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Found 9 of ec50 data for polymerid = 7135
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50200622(CHEMBL3917975)
Affinity DataEC50:  25nMAssay Description:Inhibition of human recombinant ATX/LPC 18:1-mediated mouse 4T1 cell migration after overnight incubation by Transwell assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50605406(CHEMBL5190935)
Affinity DataEC50:  60nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as ERK phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50605406(CHEMBL5190935)
Affinity DataEC50:  60nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as AKT phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50605405(CHEMBL5196449)
Affinity DataEC50:  100nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as AKT phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50605405(CHEMBL5196449)
Affinity DataEC50:  100nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as ERK phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50605406(CHEMBL5190935)
Affinity DataEC50:  186nMAssay Description:Inhibition of LPA-mediated ATX activation in human MDA-MB-231 cells assessed as reduction in cell migration incubated for 4 hrs in using18:1 LPC as s...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50439703(CHEMBL2418930)
Affinity DataEC50:  2.79E+3nMAssay Description:Activation of C-terminal FLAG-tagged human recombinant autotaxin using paranitrophenyl thymidine monophosphate as substrate measured every 2 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50439706(CHEMBL2418933)
Affinity DataEC50:  4.31E+3nMAssay Description:Activation of C-terminal FLAG-tagged human recombinant autotaxin using paranitrophenyl thymidine monophosphate as substrate measured every 2 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus

Curated by ChEMBL
LigandPNGBDBM50439704(CHEMBL2418934)
Affinity DataEC50:  4.44E+3nMAssay Description:Activation of C-terminal FLAG-tagged human recombinant autotaxin using paranitrophenyl thymidine monophosphate as substrate measured every 2 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed