Compile Data Set for Download or QSAR
maximum 50k data
Found 1008 of ic50 data for polymerid = 2142
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328390(3-(difluoromethyl)-6-fluoro-1-((4-methoxy-3-(4-met...)
Affinity DataIC50:  0.0660nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328384(3-(difluoromethyl)-5-fluoro-1-((4-methoxy-3-(4-met...)
Affinity DataIC50:  0.0740nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328391(6-chloro-3-(difluoromethyl)-1-((4-methoxy-3-(piper...)
Affinity DataIC50:  0.0850nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328394(3-(difluoromethyl)-6-bromo-1-((4-methoxy-3-(4-meth...)
Affinity DataIC50:  0.0900nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328397(6-chloro-3-(difluoromethyl)-1-((3-(4-isopropylpipe...)
Affinity DataIC50:  0.0900nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328396(6-chloro-1-((3-(4-cyclopropylpiperazin-1-yl)-4-met...)
Affinity DataIC50:  0.0920nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328392(3-(difluoromethyl)-6-chloro-1-((4-methoxy-3-(4-met...)
Affinity DataIC50:  0.100nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328395(6-chloro-3-(difluoromethyl)-1-((3-(4-ethylpiperazi...)
Affinity DataIC50:  0.130nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328400(3-(difluoromethyl)-1-((4-methoxy-3-(4-methylpipera...)
Affinity DataIC50:  0.140nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328380(6-chloro-1-((4-methoxy-3-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  0.140nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50156203(CHEMBL3781299)
Affinity DataIC50:  0.170nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328381(6-bromo-1-((4-methoxy-3-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50:  0.170nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328388(3-(difluoromethyl)-5-bromo-1-((4-methoxy-3-(4-meth...)
Affinity DataIC50:  0.200nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328379(6-chloro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Affinity DataIC50:  0.210nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328386(5-chloro-3-(difluoromethyl)-1-((4-methoxy-3-(4-met...)
Affinity DataIC50:  0.220nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM111790(US8618114, 1.2.22(5).HCl)
Affinity DataIC50:  0.227nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328401(3-(difluoromethyl)-1-((3-(4-ethylpiperazin-1-yl)-4...)
Affinity DataIC50:  0.25nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328389(3-(difluoromethyl)-6-fluoro-1-((4-methoxy-3-(piper...)
Affinity DataIC50:  0.260nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50156201(CHEMBL3781323)
Affinity DataIC50:  0.280nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM111771(US8618114, 1.2.11(1))
Affinity DataIC50:  0.293nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50156209(CHEMBL3780579)
Affinity DataIC50:  0.310nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328393(3-(difluoromethyl)-6-bromo-1-((4-methoxy-3-(pipera...)
Affinity DataIC50:  0.330nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50417932(CHEMBL1668587 | US8618114, 1.2.4(1))
Affinity DataIC50:  0.340nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50158027(4-[5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-i...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328399(3-(difluoromethyl)-1-((4-methoxy-3-(piperazin-1-yl...)
Affinity DataIC50:  0.400nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328402(1-((3-(4-cyclopropylpiperazin-1-yl)-4-methoxypheny...)
Affinity DataIC50:  0.400nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328408(5-fluoro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Affinity DataIC50:  0.430nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
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In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328366(4-fluoro-1-((4-methoxy-3-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  0.430nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328412(6-chloro-3-ethyl-1-((4-methoxy-3-(piperazin-1-yl)p...)
Affinity DataIC50:  0.450nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50156226(CHEMBL3781452)
Affinity DataIC50:  0.460nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328383(3-(difluoromethyl)-5-fluoro-1-((4-methoxy-3-(piper...)
Affinity DataIC50:  0.460nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328398(6-chloro-1-((3-(4-cyclobutylpiperazin-1-yl)-4-meth...)
Affinity DataIC50:  0.5nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50156199(CHEMBL3779904)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328404(5,6-dichloro-3-(difluoromethyl)-1-((4-methoxy-3-(p...)
Affinity DataIC50:  0.540nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328387(5-bromo-3-(difluoromethyl)-1-((4-methoxy-3-(pipera...)
Affinity DataIC50:  0.550nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM111787(US8618114, 1.2.22(2).HCl)
Affinity DataIC50:  0.560nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328382(7-fluoro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Affinity DataIC50:  0.570nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328407(6-bromo-3-(difluoromethyl)-1-((4-methoxy-3-(pipera...)
Affinity DataIC50:  0.580nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328362(1-((4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)sul...)
Affinity DataIC50:  0.590nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50169599(1-Benzenesulfonyl-3-((R)-1-methyl-pyrrolidin-2-ylm...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328413(6-bromo-3-ethyl-1-((4-methoxy-3-(piperazin-1-yl)ph...)
Affinity DataIC50:  0.600nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328411(3-ethyl-6-fluoro-1-((4-methoxy-3-(piperazin-1-yl)p...)
Affinity DataIC50:  0.630nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328385(5-chloro-3-(difluoromethyl)-1-((4-methoxy-3-(piper...)
Affinity DataIC50:  0.640nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM111788(US8618114, 1.2.22(3).HCl)
Affinity DataIC50:  0.645nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328409(5-chloro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Affinity DataIC50:  0.670nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM328378(6-fluoro-1-((4-methoxy-3-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  0.670nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM111785(US8618114, 1.2.22(1).HCl)
Affinity DataIC50:  0.670nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50156200(CHEMBL3780274)
Affinity DataIC50:  0.690nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50158048(1-(2-Chloro-benzenesulfonyl)-3-(1-methyl-1,2,3,6-t...)
Affinity DataIC50:  0.700nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM50139789(CHEMBL353389 | {3-[2-(3-Bromo-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of the compound against human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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