMBL4563408)
Affinity DataEC50: >1.00E+4nMAssay Description:Displacement of [3H]BRL43694 from recombinant human 5HT3 receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50229715(CHEMBL4070615)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at 5-HT3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50464234(CHEMBL4284872)
Affinity DataEC50: >2.50E+4nMAssay Description:Potentiation of human 5-HT3A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50238419(CHEMBL4060134)
Affinity DataEC50:  2.51E+4nMAssay Description:Inhibition of human serotonin receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM29135(CHEMBL11608 | cid_5610 | p-Tyramine | tyramine)
Affinity DataEC50:  2.60E+4nMAssay Description:Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataEC50: <5.01E+4nMAssay Description:Agonist activity at human 5-HT3 receptor by FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataEC50: <5.01E+4nMAssay Description:Agonist activity at human 5-HT3 receptor by FLIPR(Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed